scholarly journals Use of New Technologies in Implant-Based Breast Reconstruction

2019 ◽  
Vol 33 (04) ◽  
pp. 258-263
Author(s):  
Glyn E. Jones ◽  
Victor A. King ◽  
Aran Yoo ◽  
Amjed Abu-Ghname ◽  
Charalambos K. Rammos
Keyword(s):  
Breast Reconstruction ◽  
New Technologies ◽  
Breast Implant ◽  
Tissue Expander ◽  
Improved Outcomes ◽  
Reconstructive Process ◽  
Perfusion Assessment ◽  
The 1960S ◽  
Instrumental Methods ◽  
Mastectomy Flap

AbstractOutcomes after mastectomy and prosthetic-based breast reconstruction have improved immensely since the development of the first tissue expander and breast implant in the 1960s. One major factor contributing to our improved outcomes over the past two decades is the increasing availability and improvement of perfusion assessment technology. Instrumental methods now exist which allow surgeons to assess tissue viability intraoperatively, and provide actionable, objective data that augments clinical assessment. In this article, the authors detail two commercially available, state-of-the-art technologies that surgeons may use to assist in mastectomy flap assessment and facilitate the reconstructive process.

Prosthetic-Based Breast Reconstruction

2020 ◽  
Author(s):  
Jonathan Nguyen ◽  
Justin Williams ◽  
Albert Losken
Keyword(s):  
Breast Reconstruction ◽  
Breast Implant ◽  
Tissue Expander ◽  
Acellular Dermal Matrix ◽  
Large Cell ◽  
Fat Grafting ◽  
Immediate Reconstruction ◽  
Dermal Matrix ◽  
Prosthetic Reconstruction ◽  
Acellular Dermal

Prosthetic reconstruction is the most popular option for breast reconstruction after mastectomy. There are several different techniques, such as prepectoral versus subpectoral placement, and delayed versus immediate reconstruction, each with their own sets of risks and benefits. With the advent of improved implant technology, acellular dermal matrix, and fat grafting, prepectoral direct to implant has become an accepted and increasingly popular method of reconstruction, with similar to improved complication rates and outcomes as traditional staged tissue expander reconstruction. Prosthetic reconstruction has had some recent controversies, including breast implant associated anaplastic large cell lymphoma and breast implant illness, and many future studies are being directed towards these topics. This review contains 5 figures, and 53 references. Keywords: breast reconstruction, breast implant, acellular dermal matrix, prepectoral reconstruction, tissue expander, fat grafting, capsular contracture, immediate reconstruction, breast implant associated anaplastic large cell lymphoma, breast implant illness

Risk factors for mastectomy flap necrosis following immediate tissue expander breast reconstruction

2014 ◽  
Vol 48 (5) ◽  
pp. 322-326 ◽  
Author(s):  
Alexei S. Mlodinow ◽  
Neil A. Fine ◽  
Nima Khavanin ◽  
John Y. S. Kim
Keyword(s):  
Risk Factors ◽  
Breast Reconstruction ◽  
Tissue Expander ◽  
Flap Necrosis ◽  
Mastectomy Flap

scholarly journals Advances in Biomaterials for Breast Reconstruction

2021 ◽  
Vol 11 (16) ◽  
pp. 7493
Author(s):  
Jun-Ho Park ◽  
Ji-Ung Park ◽  
Hak Chang
Keyword(s):  
Breast Reconstruction ◽  
Breast Tissue ◽  
Breast Implant ◽  
Three Dimensional ◽  
Breast Implants ◽  
3D Bioprinting ◽  
Breast Enlargement ◽  
Liquid Type ◽  
The 1960S ◽  
Solid Implants

Breast cancer is one of the most commonly diagnosed malignancies in women. Along with increasing demands for breast reconstruction, the attention given to the psychological and aesthetic benefits of breast reconstruction has also increased. As breast reconstruction and augmentation demands increase, biomaterials for breast reconstruction are being developed, and the related industry is growing quickly worldwide. Among the various biomaterials used for breast enlargement, breast implants have undergone a remarkable evolution since the 1960s. Despite unsatisfactory results and unexpected complications, research dedicated to achieving an ideal breast implant has progressed. In accordance with attention to tissue engineering, a three-dimensional (3D) bioprinting technique for breast tissue regeneration has emerged to overcome the current limitations of breast biomaterials. Along with solid implants, injectable liquid-type fillers are also part of ongoing studies.

scholarly journals Self-Reported Health Complaints In Women Undergoing Explantation of Breast Implants

2020 ◽  
Author(s):  
Renée M L Miseré ◽  
René R W J van der Hulst
Keyword(s):  
Breast Reconstruction ◽  
Medical Center ◽  
Breast Implant ◽  
Tissue Expander ◽  
Retrospective Chart Review ◽  
Breast Implants ◽  
Good Alternative ◽  
Health Complaints ◽  
Implant Rupture ◽  
Patient Reported

Abstract Background Concerns about the safety of silicone breast implants have existed for years, but a causal relationship between systemic complaints and SBI has not been proven. Nevertheless, women are worried and even request explantation. Objectives This study aimed to review the explantation procedures performed, focusing on patient-reported symptoms preoperatively, the effect of explantation, and the effect of breast reconstruction on these symptoms. Methods A retrospective chart review was performed for patients who had undergone explantation between 2010 and 2020 at Maastricht University Medical Center. Patients excluded were those who had undergone tissue expander (TE) removal, TE to implant exchange, and direct implant exchange. Results More than half of the patients undergoing explantation reported complaints, mostly pain. Some 15% reported suggested implant-related systemic complaints. Breast implant illness (BII) was found to be the fifth most common indication for explantation (11.2%). A history of either allergies or implant rupture resulted in higher odds ratios of having BII (OR=2.1 and 2.1, respectively). Subjective improvement of BII after explantation was reported in about 60%. Conclusions A relatively low prevalence of suggested BII exists among women undergoing explantation; one in nine procedures was performed for this reason. Allergy and implant rupture may increase the likelihood of having BII. About 60% of BII patients experienced an improvement in their complaints after implant removal. Autologous breast reconstruction appears a good alternative. Prospective studies into health complaints and quality of life should be performed to confirm the effectiveness of explantation as a therapy for BII.

scholarly journals Treatment of Congenital Absence of the Mammary Gland

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Masaki Yazawa ◽  
Mika Watanabe ◽  
Masahiro So ◽  
Kazuo Kishi
Keyword(s):  
Mammary Gland ◽  
Breast Reconstruction ◽  
Growth Phase ◽  
Breast Implant ◽  
Donor Site ◽  
Young Patients ◽  
Tissue Expander ◽  
Congenital Absence ◽  
Silicone Breast Implant ◽  
Unaffected Side

Breast reconstruction for breast deformity is significant not only for esthetic purposes but also from a psychological perspective. There have been a few reports on treatment of congenital simple absence of the mammary gland. For patients in puberty, even if they are in the middle of the growth phase, breast reconstruction is very important for the mental quality of life. In our two cases of congenital absence of unilateral mammary gland, breast reconstruction with a tissue expander worked well in terms of esthetic results and the psychological condition of the young patients. In our institute, operative indications are as follows: (1) a girl over 15 years old (this age is selected as breast growth can be determined at this time), (2) no endocrine-related disorders, (3) preoperative examination of breast MRI or US showing the absence or significant hypoplasia of mammary gland, and (4) a wish for breast reconstruction by the patient herself. For patients in the middle of the growth phase, silicone breast implant does not require a donor site and is easily adjustable in terms of volume to match the growth of the breast on the unaffected side by exchanging the silicone breast implant. Therefore, silicone breast implant is a better procedure than skin flaps with their accompanying large donor sites.

scholarly journals Zebrafish as a New Tool in Heart Preservation Research

2021 ◽  
Vol 8 (4) ◽  
pp. 39
Author(s):  
Luciana Da Silveira Cavalcante ◽  
Shannon N. Tessier
Keyword(s):  
New Technologies ◽  
Ex Vivo ◽  
Machine Perfusion ◽  
Life Saving ◽  
First Choice ◽  
Heart Preservation ◽  
End Stage Heart Failure ◽  
Ischemia Tolerance ◽  
The 1960S ◽  
End Stage

Heart transplantation became a reality at the end of the 1960s as a life-saving option for patients with end-stage heart failure. Static cold storage (SCS) at 4–6 °C has remained the standard for heart preservation for decades. However, SCS only allows for short-term storage that precludes optimal matching programs, requires emergency surgeries, and results in the unnecessary discard of organs. Among the alternatives seeking to extend ex vivo lifespan and mitigate the shortage of organs are sub-zero or machine perfusion modalities. Sub-zero approaches aim to prolong cold ischemia tolerance by deepening metabolic stasis, while machine perfusion aims to support metabolism through the continuous delivery of oxygen and nutrients. Each of these approaches hold promise; however, complex barriers must be overcome before their potential can be fully realized. We suggest that one barrier facing all experimental efforts to extend ex vivo lifespan are limited research tools. Mammalian models are usually the first choice due to translational aspects, yet experimentation can be restricted by expertise, time, and resources. Instead, there are instances when smaller vertebrate models, like the zebrafish, could fill critical experimental gaps in the field. Taken together, this review provides a summary of the current gold standard for heart preservation as well as new technologies in ex vivo lifespan extension. Furthermore, we describe how existing tools in zebrafish research, including isolated organ, cell specific and functional assays, as well as molecular tools, could complement and elevate heart preservation research.

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