Flexible Two-Stage Designs: An Overview
2001 ◽
Vol 40
(02)
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pp. 117-121
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Keyword(s):
P Values
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AbstractIn this overview we introduce the basic ideas behind a new flexible approach in sequential designs. The different concepts based on two-stage combination tests and conditional error functions are brought together. We sketch the construction of p-values, confidence intervals, and median unbiased estimates. Finally, recursive combination tests are introduced which extend the flexibility to the choice of the number of interim analyses.