scholarly journals MICROFILARIA IN PERICARDIAL EFFUSION COEXISTING WITH SPINDLE CELL THYMOMA-A RARE CASE REPORT

2011 ◽  
Vol 01 (04) ◽  
pp. 40-42
Author(s):  
Harish S Permi ◽  
Samaga B N. ◽  
Subramanyam K. ◽  
Jayaprakash Shetty K. ◽  
Teerthanath S. ◽  
...  
Keyword(s):  
Case Report ◽  
Pericardial Effusion ◽  
Mediastinal Mass ◽  
Spindle Cell ◽  
Pericardial Fluid ◽  
Anterior Mediastinal Mass ◽  
Rare Case Report ◽  
Trucut Biopsy ◽  
Cardiac Intensive Care ◽  
Diethyl Carbamazine

AbstractLymphatic filariasis is common in tropical countries and is endemic in South India. Filariasis presenting with pericardial effusion is rare, coexisting with spindle cell thymoma is still very rare. We report a case of a 53-year-old male who was admitted to cardiac intensive care unit with severe breathless since two days. Cardiac Echocardiogram showed massive pericardial effusion with cardiac tamponade and large anterior mediastinal mass. Pericardial fluid aspiration drained 1.5 litres of hemorrhagic fluid. Cytology examination revealed microfilaria of Wutchereria bancrofti. FNAC and trucut biopsy from anterior mediastinal mass showed features of spindle cell thymoma. He was treated with diethyl carbamazine thrice daily for one month. He refused for excision of thymoma. This case report is a rare coexistence of microfilaria in pericardial effusion with spindle cell thymoma. We stress the need to consider filariasis as differential diagnosis in the evaluation of hemorrhagic pericardial effusion especially in endemic areas.

Primary Mucinous Adenocarcinoma of the Thymus: A Case Report and Review of the Literature

2006 ◽  
Vol 130 (2) ◽  
pp. 201-204 ◽  
Author(s):  
Payal Kapur ◽  
Dinesh Rakheja ◽  
Michael Bastasch ◽  
Kyle H. Molberg ◽  
Venetia R. Sarode
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Mucinous Adenocarcinoma ◽  
Mediastinal Mass ◽  
The Body ◽  
Anterior Mediastinal Mass ◽  
Review Of The Literature ◽  
Specific Identification ◽  
Biopsy Specimens ◽  
Thymic Neoplasm

Abstract Primary thymic mucinous adenocarcinoma is extremely rare; to our knowledge, only 2 cases have been reported to date. We describe a third case of primary mucinous adenocarcinoma of the thymus in a 41-year-old man who presented with an anterior mediastinal mass with subsequent metastasis to the lung. The initial diagnosis was of metastatic mucinous adenocarcinoma, but extensive clinical workup of the patient failed to reveal a primary tumor elsewhere in the body. The specific identification of mucinous adenocarcinoma as a primary thymic neoplasm can be difficult or impossible. Morphologic and immunophenotypic similarities to mucinous adenocarcinomas of the gastrointestinal tract can pose diagnostic challenges for surgical pathologists, especially in small biopsy specimens.

Malignant Transformation of Metaplastic Thymoma into High-Grade Sarcomatoid Carcinoma: A Case Report

2021 ◽  
pp. 106689692110704
Author(s):  
Zheng Hua Piao ◽  
Jin Ping Chen ◽  
Hai Ren Chen ◽  
Xin Cheng Zhou
Keyword(s):  
Mediastinal Mass ◽  
Spindle Cell ◽  
Postoperative Radiotherapy ◽  
Sarcomatoid Carcinoma ◽  
Anterior Mediastinal Mass ◽  
High Grade ◽  
Ki 67 ◽  
Cellular Atypia ◽  
Spindle Cells ◽  
Cell Components

The correlation of histogenesis between metaplastic thymoma and thymic sarcomatoid carcinoma is unclear. We report a case of metaplastic thymoma transformed into high-grade sarcomatoid carcinoma. A 64  ×  54  ×  32 mm anterior mediastinal mass in a 61-year-old woman microscopically consisted mainly of classic metaplastic thymoma, with the center dominated by high-grade sarcomatoid carcinoma. In some areas, both epithelial and spindle cell components of the metaplastic thymoma showed increased cellular atypia, mitotic activity, and focal necrosis and gradually transformed into the polygonal/pleomorphic and spindle cell components of sarcomatoid carcinoma. Immunohistochemically, the characteristics of the polygonal/pleomorphic sarcomatoid cells were similar to those of the epithelial component of metaplastic thymoma, while the spindle sarcomatoid cells were more similar to the spindle cells component of metaplastic thymoma. The Ki-67 index was less than 5% in the metaplastic thymoma areas but up to 70% in the sarcomatoid carcinoma area. Radical operation and postoperative radiotherapy were performed. Multifocal relapses at the pleura occurred 13 months after surgery.

An unusual case of thymolipoma as an anterior mediastinal mass in a 17-year-old girl—case report

2016 ◽  
Vol 32 (2) ◽  
pp. 146-148
Author(s):  
Chandan Kumar Ray Mohapatra ◽  
Ranjitsinh Bapusaheb Jadhav ◽  
Abdul Majeed Mulla ◽  
Jayant Vasant Khandekar ◽  
Ganesh Kumar Ammannaya
Keyword(s):  
Case Report ◽  
Unusual Case ◽  
Mediastinal Mass ◽  
Anterior Mediastinal Mass

scholarly journals Caso Clínico: Mesotelioma primario de pericardio

2020 ◽  
Vol 12 (3) ◽  
pp. 222-226
Author(s):  
Juan Sebastián Sánchez León ◽  
Irene Lucía Torres Washima ◽  
Anabel Stefanía Cobos Gálvez ◽  
Gladis Margarita Molina Alvarado
Keyword(s):  
Case Report ◽  
Pericardial Effusion ◽  
Palliative Treatment ◽  
Pericardial Fluid ◽  
Severe Anemia ◽  
Short Term ◽  
Pericardial Mesothelioma ◽  
The World ◽  
Oncological Diseases ◽  
Low Incidence

BACKGROUND: Primary pericardial mesothelioma is an extremely rare mesodermal tumor, among oncological diseases, with a very low incidence. About 350 cases have been described around the world, most of them diagnosed post-mortem. The short term prognosis is poor, regardless of the treatment, which is mostly palliative. We present a case report regarding this pathology. CASE REPORT: 69 year old patient hospitalized with dyspnea and severe anemia. Complementary workup showed pleural effusion and pericardial effusion. Histopathology report of the pericardial fluid revealed pericardial mesothelioma. EVOLUTION: Due to recurrence of pericardial effusion, it was decided to perform pericardiectomy and left pleurectomy as palliative treatment, to alleviate the patient’s symptoms. Chemotherapy was planned after the procedure, but the patient’s general condition deteriorated severely leading to his death. CONCLUSION: Primary pericardial mesothelioma is a rare tumor, whose symptoms are characterized by the associated pericardial effusion, making the diagnosis difficult due to it low incidence. The prognosis is poor in short- term, and there isn’t an established protocol for the treatment with results that showed improve in mortality. KEYWORDS: MESOTHELIOMA, PERICARDIAL EFFUSION, PERICARDIECTOMY, PLEUROTOMY.

scholarly journals Pulmonary Spindle Cell Carcinoma: A Rare Case Report

Cureus ◽  
2019 ◽  
Author(s):  
Salman Khan ◽  
Binita Dahal ◽  
Faraz Siddiqui ◽  
Kim J Norville ◽  
Apurwa Karki
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Rare Case ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Rare Case Report
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