Continuous-Flow Nickel/Photocatalytic C–N Cross-Coupling of Aryl Halides and Hydrazine Nucleophiles

Synfacts ◽  
2021 ◽  
Vol 17 (02) ◽  
pp. 0233
2019 ◽  
Author(s):  
Randolph Escobar ◽  
Jeffrey Johannes

<div>While carbon-heteroatom cross coupling reactions have been extensively studied, many methods are specific and</div><div>limited to a set of substrates or functional groups. Reported here is a method that allows for C-O, C-N and C-S cross coupling reactions under one general methodology. We propose that an energy transfer pathway, in which an iridium photosensitizer produces an excited nickel (II) complex, is responsible for the key reductive elimination step that couples aryl halides to 1° and 2° alcohols, anilines, thiophenols, carbamates and sulfonamides.</div>


Author(s):  
Qing He ◽  
Wenli Wang ◽  
Yong Liang ◽  
Zunting Zhang ◽  
Stanislaw F. Wnuk

ChemInform ◽  
2016 ◽  
Vol 47 (12) ◽  
pp. no-no
Author(s):  
Anns Maria Thomas ◽  
Sujatha Asha ◽  
K. S.. Sindhu ◽  
Gopinathan Anilkumar

ChemCatChem ◽  
2010 ◽  
Vol 3 (1) ◽  
pp. 146-149 ◽  
Author(s):  
Rongzhao Zhang ◽  
Jianming Liu ◽  
Shoufeng Wang ◽  
Jianzhong Niu ◽  
Chungu Xia ◽  
...  

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