Role of Lactoferrin in Neonates and Infants: An Update

2018 ◽  
Vol 35 (06) ◽  
pp. 561-565 ◽  
Author(s):  
Alberto Dall'Agnola ◽  
Daniel Tomé ◽  
David Kaufman ◽  
Elena Tavella ◽  
Marta Pieretto ◽  
...  

AbstractLactoferrin is one of the most represented and important bioactive proteins in human and mammal milk. In humans, lactoferrin is responsible for several actions targeting anti-infective, immunological, and gastrointestinal domains in neonates, infants, and young children. Evidence-based data vouch for the ability of supplemented lactoferrin to prevent sepsis and necrotizing enterocolitis in preterm infants and to reduce the burden of morbidity related to gastrointestinal and respiratory pathogens in young children. However, several issues remain pending regarding answers and clarification related to quality control, correct intakes, optimal schedules and schemes of supplementations, interactions with probiotics, and different types of milk and formulas. This review summarizes the current evidence regarding lactoferrin and discusses the areas in need of further guidance prior to the adoption of strategies that include a routine use of lactoferrin in neonates and young children.

PEDIATRICS ◽  
1966 ◽  
Vol 38 (3) ◽  
pp. 373-374
Author(s):  
WILLIAM A. SILVERMAN

THE special position of infants and young children as subjects in therapeutic and non-therapeutic investigations is highlighted by recently renewed emphasis on the need to obtain formal consent, when (in the words of a National Institutes of Health memorandum) "procedures deviate from accepted medical practice." Who should act for the very young patient by giving consent based on informed understanding? Most codes for investigators specify that consent may be given only by parents or guardians. In these circumstances parents and guardians are forced into the role of arbiters required to make exceptionally difficult judgments in situations which increase in complexity each day that our knowledge increases.


2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Marion Leslie Roche ◽  
Hilary M Creed‐Kanashiro ◽  
Irma Tuesta ◽  
Harriet V Kuhnlein

2020 ◽  
Vol 47 (1) ◽  
pp. 10-35
Author(s):  
Clodagh Tait

Wet-nursing and fosterage were widely used in early modern Ireland. Despite the difficulties of reconstructing practices surrounding the nourishment and care of infants and young children, the limited surviving sources provide some evidence for the practical arrangements involved, the role of these practices in extending families and creating long-lasting ties of ‘fictive kinship’, the emotional and economic connections they forged and deeply held concerns that they might inspire and extend political disloyalty and disaffection. While fosterage is mostly associated with Gaelic communities, by the sixteenth century, a distinct brand of fosterage was significant to Old English families as well. New English and Protestant families also increasingly participated in networks referred to as fosterage, and references in the 1641 depositions testify to the degree to which these practices linked settlers and natives and the horror inspired by their abandonment.


1992 ◽  
Vol 4 (3) ◽  
pp. 375-383 ◽  
Author(s):  
Wendy Phillips ◽  
Simon Baron-Cohen ◽  
Michael Rutter

AbstractOne reason for looking at a person's eyes may be to diagnose their goal, because a person's eye direction reliably specifies what they are likely to act upon next. We report an experiment that investigates whether or not young normal infants use eye contact for this function. We placed them in situations in which the adult's action toward them was either ambiguous or unambiguous in its goal. Results showed that the majority of normal infants and young children with mental handicap made instant eye contact immediately following the ambiguous action but rarely after the unambiguous action. Young children with autism, in contrast, made eye contact equally (little) in both conditions. These results are discussed in relation to the function of eye contact, to our understanding of infant cognition, and to the theory of mind hypothesis of autism.


Sign in / Sign up

Export Citation Format

Share Document