Semisynthesis and pharmacological investigation of lipo-alkaloids prepared from aconitine by transesterification with eicosanoic acid analogues

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
B Borcsa ◽  
U Widowitz ◽  
D Csupor ◽  
P Forgo ◽  
R Bauer ◽  
...  
Keyword(s):  
Pharmacological Investigation ◽  
Eicosanoic Acid

Phytochemical and pharmacological investigation of Sideritis montana L.

2017 ◽  
Author(s):  
B Tóth ◽  
N Kúsz ◽  
N Bózsity ◽  
I Zupkó ◽  
V Csizmadia ◽  
...  
Keyword(s):  
Pharmacological Investigation

Novel GABAA Agonist Entities: Pharmacological Investigation and Molecular Modeling Study of Thiazolo- and Thiadiazolo-[3,2-a][1,3] diazepine Analogs

2020 ◽  
Vol 21 ◽  
Author(s):  
Hussein I. El-Subbagh
Keyword(s):  
Molecular Modeling ◽  
Drug Development ◽  
Biological Evaluation ◽  
Neuromuscular Blocking ◽  
Present Review ◽  
Pharmacological Investigation ◽  
Important Class ◽  
Pharmacological Activities ◽  
Short Acting ◽  
New Drug Development

Abstract:: Thiazolo- and thiadiazolo-[3,2-a][1,3]diazepines and their patented derivatives, tested with diverse CNS pharmacological activities, constitute an important class of compounds for new drug development. Therefore, research efforts were continued to design, synthesize, and evaluate compounds for their ultra-short, short-acting hypnotic, anticonvulsant, and neuromuscular blocking activities. The present review provides a summary of the work accomplished by these heterocycles and their biological evaluation.

Preparation and pharmacological investigation of suppositories containing mefenamic acid

1976 ◽  
Vol 10 (10) ◽  
pp. 1318-1320
Author(s):  
V. A. Golovkin ◽  
E. P. Lukash ◽  
V. R. Stets ◽  
B. V. Kurmaz
Keyword(s):  
Mefenamic Acid ◽  
Pharmacological Investigation

ChemInform Abstract: Synthesis and Pharmacological Investigation of the Enantiomers of Muscarone and Allomuscarone.

ChemInform ◽  
2010 ◽  
Vol 24 (1) ◽  
pp. no-no
Author(s):  
M. DE AMICI ◽  
C. DALLANOCE ◽  
C. DE MICHELI ◽  
E. GRANA ◽  
A. BARBIERI ◽  
...  
Keyword(s):  
Pharmacological Investigation

scholarly journals Biochemical and pharmacological investigation of novel nociceptin/OFQ analogues and N/OFQ-RYYRIK hybrid peptides

Peptides ◽  
2019 ◽  
Vol 112 ◽  
pp. 106-113 ◽  
Author(s):  
Anna I. Erdei ◽  
Adina Borbély ◽  
Anna Magyar ◽  
Edina Szűcs ◽  
Ferenc Ötvös ◽  
...  
Keyword(s):  
Pharmacological Investigation ◽  
Hybrid Peptides

THE APPLICATION OF THE ARNDT–EISTERT REACTION TO THE SYNTHESIS OF FATTY ACIDS OF HIGH MOLECULAR WEIGHT

1950 ◽  
Vol 28b (9) ◽  
pp. 556-560 ◽  
Author(s):  
F. A. Vandenheuvel ◽  
P. Yates
Keyword(s):  
Fatty Acids ◽  
Molecular Weight ◽  
Carboxylic Acid ◽  
Stearic Acid ◽  
High Molecular Weight ◽  
Efficient Method ◽  
Convenient Method ◽  
Ultraviolet Absorption ◽  
Aliphatic Carboxylic Acid ◽  
Eicosanoic Acid

The Arndt–Eistert reaction offers a convenient method for the synthesis of the higher members of the aliphatic carboxylic acid series. Nonadecanoic acid, eicosanoic acid, and heneicosanoic acid have been prepared successively from stearic acid in good yields. An efficient method of purification of the synthetic products is described. The ultraviolet absorption maxima for some diazoketones derived from the higher members of the aliphatic carboxylic acid series are recorded.

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