Once-weekly dulaglutide (DU) vs. insulin glargine in the control of fasting serum glucose and hypoglycaemia rate in the first 20 weeks in patients with type 2 diabetes mellitus on metformin and glimepiride

2017 ◽  
Vol 12 (S 01) ◽  
pp. S1-S84
Author(s):  
E Jodar ◽  
R Gentilella ◽  
M Cunha ◽  
J Reviriego ◽  
B Schinzel ◽  
...  
2012 ◽  
Vol 6 (2) ◽  
pp. 42-49
Author(s):  
Rayah Sulaiman Baban ◽  
Zeina Ismael Ibrahem ◽  
Isam Noori Al-Karawi

o study the association of serum leptin and glucose/leptin ratio with microalbuminuria in patients with type 2 diabetes mellitus at different durations, and to predict their effect on their renal function. A case control study was conducted in the International Diabetic Center at Al-Mustansiryia University in Baghdad-Iraq from 1st September 2008 to the 30th of July 2010. One hundred and eight male patients with type 2 diabetes mellitus (DM) were introduced in this study. Fifty three healthy subjects were used as a control. Fasting serum glucose, insulin, leptin, urea, creatinine and body mass index were estimated in both patient and control groups. Fifty three 49.07% out of 108 were diabetic for ≤2 years, while 55 patient 50.93% were diabetic >2 years. All patients were obese while healthy control subjects were not. Fasting serum glucose, insulin and leptin levels were found elevated in patients group while in control group their levels were found within normal range. Both urea and creatinine were also within the normal range for patients and control groups. Level of albumin in urine of patients with diabetes mellitus for ≤ 2years was found normal while in those with 3 to 6 or more than 6 years of DM, level of urinary albumin was found within the micro rang. A positive correlation with highly significant p value (<0.01) was found between patients (≤ 2 years and >2 years) serum leptin, glucose/leptin ratio and microalbuminuria. Conclusions: a strong association was found between serum leptin and glucose/leptin ratio with microalbuminuria in type 2 diabetic patients which can be used to predict the efficiency of their renal function at different durations and can be used as additional marker for the diagnosis of early stage of nephropathy.


2018 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Ali Tarighat-Esfanjani ◽  
Habib Fallahnejad ◽  
Hosein Omidi ◽  
Mohammad Asghari Jafarabadi ◽  
Mehran Mesgari Abbasi ◽  
...  

2018 ◽  
Vol 20 (12) ◽  
pp. 2894-2898 ◽  
Author(s):  
Brian M. Frier ◽  
Wolfgang Landgraf ◽  
Mei Zhang ◽  
Geremia B. Bolli ◽  
David R. Owens

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Theerawut Klangjareonchai ◽  
Chulaporn Roongpisuthipong

Objective. To determine the effects ofTinospora crispaon serum glucose and insulin levels in healthy subjects and patients with type 2 diabetes mellitus.Method. Serum from 10 healthy subjects and 10 diabetic participants, who had fasted overnight, were obtained every 30–60 minutes during the 3 hours of continued fasting and during the 3 hours after ingestion of 75 g of glucose with or without ingestion of 125 or 250 g ofTinospora crispadry powder capsule. Glucose and Insulin levels were analyzed and the areas under the curve for mean serum glucose and insulin levels were calculated.Result. The areas under the curve of mean serum glucose and insulin levels in both healthy and diabetic participants were not significantly different between with or withoutTinospora crispadry powder capsule. In diabetic participants the area under the curve of glucose was slightly lesser when 250 mg ofTinospora crispawas ingested, but not reaching statistical significance (478 and 444 mg min/ml, resp.,P=0.57).Conclusion. The results suggest thatTinospora crispaingestion cannot affect serum glucose and insulin levels in healthy subjects or patients with type 2 diabetes mellitus.


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