The invasiveness of cardiopulmonary bypass to the whole body in lung transplantation

2013 ◽  
Vol 61 (S 01) ◽  
Author(s):  
K Sato ◽  
C Knosalla ◽  
R Yeter ◽  
M Tsuchida ◽  
R Hetzer
Keyword(s):  
Cardiopulmonary Bypass ◽  
Lung Transplantation ◽  
Whole Body

scholarly journals Outcomes of intraoperative extracorporeal membrane oxygenation versus cardiopulmonary bypass for lung transplantation

2015 ◽  
Vol 149 (4) ◽  
pp. 1152-1157 ◽  
Author(s):  
Tiago N. Machuca ◽  
Stephane Collaud ◽  
Olaf Mercier ◽  
Maureen Cheung ◽  
Valerie Cunningham ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Extracorporeal Membrane Oxygenation ◽  
Lung Transplantation ◽  
Membrane Oxygenation

The Wythenshawe Hybrid Circuit for lung transplantation: a previously undescribed circuit for lung transplant

Perfusion ◽  
2019 ◽  
Vol 35 (3) ◽  
pp. 197-201
Author(s):  
Andrew Brazier ◽  
Edward Seville ◽  
Wesley Hesford ◽  
Bryce Pate ◽  
Paul Exton ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Extracorporeal Membrane Oxygenation ◽  
Lung Transplantation ◽  
Lung Transplant ◽  
Transfusion Requirement ◽  
Safety Net ◽  
Membrane Oxygenation ◽  
Hybrid Circuit

Extracorporeal membrane oxygenation is a safe modality of cardiorespiratory support for lung transplantation, with a reduction in coagulopathy and transfusion requirement when compared with cardiopulmonary bypass. In some scenarios, in lung transplantation, there are advantages to the use of cardiopulmonary bypass, which allows cardiac decompression, filtering of embolic air, easy addition and removal of volume, and a means to immediately reintroduce lost blood into circulation. We describe a novel circuit which allows safe and easy switch between modalities without prolonged interruption of flow. This circuit offers a safety net during surgery to minimise the risks influencing the use of extracorporeal membrane oxygenation.

Modulation of Systemic Inflammatory Response after Cardiac Surgery

2005 ◽  
Vol 13 (4) ◽  
pp. 382-395 ◽  
Author(s):  
Shahzad G Raja ◽  
Gilles D Dreyfus
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Inflammatory Response ◽  
Inflammatory Reaction ◽  
Therapeutic Strategies ◽  
Systemic Inflammatory Response ◽  
Whole Body ◽  
Hemodynamic Stability ◽  
Immunomodulatory Agents ◽  
Considerable Research

Cardiac surgery and cardiopulmonary bypass initiate a systemic inflammatory response largely determined by blood contact with foreign surfaces and the activation of complement. It is generally accepted that cardiopulmonary bypass initiates a whole-body inflammatory reaction. The magnitude of this inflammatory reaction varies, but the persistence of any degree of inflammation may be considered potentially harmful to the cardiac patient. The development of strategies to control the inflammatory response following cardiac surgery is currently the focus of considerable research efforts. Diverse techniques including maintenance of hemodynamic stability, minimization of exposure to cardiopulmonary bypass circuitry, and pharmacologic and immunomodulatory agents have been examined in clinical studies. This article briefly reviews the current concepts of the systemic inflammatory response following cardiac surgery, and the various therapeutic strategies being used to modulate this response.

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