Bone Abnormalities in Mice with Protein Kinase A (PKA) Defects Reveal a Role of Cyclic AMP Signaling in Bone Stromal Cell-Dependent Tumor Development

2016 ◽  
Vol 48 (11) ◽  
pp. 714-725 ◽  
Author(s):  
S. Liu ◽  
J. Shapiro ◽  
E. Saloustros ◽  
C. Stratakis
Keyword(s):  
Protein Kinase ◽  
Cyclic Amp ◽  
Protein Kinase A ◽  
Stromal Cell ◽  
Tumor Development ◽  
Bone Abnormalities ◽  
Kinase A ◽  
Cyclic Amp Signaling

scholarly journals Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors

2010 ◽  
Vol 20 (1) ◽  
pp. 165-175 ◽  
Author(s):  
Madson Q. Almeida ◽  
Kit Man Tsang ◽  
Chris Cheadle ◽  
Tonya Watkins ◽  
Jean-Charles Grivel ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Cyclic Amp ◽  
Protein Kinase A ◽  
Stromal Cell ◽  
Inflammatory Pathways ◽  
Caspase 1 ◽  
Kinase A ◽  
Osteoblast Progenitors

The Role of Cyclic AMP and Its Effect on Protein Kinase A in the Mitogenic Action of Thyrotropin on the Thyroid Cell

2002 ◽  
Vol 968 (1) ◽  
pp. 106-121 ◽  
Author(s):  
S. DREMIER ◽  
K. COULONVAL ◽  
S. PERPETE ◽  
F. VANDEPUT ◽  
N. FORTEMAISON ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Cyclic Amp ◽  
Protein Kinase A ◽  
Thyroid Cell ◽  
Mitogenic Action ◽  
Kinase A

Retinal neuromodulation: The role of dopamine

1991 ◽  
Vol 7 (1-2) ◽  
pp. 87-97 ◽  
Author(s):  
John E. Dowling
Keyword(s):  
Protein Kinase ◽  
Cyclic Amp ◽  
Protein Kinase A ◽  
Phorbol Esters ◽  
Electrical Coupling ◽  
Horizontal Cells ◽  
Neurite Retraction ◽  
Gap Junctional ◽  
Kinase A

AbstractDopamine exerts multiple effects on retinal horizontal cells. Dopamine, via cyclic AMP and protein kinase A, reduces the light responsiveness of horizontal cells and the electrical coupling between the cells. The gating kinetics of both gap-junctional and glutamate channels are altered as a result of phosphorylation by protein kinase A. Dopamine also causes a reversible retraction of neurites of horizontal cells maintained in culture. Diacylglycerol analogues as well as phorbol esters mimic this effect of dopamine, but not cyclic AMP analogues or Forskolin. The results suggest that dopamine causes neurite retraction by the activation of protein kinase C via diacylglycerol.

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