Medicinal Plants from Jordan in the Treatment of Diabetes: Traditional Uses vs.In VitroandIn VivoEvaluations – Part 2

AbstractMedicinal plants that are used today have been known by people of ancient cultures around the world and have largely been considered due to their medicinal properties.

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Glycogen Phosphorylase-a is a Common Target for Anti-Diabetic Effect of Iridoid and Secoiridoid Glycosides

Journal of Pharmacy & Pharmaceutical Sciences ◽

10.18433/j3fs4f ◽

2013 ◽

Vol 16 (4) ◽

pp. 530 ◽

Cited By ~ 15

Author(s):

Hitesh B Vaidya ◽

Abeer A Ahmed ◽

Ramesh K Goyal ◽

Sukhinder K Cheema

Keyword(s):

Diabetes Mellitus ◽

Medicinal Plants ◽

Glycogen Phosphorylase ◽

Docking Studies ◽

Chemical Components ◽

Active Components ◽

Active Chemical ◽

Treatment Of Diabetes ◽

Secoiridoid Glycosides ◽

Common Target

Purpose. Diabetes mellitus is characterized by hyperglycemia resulting from defects in insulin secretion, action or both. The use of medicinal plants for the treatment of diabetes mellitus dates back from the Ebers papyrus of about 1550 B.C. One of the major problems with herbal drugs is that the active ingredients are not well defined. It is important to know the active components and their molecular interactions which will help to analyze their therapeutic efficacy and also to standardize the product. There are a number of medicinal plants known for their anti-diabetic effect that possess similarities in their active chemical components, e.g. iridoid and secoiridoid glycosides. Methods. In this study, we have compared the structure of various iridoid and secoiridoid glycosides to design a novel pharmacophore. We further developed a structure-activity relationship for the inhibition of glycogen phosphorylase-a. Conclusion. By using docking studies, we are proposing, for the first time, that inhibition of glycogen phosphorylase-a activity is a common target for iridoids and secoiridoids to elicit anti-diabetic effects. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

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The Phytochemistry of Cherokee Aromatic Medicinal Plants

Medicines ◽

10.3390/medicines5040121 ◽

2018 ◽

Vol 5 (4) ◽

pp. 121 ◽

Cited By ~ 1

Author(s):

William Setzer

Keyword(s):

Native Americans ◽

Medicinal Plants ◽

Biological Activities ◽

Herbal Medicines ◽

Black Cohosh ◽

Cimicifuga Racemosa ◽

Traditional Uses ◽

Aromatic And Medicinal Plants ◽

Phytochemical Investigation ◽

Phytochemical Constituents

Background: Native Americans have had a rich ethnobotanical heritage for treating diseases, ailments, and injuries. Cherokee traditional medicine has provided numerous aromatic and medicinal plants that not only were used by the Cherokee people, but were also adopted for use by European settlers in North America. Methods: The aim of this review was to examine the Cherokee ethnobotanical literature and the published phytochemical investigations on Cherokee medicinal plants and to correlate phytochemical constituents with traditional uses and biological activities. Results: Several Cherokee medicinal plants are still in use today as herbal medicines, including, for example, yarrow (Achillea millefolium), black cohosh (Cimicifuga racemosa), American ginseng (Panax quinquefolius), and blue skullcap (Scutellaria lateriflora). This review presents a summary of the traditional uses, phytochemical constituents, and biological activities of Cherokee aromatic and medicinal plants. Conclusions: The list is not complete, however, as there is still much work needed in phytochemical investigation and pharmacological evaluation of many traditional herbal medicines.

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Medicinal importance of Kaempferia galanga L. (Zingiberaceae): A comprehensive review

Journal of Herbmed Pharmacology ◽

10.34172/jhp.2021.32 ◽

2021 ◽

Vol 10 (3) ◽

pp. 281-288

Author(s):

Aswin Rafif Khairullah ◽

Tridiganita Intan Solikhah ◽

Arif Nur Muhammad Ansori ◽

Ristag Hamida Hanisia ◽

Gavrila Amadea Puspitarani ◽

...

Keyword(s):

Medicinal Plants ◽

Traditional Medicine ◽

Southeast Asian ◽

Asian Countries ◽

Comprehensive Review ◽

Methanol Extracts ◽

Kaempferia Galanga ◽

Joint Fractures ◽

Treatment Of Diabetes ◽

Southeast Asian Countries

Kaempferia galanga included in the Zingiberaceae family is one of the potential medicinal plants with aromatic rhizome. In traditional medicine in Asian countries, this plant is widely used by local practitioners. This plant is widely cultivated in most Southeast Asian countries such as Cambodia, Vietnam, Malaysia, Thailand, and Indonesia. Ethyl-para-methoxycinnamate and ethyl-cinnamate are found as the main compounds in hexane, dichloromethane, and methanol extracts of K. galanga. This plant is traditionally used as an expectorant, stimulant, diuretic, carminative, and antipyretic remedy. In addition, K. galanga is used for treatment of diabetes, hypertension, cough, asthma, joint fractures, rheumatism, urticaria, vertigo, and intestinal injuries. Therefore, this study aimed to give a sneak peek view on galangal’s ethnobotany, toxicology, pharmacology, and phytochemistry.

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Ethnobotany as a Science of Preserving Traditional Knowledge: Traditional Uses of Wild Medicinal Plants from District Reasi, J&K (Northwestern Himalaya), India

Botanical Leads for Drug Discovery ◽

10.1007/978-981-15-5917-4_13 ◽

2020 ◽

pp. 277-293

Author(s):

Shiekh Marifatul Haq ◽

Bikarma Singh

Keyword(s):

Medicinal Plants ◽

Traditional Knowledge ◽

Traditional Uses

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Contribution a l’ethnobotanique des Warega (Maniema, Kivu, Zaire)

Bothalia ◽

10.4102/abc.v14i3/4.1216 ◽

1983 ◽

Vol 14 (3/4) ◽

pp. 607-611

Author(s):

M. Kitembo

Keyword(s):

Medicinal Plants ◽

Parasitic Diseases ◽

Vernacular Names ◽

Traditional Uses ◽

Reference Collection ◽

Domestic Use ◽

The University

CONTRIBUTION TO THE ETHNOBOTANY OF THE WAREGA (MANIEMA, KIVU, ZAIRE) As a result of the particular social positions held by the grandfather and aunt of the author, very detailed information about the traditional uses of plants in Maniema could be collected. All the information obtained is supported by a herbarium reference collection deposited in the Herbarium of the University of Lubumbashi (LSHI), together with one or several vernacular names. The information can be grouped on the basis of four main types of utilization, namely plants used as food (seeds and oleaginous nuts, amylaceous fruits and flowers, leaves, berries.); medicinal plants (parasitic diseases, gynaecology, obstetrics, etc.); plants for domestic use (tools, mats, textiles, dyes and other uses).

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