Cyclic Amp-Mediated Aquaporin-2 Translocation: Identification of Protein Kinase a Anchoring Proteins and the Role of the Small GTPases of the Rho Family

2000 ◽  
pp. 145-149
Author(s):  
Enno Klussmann ◽  
Eberhard Krause ◽  
Burkhard Wiesner ◽  
Michael Beyermann ◽  
Bayram Edemir ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Cyclic Amp ◽  
Protein Kinase A ◽  
Small Gtpases ◽  
Aquaporin 2 ◽  
Anchoring Proteins ◽  
Rho Family ◽  
Kinase A

A-kinase-anchoring proteins and cytoskeletal signalling events

2003 ◽  
Vol 31 (1) ◽  
pp. 87-89 ◽  
Author(s):  
J.D. Scott
Keyword(s):  
Protein Kinase ◽  
Molecular Mass ◽  
Protein Kinase A ◽  
Protein Kinases ◽  
Recent Progress ◽  
Membrane Receptors ◽  
Anchoring Proteins ◽  
Syndrome Protein ◽  
Kinase A

Targeting of protein kinases and phosphatases to the cytoskeleton enhances the regulation of many signalling events. Cytoskeletal signalling complexes facilitate this process by optimizing the relay of messages from membrane receptors to specific sites on the actin cytoskeleton. These signals influence fundamental cell properties such as shape, movement and division. Targeting of the cAMP-dependent kinase (protein kinase A) and other enzymes to this compartment is achieved through interaction with A-kinase-anchoring proteins (AKAPs). The present paper discusses recent progress on dissecting the biological role of WAVE1 (Wiskott–Alrich syndrome protein family verprolin homology protein 1), an AKAP that assembles a cytoskeletal transduction complex in response to signals that emanate from the low-molecular-mass GTPase, Rac.

The Role of Cyclic AMP and Its Effect on Protein Kinase A in the Mitogenic Action of Thyrotropin on the Thyroid Cell

2002 ◽  
Vol 968 (1) ◽  
pp. 106-121 ◽  
Author(s):  
S. DREMIER ◽  
K. COULONVAL ◽  
S. PERPETE ◽  
F. VANDEPUT ◽  
N. FORTEMAISON ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Cyclic Amp ◽  
Protein Kinase A ◽  
Thyroid Cell ◽  
Mitogenic Action ◽  
Kinase A

scholarly journals Protein Kinase A Anchoring Proteins Are Required for Vasopressin-mediated Translocation of Aquaporin-2 into Cell Membranes of Renal Principal Cells

1999 ◽  
Vol 274 (8) ◽  
pp. 4934-4938 ◽  
Author(s):  
Enno Klussmann ◽  
Kenan Maric ◽  
Burkhard Wiesner ◽  
Michael Beyermann ◽  
Walter Rosenthal
Keyword(s):  
Protein Kinase ◽  
Protein Kinase A ◽  
Cell Membranes ◽  
Principal Cells ◽  
Aquaporin 2 ◽  
Anchoring Proteins ◽  
Kinase A
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