Acute Sensory Neuronopathy following Enterovirus Infection in a 3-Year-Old Girl

2017 ◽  
Vol 48 (03) ◽  
pp. 190-193 ◽  
Author(s):  
Chih-Chin Chiu ◽  
Chen-Ya Yang ◽  
Tsui-Fen Yang ◽  
Kon-Ping Lin ◽  
Shou-Hsien Huang ◽  
...  
Keyword(s):  
Sensory Nerve ◽  
Lower Limbs ◽  
Enterovirus Infection ◽  
Sensory Neuronopathy ◽  
System Disease ◽  
Sensory Axons ◽  
Comprehensive Knowledge ◽  
Sensory Nerve Action ◽  
Posterior Pharynx ◽  
Patient’S History

AbstractAcute sensory neuronopathy (SNN) is a rapidly developing peripheral nervous system disease that primarily affects sensory neurons in the dorsal root ganglion or trigeminal ganglion, leading to the impairment of sensory axons. SNN is notably uncommon in childhood; only three cases of childhood or adolescent SNN have been reported to date. Moreover, SSN has never been reported in association with enterovirus infection. Here, we report the case of a 3-year-old girl who was initially diagnosed with enterovirus infection based on the presentation of fevers, rashes on all extremities, and ulceration over the posterior pharynx. Nine days later, she presented with ataxic and wide-based gait and dysmetria affecting the extremities, with an absence of sensory nerve action potentials in the upper and lower limbs. The patient was diagnosed with acute SNN based on the criteria developed by Camdessanché et al in 2009. To our knowledge, this is the youngest case of SNN reported to date. In addition, this case reveals that enterovirus infection can be associated with acute SNN in children in rare cases. Accurate diagnosis relies on clinical suspicion, comprehensive knowledge of the patient's history, and careful characterization of abnormal findings in electrodiagnostic studies.

scholarly journals Electrophysiological diagnosis using sensory nerve action potential for the intraforaminal and extraforaminal L5 nerve root entrapment

2012 ◽  
Vol 22 (4) ◽  
pp. 833-839 ◽  
Author(s):  
Muneharu Ando ◽  
Tetsuya Tamaki ◽  
Mamoru Kawakami ◽  
Akihito Minamide ◽  
Yukihiro Nakagawa ◽  
...  
Keyword(s):  
Action Potential ◽  
Nerve Root ◽  
Sensory Nerve ◽  
Sensory Nerve Action Potential ◽  
Nerve Action ◽  
Sensory Nerve Action ◽  
Nerve Root Entrapment

scholarly journals An infantile alantoaxial dislocation with patent foramen ovale managed with titanium cabling and allogenic bone grafts

2018 ◽  
Vol 10 (1) ◽  
Author(s):  
Seidu A. Richard ◽  
Zhi Gang  Lan ◽  
Xiao Yang ◽  
Siqing Huang
Keyword(s):  
Action Potentials ◽  
Patent Foramen Ovale ◽  
Early Stage ◽  
Sensory Nerve ◽  
Odontoid Process ◽  
Bone Destruction ◽  
Lower Limbs ◽  
Foramen Ovale ◽  
Compound Muscle Action Potentials ◽  
Patient Reported

Atlantoaxial dislocation is a disorder that is characterized with loss of stability of the atlas and axis (C1-C2) with consequential loss of usual articulation. Although this condition is very common, no one has reported a case as young as our patients. We present a 7-month infant with bilateral paralysis of the lower limbs for four (4) months with no history of trauma. Computer tomographic (CT-scan) imaging revealed alantoaxial dislocation with severe cervical spinal cord compression. The odontoid process is displaced outwardly with no bone destruction. Doppler echocardiogram done revealed patent foramen ovale. Thorough physical examination as well as radiological evaluation revealed no feather malformations. Electrophysio - logical studies reveal normal compound muscle action potentials (CMAP) and sensory nerve action potentials (SNAPs) in all the limbs. Electromyography (EMG) also revealed normal nerves in the limbs and the trunk. We attained a stable fusion and anatomical reduction using a posterior titanium wire and an iliac bone graft harvested from his mother. This is the youngest patient reported in literature. Infantile alantoaxial dislocation should be managed at early stage to prevent long-term neurologic disorders.

scholarly journals Carpal tunnel syndrome: long-term nerve conduction studies in 261 hands

2009 ◽  
Vol 67 (1) ◽  
pp. 69-73 ◽  
Author(s):  
Dante Guilherme Velasco Hardoim ◽  
Guilherme Bueno de Oliveira ◽  
João Aris Kouyoumdjian
Keyword(s):  
Carpal Tunnel Syndrome ◽  
Carpal Tunnel ◽  
Nerve Conduction ◽  
Sensory Nerve ◽  
Nerve Conduction Studies ◽  
Sensory Nerve Action ◽  
Tunnel Syndrome ◽  
The Mean ◽  
Compound Action

OBJECTIVE: To compare a long-term carpal tunnel syndrome (CTS) on nerve conduction studies (NCS) in hands treated non-surgically. METHOD: We retrospectively selected 261 symptomatic CTS hands (166 patients), all of them confirmed by NCS. In all cases, at least 2 NCS were performed in an interval greater than 12 months. Cases with associated polyneuropathy were excluded. NCS parameters for CTS electrodiagnosis included a sensory conduction velocity (SCV) <46.6 m/s (wrist to index finger, 14 cm) and distal motor latency (DML) >4.25 ms (wrist to APB, 8 cm). RESULTS: 92.8% were women; mean age was 49 years (20-76); the mean interval between NCS was 47 months (12-150). In the first exam, the median sensory nerve action potential (SNAP) and the compound action muscular potential were absent in 9.8% and 1.9%, respectively. In the second/last exam, SCV worsened in 54.2%, remained unchanged in 11.6% and improved in 34.2%. SNAP amplitude worsened in 57.7%, remained unchanged in 13.1% and improved in 29.2%. DML worsened in 52.9%, remained unchanged in 7.6% and improved in 39.5%. Overall, NCS parameters worsened in 54.9%, improved in 34.3% and remained unchanged in 10.8%. CONCLUSION: Long-term changing in NCS of CTS hands apparently were not related to clinical symptomatology and could lead to some difficulty in clinical correlation and prognosis. Aging, male gender and absent SNAP were more related to NCS worsening, regardless the mean interval time between the NCS.

Close relationship between cardiovagal function and sural sensory nerve action potential in type 2 diabetes

2019 ◽  
Vol 130 (7) ◽  
pp. 1160-1165
Author(s):  
Yun-Ru Lai ◽  
Chih-Cheng Huang ◽  
Wen-Chan Chiu ◽  
Rue-Tsuan Liu ◽  
Nai-Wen Tsai ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Action Potential ◽  
Sensory Nerve ◽  
Sensory Nerve Action Potential ◽  
Nerve Action ◽  
Close Relationship ◽  
Sensory Nerve Action

scholarly journals Gait Rehabilitation Device in Central Nervous System Disease: A Review

2011 ◽  
Vol 2011 ◽  
pp. 1-14 ◽  
Author(s):  
Kazuya Kubo ◽  
Takanori Miyoshi ◽  
Akira Kanai ◽  
Kazuhiko Terashima
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Central Nervous System Disease ◽  
Gait Training ◽  
Lower Limbs ◽  
Nervous System Disease ◽  
Gait Rehabilitation ◽  
System Disease ◽  
Physical Burden ◽  
Rehabilitation Devices

Central nervous system diseases cause the gait disorder. Early rehabilitation of a patient with central nervous system disease is shown to be benefit. However, early gait training is difficult because of muscular weakness and those elderly patients who lose of leg muscular power. In the patient's walking training, therapists assist the movement of patient's lower limbs and control the movement of patient's lower limbs. However the assistance for the movement of the lower limbs is a serious hard labor for therapists. Therefore, research into and development of various gait rehabilitation devices is currently underway to identify methods to alleviate the physical burden on therapists. In this paper, we introduced the about gait rehabilitation devices in central nervous system disease.

scholarly journals Normal neurophysiologic parameters of the median nerve among adult healthy Sudanese population

2020 ◽  
Vol 10 (4) ◽  
pp. 136-141
Author(s):  
Mohammed Salah Elmagzoub ◽  
Ahmed Hassan Ahmed ◽  
Hussam M A Hameed
Keyword(s):  
Action Potential ◽  
Median Nerve ◽  
Conduction Velocity ◽  
Nerve Conduction ◽  
Compound Muscle Action Potential ◽  
Motor Nerve ◽  
Sensory Nerve ◽  
Peak Latency ◽  
Muscle Action Potential ◽  
Sensory Nerve Action

Background: Nerve conduction studies (NCSs) help in delineating the extent distribution of neural lesion, and the diagnosis of peripheral nerve disorders. Because normative nerve conduction parameters were not yet established in Sudan EMG laboratories, this study aims towards having our own reference values, as we are using the American and British parameters. This will allow avoiding the discrepancies that might be induced by many factors. Methods: NCSs were performed in 200 Median nerves of 100 adult healthy Sudanese subjects using standardized techniques. Results: The median SNAP (sensory nerve action potential) values were as follows: distal latency, 2.6±3 ms with a range of (2.3-2.9); peak latency, 3.5±0.5 ms (3.0-4.0); amplitude, 47.7±18.0μV (29.7-65.7); conduction velocity, 53.0±7.8 m/s (45.2-60.8). The following values were obtained for the Median nerve CMAP (compound muscle action potential) at wrist stimulation: distal latency, 3.5±0.5 ms with a range of (3.0-4.0); peak latency, 9.4± 1.0 ms (8.4-10.4); duration, 5.9±0.9 ms (5.0-6.8); amplitude, 12.3±2.5 mV (9.8-14.8); area, 43.0±10.4 mVms (32.6-53.4); conduction velocity, 63.6±6.2 m/s (57.4-69.8). The F wave was 28.4±1.8 ms (26.6-30.2). Conclusion: The overall mean sensory and motor nerve conduction parameters for the tested nerve compared favorably with the existing literature with some discrepancies that were justified.

scholarly journals Sciatic neuropathy with preserved sensory nerve action potentials, a case series

2020 ◽  
Vol 1 (1) ◽  
Author(s):  
Matthew Ritch ◽  
Omer Suhaib ◽  
Yuebing Li
Keyword(s):  
Action Potentials ◽  
Sensory Nerve ◽  
Case Series ◽  
Normal Range ◽  
Single Institution ◽  
Lumbosacral Radiculopathy ◽  
Sciatic Neuropathy ◽  
Nerve Action ◽  
Sensory Nerve Action ◽  
Sensory Fibers

Background: Sciatic neuropathy is differentiated from lumbosacral radiculopathy based on the finding of abnormal sensory nerve action potentials (SNAPs). Cases of sciatic neuropathy with intact SNAPS have not been well described. Methods: A retrospective analysis of 12 patients with sciatic neuropathy in a single institution. Results: We describe 12 patients in whom a sciatic neuropathy was diagnosed based on a combination of history, physical exam, radiological and electrodiagnostic (EDX) findings. Lower extremity SNAPs were found to be within normal range in all patients, although SNAP amplitude asymmetry between both sides was observed in 3. Included patients were young (mean age of 40.3 years) and mostly female (9 patients). Conclusions: Sciatic neuropathy may occur with a relative sparing of sensory fibers. Recognition of this group of patients should help to avoid making a misdiagnosis of lumbosacral radiculopathy.

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