scholarly journals Current Nonoperative Therapeutic Interventions for Lower Gastrointestinal Hemorrhage

2019 ◽  
Vol 33 (01) ◽  
pp. 022-027
Author(s):  
Anna Serur ◽  
Rebecca Rhee ◽  
Joshua Ramjist

AbstractLower gastrointestinal hemorrhage remains a common cause of hospitalization, with significant health care costs. Initial management should include aggressive resuscitation followed by localization of bleeding with nuclear scintigraphy, colonoscopy, or computed tomography (CT) angiography. If bleeding does not resolve spontaneously, expeditious intervention with minimally invasive endoscopic or angiographic methods is necessary with surgical intervention as a last resort.

2014 ◽  
Vol 5 ◽  
pp. BTRI.S14578 ◽  
Author(s):  
Girolamo A. Ortolano ◽  
Barry Wenz

Osteoarthritis (OA) is the most prevalent musculoskeletal disease in humans and domestic animals. It causes significant clinical problems and substantial health care costs. In the absence of disease-modifying medical intervention, therapy is currently restricted to palliative measures prior to surgical intervention. We review the pathogenesis, as well as conservative and emerging restorative therapeutic approaches, including cytokines, stem cells, and platelets. The various methods of platelet concentrate preparations and their reported outcomes are discussed. Data collected from the use of intra-articular platelet therapy (IAPT) in dogs are reviewed, which suggest that this approach may delay or in some cases even obviate the need for surgical intervention.


2011 ◽  
Vol 146 (2) ◽  
pp. 307-312 ◽  
Author(s):  
Neil Bhattacharyya ◽  
Jeff Grebner ◽  
Noel G. Martinson

Objectives. To determine the epidemiology of recurrent acute rhinosinusitis (RARS) and to understand direct health care costs attributable to RARS as a potentially underdiagnosed form of chronic rhinosinusitis. Study Design. Retrospective longitudinal analysis of a medical claims database. Setting. Academic medical center. Methods. Medical claims data (2003–2008) from a large payer database were analyzed. Adult patients with RARS (defined as at least 4 acute rhinosinusitis claims each with a filled oral antibiotic prescription in a 12-month period) were extracted. Sinonasal diagnostic procedures, provider visits, and medical costs were determined. Results. A total of 4588 patients were identified (mean age, 43.5 years; 72.1% female) among 13.1 million patients, for a point prevalence of 0.035%, which remained consistent across years. After 1, 2, and 4 years, 2.4%, 5.4%, and 9.2% of patients subsequently received nasal endoscopy and 11.4%, 23.5%, and 39.9% received paranasal sinus computed tomography, respectively. RARS patients averaged 3.8 antibiotic prescriptions, 5.6 other sinus-related prescriptions, and 5.6 provider visits per year. Total direct health care costs related to RARS averaged $1091/patient-year, with oral antibiotic and nasal prescription costs averaging $210 and $452 per year, respectively. Conclusions. RARS may affect approximately 1 in 3000 adults per year. Despite significant direct health care costs of more than $1000/year per individual patient with RARS, nasal endoscopy and computed tomography are not commonly obtained early after potential diagnosis. RARS is likely an underdiagnosed condition warranting further study.


2019 ◽  
Vol 11 (15) ◽  
pp. 2013-2017 ◽  
Author(s):  
Yiru Wang ◽  
Erin Louwagie ◽  
Daniel Larkin ◽  
Stephanie Sankey ◽  
David R. Boulware ◽  
...  

Group A Streptococcus causes significant health care costs and burdens.


2016 ◽  
Vol 12 (3) ◽  
pp. 197-203
Author(s):  
P Upadhyaya ◽  
C S Agarwal ◽  
A K Karak ◽  
S Karki ◽  
A Pradhan ◽  
...  

Background: Appendicitis is the most common cause of acute abdominal pain requiring surgical intervention. Objective: To determine the relative prevalence of histologically proven acute appendicitis in surgically respected specimens with clinical diagnosis of acute appendicitis and also to find out the rate of occurrence of characinoid tumour as an incidental histologic finding.Methods: It is a retrospective study involving all gross specimens received in the department of pathology over a period of twenty months (1.1.2006 to 31.8.2007). Histologic data on 515 appendicectomy samples (clinically diagnosed as appendicitis) of the total 7295 specimens received over a period of twenty months were retrieved from the archives of department of pathology, with exclusion of appendectomy incidental to another surgical procedure.Results: Appendectomy specimens constituted 7.0% (n=515; M:F 1.1:1) of all surgical pathologic specimens (n=7295) at B.P.K.I.H.S. The breakups of histologic diagnoses are: acute appendicitis with or without periappendicitis and gangrenous change (93.6%, n=482), “receding appendicitis” (5.4%, n=28), and normal histology (1.0%, n= 5). Carcinoid tumours were detected incidentally in three cases (0.58%) out of all appendectomy specimens.Conclusion: Analysis of data revealed a prevalence of 6.99% of histologically proven acute appendicitis in this tertiary health care set up. The rate of occurrence of carcinoid tumour was 0.58%.Health Renaissance 2014;12(3): 197-203


Author(s):  
Stavros Thomopoulos ◽  
Alistair Kent ◽  
Victor Birman ◽  
Rosalina Das ◽  
Brigitte Wopenka ◽  
...  

Musculoskeletal injuries are a common cause of pain and disability, and result in significant health care costs. Rotator cuff injuries, which make up the majority of soft tissue injuries to the upper extremity, commonly require surgical repair to the humeral head. At the rotator cuff, for example, the recurrence of tears to surgically repaired tendons has been reported to be as high as 94% [1]. The most dramatic feature of the failed tendon-to-bone healing scenarios is the lack of a transition zone between the tendon and bone that existed before the injury [2].


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