Melissa officinalis essential oil loaded glycerosomes: preparation and in vitro activity evaluation against herpes labialis (HSV-1)

2019 ◽  
Author(s):  
G Vanti ◽  
V Dourdouni ◽  
D Lazari ◽  
C Panagiotidis ◽  
SG Ntallis ◽  
...  
Keyword(s):  
Essential Oil ◽  
Vitro Activity ◽  
Herpes Labialis ◽  
In Vitro Activity ◽  
Melissa Officinalis ◽  
Activity Evaluation ◽  
Hsv 1

scholarly journals In vitro activity of the essential oil from Hesperozygis myrtoides on Rhipicephalus (Boophilus) microplus and Haemonchus contortus

2017 ◽  
Vol 27 (1) ◽  
pp. 70-76 ◽  
Author(s):  
Caroline V.V. Castilho ◽  
Rafaela R. Fantatto ◽  
Yousmel A. Gaínza ◽  
Humberto R. Bizzo ◽  
Nancy S. Barbi ◽  
...  
Keyword(s):  
Essential Oil ◽  
Haemonchus Contortus ◽  
Boophilus Microplus ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals In vitro activity evaluation of seven Brazilian Asteraceae against cancer cells and Leishmania amazonensis

2019 ◽  
Vol 121 ◽  
pp. 267-273 ◽  
Author(s):  
Ana Cláudia Nogueira da Silva ◽  
Renato Malveira Carreiro do Nascimento ◽  
Débora Caroline do Nascimento Rodrigues ◽  
Paulo Michel Pinheiro Ferreira ◽  
Cláudia Pessoa ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Leishmania Amazonensis ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Activity Evaluation

scholarly journals Antiprotozoal Activity of Turkish Origanum onites Essential Oil and Its Components

Molecules ◽  
2019 ◽  
Vol 24 (23) ◽  
pp. 4421 ◽  
Author(s):  
Tasdemir ◽  
Kaiser ◽  
Demirci ◽  
Demirci ◽  
Baser
Keyword(s):  
Gas Chromatography ◽  
Essential Oil ◽  
Mammalian Cells ◽  
Leishmania Donovani ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Flame Ionization ◽  
Main Component ◽  
Origanum Onites

Essential oil of Origanum species is well known for antimicrobial activity, but only a few have been evaluated in narrow spectrum antiprotozoal assays. Herein, we assessed the antiprotozoal potential of Turkish Origanum onites L. oil and its major constituents against a panel of parasitic protozoa. The essential oil was obtained by hydrodistillation from the dried herbal parts of O. onites and analyzed by Gas Chromatography-Flame Ionization Detector (GC-FID) and Gas Chromatography coupled with Mass Spectrometry (GC-MS). The in vitro activity of the oil and its major components were evaluated against Trypanosoma brucei rhodesiense, T. cruzi, Leishmania donovani, and Plasmodium falciparum. The main component of the oil was identified as carvacrol (70.6%), followed by linalool (9.7%), p-cymene (7%), γ-terpinene (2.1%), and thymol (1.8%). The oil showed significant in vitro activity against T. b. rhodesiense (IC50 180 ng/mL), and moderate antileishmanial and antiplasmodial effects, without toxicity to mammalian cells. Carvacrol, thymol, and 10 additional abundant oil constituents were tested against the same panel; carvacrol and thymol retained the oil’s in vitro antiparasitic potency. In the T. b. brucei mouse model, thymol, but not carvacrol, extended the mean survival of animals. This study indicates the potential of the essential oil of O. onites and its constituents in the treatment of protozoal infections.

scholarly journals Anti-Legionella Activity of Essential Oil of Satureja cuneifolia

2014 ◽  
Vol 9 (5) ◽  
pp. 1934578X1400900
Author(s):  
Valerija Dunkić ◽  
Antonija Mikrut ◽  
Nada Bezić
Keyword(s):  
Phenolic Compounds ◽  
Essential Oil ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
High Concentration ◽  
Different Sources

The essential oil of Satureja cuneifolia Ten. was characterized by a high concentration of the phenolic compounds carvacrol (21.3%) and thymol (9.2%). The in vitro activity of the essential oil against Legionela pneumophila serogroups (SG) 1 and 2-15 and Legionella spp. from different sources, using micro-dilution, showed that L. pneumofila is sensitive to the oil, with MICs ranging from 0.12 to 0.5%, v/v, and a MBC at 0.5 to 1%, v/v. The essential oil of S. cuneifolia was effective in the reduction of Legionellosis infections.

scholarly journals Antileishmanial in vitro activity of essential oil from Myrciaria plinioides, a native species from Southern Brazil

2019 ◽  
Vol 55 ◽  
Author(s):  
Carla Kauffmann ◽  
Ana Caroline Giacomin ◽  
Kelen Arossi ◽  
Leandra Andressa Pacheco ◽  
Lucélia Hoehne ◽  
...  
Keyword(s):  
Essential Oil ◽  
Native Species ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Southern Brazil

scholarly journals In-vitro Activity of Ferula gummosa Essential Oil and Its Different Extracts on Trichomonas vaginalis

2019 ◽  
Vol 27 (2) ◽  
pp. 1-10
Author(s):  
Mehdi Akbari ◽  
◽  
Dara Dastan ◽  
Mohammad Fallah ◽  
Mohammad Matini ◽  
...  
Keyword(s):  
Essential Oil ◽  
Trichomonas Vaginalis ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals Plants from Northeast Mexico with Anti-HSV Activity

2013 ◽  
Vol 8 (3) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
David Silva-Mares ◽  
Ernesto Torres-López ◽  
Ana M Rivas-Estilla ◽  
Paula Cordero-Pérez ◽  
Noemí Waksman-Minsky ◽  
...  
Keyword(s):  
Methanolic Extract ◽  
Vero Cells ◽  
Vitro Activity ◽  
Active Principle ◽  
In Vitro Activity ◽  
Plaque Reduction Assay ◽  
Methanolic Extracts ◽  
Reduction Assay ◽  
Hsv 1

Based on chemotaxonomic and ethno-pharmacological criteria, three Mexican plants ( Jatropha dioica, Salvia texana and S. ballotaeflora) were studied for in vitro activity against HSV-1 and HSV-2. Hydro-methanolic extracts were initially evaluated for their toxicity to Vero cells. Both Salvia species displayed cytotoxicity at the lowest dose (125 μg/mL). The J. dioica extract showed only negligible cytotoxicity (CC50 644 μg/mL). Its anti-HSV activity was evaluated using the plaque reduction assay with HSV-1 and HSV-2 (from clinical isolates) infected Vero cells. The hydro-methanolic extract of J. dioica showed IC50s of 280 and 370 μg/mL against HSV-1 and HSV-2, respectively. The n-hexane liquid-liquid partition of J. dioica extract contained the majority of the active principle(s) with IC50 values of 300 and 270 μg/mL for HSV-1 and HSV-2, respectively. Bioassay-guided isolation led to the known diterpene, riolozatrione.

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