scholarly journals Test-Retest of Long Latency Auditory Evoked Potentials (P300) with Pure Tone and Speech Stimuli

2016 ◽  
Vol 21 (02) ◽  
pp. 134-139 ◽  
Author(s):  
Ana Perez ◽  
Karin Ziliotto ◽  
Liliane Pereira
Keyword(s):  
Evoked Potentials ◽  
Auditory Processing ◽  
Pure Tone ◽  
Auditory Evoked Potentials ◽  
Evoked Potential ◽  
Auditory Evoked Potential ◽  
Speech Stimulus ◽  
P300 Latency ◽  
Speech Stimuli ◽  
Long Latency

Introduction Long latency auditory evoked potentials, especially P300, have been used for clinical evaluation of mental processing. Many factors can interfere with Auditory Evoked Potential - P300 results, suggesting large intra and inter-subject variations. Objective The objective of the study was to identify the reliability of P3 components (latency and amplitude) over 4–6 weeks and the most stable auditory stimulus with the best test-retest agreement. Methods Ten normal-hearing women participated in the study. Only subjects without auditory processing problems were included. To determine the P3 components, we elicited long latency auditory evoked potential (P300) by pure tone and speech stimuli, and retested after 4–6 weeks using the same parameters. We identified P300 latency and amplitude by waveform subtraction. Results We found lower coefficient of variation values in latency than in amplitude, with less variability analysis when speech stimulus was used. There was no significant correlation in latency measures between pure tone and speech stimuli, and sessions. There was a significant intrasubject correlation between measures of latency and amplitude. Conclusion These findings show that amplitude responses are more robust for the speech stimulus when compared with its pure tone counterpart. The P300 indicated stability for latency and amplitude measures when the test-retest was applied. Reliability was higher for amplitude than for latency, with better agreement when the pure tone stimulus was used. However, further research with speech stimulus is needed to clarify how these stimuli are processed by the nervous system.

scholarly journals Parameters for Applying the Brainstem Auditory Evoked Potential with Speech Stimulus: Systematic Review

2017 ◽  
Vol 22 (04) ◽  
pp. 460-468 ◽  
Author(s):  
Luísa Gabriel ◽  
Luíza Vernier ◽  
Maria Ferreira ◽  
Adriana Silveira ◽  
Márcia Machado
Keyword(s):  
Systematic Review ◽  
Evoked Potentials ◽  
Brain Stem ◽  
Auditory Evoked Potentials ◽  
Evoked Potential ◽  
Sampling Rate ◽  
Presentation Rate ◽  
Auditory Evoked Potential ◽  
Speech Stimulus ◽  
Brainstem Auditory Evoked Potential

Introduction Studies using the Brainstem Auditory Evoked Potential with speech stimulus are increasing in Brazil, and there are divergences between the methodologies used for testing. Objectives To analyze the parameters used in the study of the Brainstem Auditory Evoked Potentials with speech stimulus. Data Synthesis The survey was performed using electronic databases. The search strategy was as follows: “Evoked potentials, auditory” OR “Brain stem” OR “Evoked potentials, auditory, brain stem” AND “Speech.” The survey was performed from June to July of 2016. The criteria used for including articles in this study were: being written in Portuguese, English or Spanish; presenting the description of the testing parameters and the description of the sample. In the databases selected, 2,384 articles were found, and 43 articles met all of the inclusion criteria. The predominance of the following parameters was observed to achieve the potential during study: stimulation with the syllable /da/; monaural presentation with greater use of the right ear; intensity of 80 dB SPL; vertical placement of electrodes; use of in-ear headphones; patient seated, distracted in awake state; alternating polarity; use of speech synthesizer software for the elaboration of stimuli; presentation rate of 10.9/s; and sampling rate of 20 kHz. Conclusions The theme addressed in this systematic review is relatively recent. However, the results are significant enough to encourage the use of the procedure in clinical practice and advise clinicians about the most used procedures in each parameter.

scholarly journals Auditory Evoked Potentials P50: Pure-tones vs Clicks. There is a Similar Supression?

2020 ◽  
pp. 32-39
Author(s):  
PhD M.D, Seidel Guerra López ◽  
M.D, María de Los A. Pedroso Rodríguez ◽  
M.D, Diego Cantero ◽  
Gilvan Aguiar da Silva
Keyword(s):  
Evoked Potentials ◽  
Pure Tone ◽  
Auditory Evoked Potentials ◽  
Sound Pressure ◽  
Evoked Potential ◽  
Stimulus Frequency ◽  
Auditory Evoked Potential ◽  
Pure Tones ◽  
Middle Latency ◽  
The Brain

Objective: Clinical application of middle-latency auditory evoked potential (MLAEPs) has been increasing, highlighting the importance of understanding the nature of P50, a component of middle-latency auditory evoked potential. We manipulated stimulus frequency bands in auditory stimuli in order to investigate the nature of P50 in human auditory evoked potentials. Methods: Two paradigms have been used to obtain P50: one is a conditioning /testing paradigm in which paired of pure tone (1000Hz) are delivered, and the other was presented paired of clicks, both with an intensity of 60 dB sound pressure level above the auditory threshold. A total of 30 healthy volunteers were recruited for this study among Center of genetic engineering (fifteen man and fifteen women, mean age of 36, 5). All without consumption of caffeine, cigarettes and drugs. Results: No statistically significant differences occurred between the P50 amplitudes and latencies for the pure tone and those for the clicks. Conclusions: Our present results indicate that P50 in humans may reflect a feed-forward mechanism of the brain where a preceding stimulus drives sensory gating mechanisms in preparation for a second stimulus, but the contained frequency doesn't influence on the P50. Both types (tones or clicks) can be used in the exploration of patient with this evoked potential.

New possibility for measuring the cortical auditory evoked potentials: the HEARLab

2014 ◽  
Vol 155 (38) ◽  
pp. 1524-1529
Author(s):  
Ádám Bach ◽  
Ferenc Tóth ◽  
Vera Matievics ◽  
József Géza Kiss ◽  
József Jóri ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Evoked Potentials ◽  
Auditory System ◽  
Hearing Aids ◽  
Pure Tone ◽  
Auditory Evoked Potentials ◽  
Normal Hearing ◽  
Speech Stimuli ◽  
Novel Method ◽  
Cortical Auditory Evoked Potentials

Introduction: Cortical auditory evoked potentials can provide objective information about the highest level of the auditory system. Aim: The purpose of the authors was to introduce a new tool, the “HEARLab” which can be routinely used in clinical practice for the measurement of the cortical auditory evoked potentials. In addition, they wanted to establish standards of the analyzed parameters in subjects with normal hearing. Method: 25 adults with normal hearing were tested with speech stimuli, and frequency specific examinations were performed utilizing pure tone stimuli. Results: The findings regarding the latency and amplitude analyses of the evoked potentials confirm previously published results of this novel method. Conclusions: The HEARLAb can be a great help when performance of the conventional audiological examinations is complicated. The examination can be performed in uncooperative subjects even in the presence of hearing aids. The test is frequency specific and does not require anesthesia. Orv. Hetil., 2014, 155(38), 1524–1529.

Informational Masking Effects of Speech Versus Nonspeech Noise on Cortical Auditory Evoked Potentials

2021 ◽  
Vol 64 (10) ◽  
pp. 4014-4029
Author(s):  
Kathy R. Vander Werff ◽  
Christopher E. Niemczak ◽  
Kenneth Morse
Keyword(s):  
Auditory Processing ◽  
Auditory Evoked Potentials ◽  
Spectral Characteristics ◽  
Auditory Evoked Potential ◽  
Informational Masking ◽  
Neural Encoding ◽  
Speech Stimuli ◽  
Typical Morphology ◽  
Cortical Auditory Evoked Potentials ◽  
Speech Information

Purpose Background noise has been categorized as energetic masking due to spectrotemporal overlap of the target and masker on the auditory periphery or informational masking due to cognitive-level interference from relevant content such as speech. The effects of masking on cortical and sensory auditory processing can be objectively studied with the cortical auditory evoked potential (CAEP). However, whether effects on neural response morphology are due to energetic spectrotemporal differences or informational content is not fully understood. The current multi-experiment series was designed to assess the effects of speech versus nonspeech maskers on the neural encoding of speech information in the central auditory system, specifically in terms of the effects of speech babble noise maskers varying by talker number. Method CAEPs were recorded from normal-hearing young adults in response to speech syllables in the presence of energetic maskers (white or speech-shaped noise) and varying amounts of informational maskers (speech babble maskers). The primary manipulation of informational masking was the number of talkers in speech babble, and results on CAEPs were compared to those of nonspeech maskers with different temporal and spectral characteristics. Results Even when nonspeech noise maskers were spectrally shaped and temporally modulated to speech babble maskers, notable changes in the typical morphology of the CAEP in response to speech stimuli were identified in the presence of primarily energetic maskers and speech babble maskers with varying numbers of talkers. Conclusions While differences in CAEP outcomes did not reach significance by number of talkers, neural components were significantly affected by speech babble maskers compared to nonspeech maskers. These results suggest an informational masking influence on neural encoding of speech information at the sensory cortical level of auditory processing, even without active participation on the part of the listener.

scholarly journals Features of use of evoked potential method on children with epilepsy of pre- and puberty age-old period

2021 ◽  
pp. 19-21
Author(s):  
Maryna Gekova ◽  
Lyudmyla Tantsura
Keyword(s):  
Pilot Study ◽  
Evoked Potentials ◽  
Visual Evoked Potentials ◽  
Evoked Potential ◽  
Potential Method ◽  
Auditory Evoked Potential ◽  
Long Latency ◽  
Interaural Differences ◽  
Patients With Epilepsy

This paper of the usage of the evoked potential method is studied, in patients with epilepsy. A brief description of the method is described. A pilot study of auditory long-latency and visual on the outbreak of evoked potential was carried out in 19 children with various forms of epilepsy, who are in long-term remission, and also with pharmacoresistant seizures. It was found that the visual evoked potentials are more indicative than auditory evoked potential. In most cases, a decrease in the amplitude and lengthening of evoked potentials latencies was revealed. Moreover, in the presence of focal changes, interocular or interaural differences were recorded. In that way, it is necessary to study the features of evoked potentials in children with epilepsy, study evoked potentials in the course of treatment in order to predict the course of the disease and the effectiveness of the therapy. The obtained data will serve as the basis for further research of the evoked potential method in children with epilepsy.

scholarly journals Going Beyond Rote Auditory Learning: Neural Patterns of Generalized Auditory Learning

2021 ◽  
pp. 1-20
Author(s):  
Shannon L. M. Heald ◽  
Stephen C. Van Hedger ◽  
John Veillette ◽  
Katherine Reis ◽  
Joel S. Snyder ◽  
...  
Keyword(s):  
Speech Perception ◽  
Auditory Processing ◽  
Auditory Evoked Potentials ◽  
Auditory Evoked Potential ◽  
Rote Learning ◽  
Neural Responses ◽  
Auditory Learning ◽  
New Words ◽  
Long Latency ◽  
Pattern Variability

Abstract The ability to generalize across specific experiences is vital for the recognition of new patterns, especially in speech perception considering acoustic–phonetic pattern variability. Indeed, behavioral research has demonstrated that listeners are able via a process of generalized learning to leverage their experiences of past words said by difficult-to-understand talker to improve their understanding for new words said by that talker. Here, we examine differences in neural responses to generalized versus rote learning in auditory cortical processing by training listeners to understand a novel synthetic talker. Using a pretest–posttest design with EEG, participants were trained using either (1) a large inventory of words where no words were repeated across the experiment (generalized learning) or (2) a small inventory of words where words were repeated (rote learning). Analysis of long-latency auditory evoked potentials at pretest and posttest revealed that rote and generalized learning both produced rapid changes in auditory processing, yet the nature of these changes differed. Generalized learning was marked by an amplitude reduction in the N1–P2 complex and by the presence of a late negativity wave in the auditory evoked potential following training; rote learning was marked only by temporally later scalp topography differences. The early N1–P2 change, found only for generalized learning, is consistent with an active processing account of speech perception, which proposes that the ability to rapidly adjust to the specific vocal characteristics of a new talker (for which rote learning is rare) relies on attentional mechanisms to selectively modify early auditory processing sensitivity.

Auditory Evoked Potentials in Audiometric Assessment of Compensation and Medicolegal Patients

1986 ◽  
Vol 95 (5) ◽  
pp. 514-519 ◽  
Author(s):  
Martyn Hyde ◽  
Noriaki Matsumoto ◽  
Peter Alberti ◽  
Yao-Li Li
Keyword(s):  
Evoked Potentials ◽  
Pure Tone ◽  
Clinical Utility ◽  
Auditory Evoked Potentials ◽  
Evoked Potential ◽  
Pure Tone Audiogram ◽  
Middle Latency Response ◽  
Widespread Implementation ◽  
Latency Response ◽  
Almost All

The clinical utility of auditory evoked potentials for validation of the pure tone audiogram in adult compensation claimants and medicolegal patients is examined. Large sample comparisons of evoked potential and conventional pure tone thresholds showed that the slow vertex response can estimate true hearing levels within 10 dB in almost all patients. Given adequate tester skills, it is the tool of choice, and it merits more widespread implementation. Properly used, it can improve and abbreviate the assessment battery for detection and quantification of nonorganic hearing loss. The 40-Hz middle latency response is useful as a secondary tool, but at present, cochlear nerve and brain stem potentials have limited audiometric value in this population.

High-frequency Components of Auditory Evoked Potentials Are Detected in Responsive but Not in Unconscious Patients

2005 ◽  
Vol 103 (5) ◽  
pp. 944-950 ◽  
Author(s):  
Bertram Scheller ◽  
Gerhard Schneider ◽  
Michael Daunderer ◽  
Eberhard F. Kochs ◽  
Bernhard Zwissler
Keyword(s):  
Evoked Potentials ◽  
General Anesthesia ◽  
High Frequency ◽  
Auditory Evoked Potentials ◽  
Evoked Potential ◽  
Auditory Evoked Potential ◽  
General Anesthetics ◽  
Frequency Bands ◽  
Time Frequency ◽  
Frequency Components

Background The dose-dependent suppression of midlatency auditory evoked potentials by general anesthetics has been proposed to measure depth of anesthesia. In this study, perioperatively recorded midlatency auditory evoked potentials were analyzed in a time-frequency space to identify significant changes induced by general anesthesia. Methods Perioperatively recorded auditory evoked potentials of 19 patients, recorded at varying levels of anesthesia, were submitted to a multiscale analysis using the wavelet analysis. Energy contents of the signal were calculated in frequency bands 0-57.1 Hz, 57.1-114.3 Hz, 114.3-228.6 Hz, and 228.6-457.1 Hz. A Friedman test and a Dunn multiple comparisons test were performed to identify significant differences. Results Statistical evaluation showed a highly significant decrease of the wavelet energies for the frequency bands 57.1-114.3 Hz (P < 0.0001), 114.3-228.6 Hz (P < 0.0001), and 228.6-457.1 Hz (P < 0.0001) for the measuring points representing deep general anesthesia. This decrease is accompanied by a decrease in the wavelet energy of the frequency band 0-57.1 Hz of no statistical significance (P = 0.021) (level of significance set to P = 0.01). The changes are most prominent in the poststimulus interval between 10 and 30 ms. Conclusions This study describes the presence of high-frequency components of the auditory evoked potential. The amount of these components is higher during responsiveness when compared to unconsciousness. Temporal localization of the high-frequency components within the auditory evoked potential shows that they represent a response to the auditory stimulus. Further studies are required to identify the source of these high-frequency components.

scholarly journals Abnormalities in auditory evoked potentials of 75 patients with Arnold-Chiari malformations types I and II

2006 ◽  
Vol 64 (3a) ◽  
pp. 619-623 ◽  
Author(s):  
Paulo Sergio A. Henriques Filho ◽  
Riccardo Pratesi
Keyword(s):  
Evoked Potentials ◽  
Auditory Evoked Potentials ◽  
Evoked Potential ◽  
Amplitude Ratio ◽  
Auditory Evoked Potential ◽  
Type I ◽  
Auditory Pathways ◽  
Degree Of Severity ◽  
Chiari Malformations

OBJECTIVE: To evaluate the frequency and degree of severity of abnormalities in the auditory pathways in patients with Chiari malformations type I and II. METHOD: This is a series-of-case descriptive study in which the possible presence of auditory pathways abnormalities in 75 patients (48 children and 27 adults) with Chiari malformation types I and II were analyzed by means of auditory evoked potentials evaluation. The analysis was based on the determination of intervals among potentials peak values, absolute latency and amplitude ratio among potentials V and I. RESULTS: Among the 75 patients studied, 27 (36%) disclosed Arnold-Chiari malformations type I and 48 (64%) showed Arnold-Chiari malformations type II. Fifty-three (71%) of these patients showed some degree of auditory evoked potential abnormalities. Tests were normal in the remaining 22 (29%) patients. CONCLUSION: Auditory evoked potentials testing can be considered a valuable instrument for diagnosis and evaluation of brain stem functional abnormalities in patients with Arnold-Chiari malformations type I and II. The determination of the presence and degree of severity of these abnormalities can be contributory to the prevention of further handicaps in these patients either through physical therapy or by means of precocious corrective surgical intervention.

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