A Critical Review on BIM Research Process and Future Trends at Home and Abroad

ICCREM 2018 ◽  
2018 ◽  
Author(s):  
Jiaqing Chen ◽  
Qingpeng Man
Author(s):  
Shuo Wang ◽  
Chuanbin Mao ◽  
Shanrong Liu

AbstractIn recent years, noncoding gene (NCG) translation events have been frequently discovered. The resultant peptides, as novel findings in the life sciences, perform unexpected functions of increasingly recognized importance in many fundamental biological and pathological processes. The emergence of these novel peptides, in turn, has advanced the field of genomics while indispensably aiding living organisms. The peptides from NCGs serve as important links between extracellular stimuli and intracellular adjustment mechanisms. These peptides are also important entry points for further exploration of the mysteries of life that may trigger a new round of revolutionary biotechnological discoveries. Insights into NCG-derived peptides will assist in understanding the secrets of life and the causes of diseases, and will also open up new paths to the treatment of diseases such as cancer. Here, a critical review is presented on the action modes and biological functions of the peptides encoded by NCGs. The challenges and future trends in searching for and studying NCG peptides are also critically discussed.


Author(s):  
Michelle Lee D'Abundo ◽  
Saliha Akhtar ◽  
Cynthia Israel

Increasing the participation of women and minorities in clinical trials is a challenge for the healthcare industry. The lack of diversity in clinical trials prevents the tailoring of healthcare interventions specifically for women and minorities. The purpose of this paper is to explore how technology-oriented strategies can be applied in the clinical trial research process to increase the recruitment of women and minorities in clinical trials. An overview of clinical trials, the stakeholders, and current issues in diversifying recruitment are provided. In order to recruit diverse participant populations, the use of online advertising, social media, e-newsletters, tablets, smartphones, and apps are detailed. Lessons from previous use of technology in recruitment are outlined as well as future trends. With the support of clinical trial stakeholders, the current technology-oriented strategies available seem promising as methods for increasing the participation of women and minorities in clinical trials.


2019 ◽  
Vol 15 (1) ◽  
pp. 68-86 ◽  
Author(s):  
Christian William Callaghan

Purpose This paper aims to argue that certain insights offered by Kuhn and Foucault may be of use to those seeking to resist a global paradigm of inequality in access to the outcomes of pharmaceutical development. It is further argued that these relationships are not independent of certain power relationships. This critical review seeks to highlight certain of these power relationships, and to suggest how they might be better managed to ensure more equitable outcomes for those in society that are most vulnerable to innovation failure. Design/methodology/approach This research takes the form of a critical review paper, seeking to develop theory though a synthesis of literature. Findings Unlike market incentives, it might be the research process itself that is most vulnerable to stakeholder resistance to slow and unequal delivery of life-saving pharmaceutical development. Given that a lack of responsiveness to societal needs can itself be considered unethical, Kuhnian theory predicting pharmaceutical innovation failure is related to what Foucault describes as a system of oppression, whereby power relationships disadvantage those most vulnerable and powerless. Research limitations/implications Given the rise of movements like citizen science and participant-led research, as well as new ethical frameworks premised on increasing accountability in science, Foucault’s principles are considered to echo a general trend towards the democratisation of science, and towards increasing the responsiveness of pharmaceutical development to societal needs. Originality/value A novel synthesis of literature is undertaken, offering useful theoretical insights into how social actors might contribute to enabling a more responsive system of international healthcare business.


2014 ◽  
Vol 21 (5) ◽  
pp. 507-517 ◽  
Author(s):  
Arne Rehnsfeldt ◽  
Lillemor Lindwall ◽  
Vibeke Lohne ◽  
Britt Lillestø ◽  
Åshild Slettebø ◽  
...  

Background: As part of an ongoing Scandinavian project on the dignity of care for older people, this study is based on ‘clinical caring science’ as a scientific discipline. Clinical caring science examines how ground concepts, axioms and theories are expressed in different clinical contexts. Central notions are caring culture, dignity, at-home-ness, the little extra, non-caring cultures versus caring cultures and ethical context – and climate. Aim and assumptions: This study investigates the individual variations of caring cultures in relation to dignity and how it is expressed in caring acts and ethical contexts. Three assumptions are formulated: (1) the caring culture of nursing homes influences whether dignified care is provided, (2) an ethos that is reflected on and appropriated by the caregiver mirrors itself in ethical caring acts and as artful caring in an ethical context and (3) caring culture is assumed to be a more ontological or universal concept than, for example, an ethical context or ethical person-to-person acts. Research design: The methodological approach is hermeneutic. The data consist of 28 interviews with relatives of older persons from Norway, Denmark and Sweden. Ethical considerations: The principles of voluntariness, confidentiality and anonymity were respected during the whole research process. Findings: Three patterns were revealed: dignity as at-home-ness, dignity as the little extra and non-dignifying ethical context. Discussion: Caring communion, invitation, at-home-ness and ‘the little extra’ are expressions of ethical contexts and caring acts in a caring culture. A non-caring culture may not consider the dignity of its residents and may be represented by routinized care that values organizational efficiency and instrumentalism rather than an individual’s dignity and self-worth. Conclusion: An ethos must be integrated in both the organization and in the individual caregiver in order to be expressed in caring acts and in an ethical context that supports these caring acts.


Author(s):  
Kshama Kawale

Now a days, people are comparatively much more conscious about their skin care as it’s a compulsory part of their personality building for this purpose people are using a number of products prepared chemically, which ultimately harms their skin cosmeceuticals are one of such product So, it is better to follow the herbal care for the skin, most herbal skin care product don’t have any side effects. Moreover herbal skin care drugs can be easily made at home, hence making them even more attractive, so herbal skin care is the way to go4. Hence, study of Ayurvedic drugs and the preventive aspects which describe skin care in Ayurvedic compendia is necessiated, which will help in curing various skin problems1 .


2021 ◽  
Vol 163 ◽  
pp. 106430
Author(s):  
Gabriel F. Serra ◽  
Fábio A.O. Fernandes ◽  
Eduardo Noronha ◽  
Ricardo J. Alves de Sousa

2017 ◽  
pp. 1018-1028
Author(s):  
Michelle Lee D'Abundo ◽  
Saliha Akhtar ◽  
Cynthia Israel

Increasing the participation of women and minorities in clinical trials is a challenge for the healthcare industry. The lack of diversity in clinical trials prevents the tailoring of healthcare interventions specifically for women and minorities. The purpose of this paper is to explore how technology-oriented strategies can be applied in the clinical trial research process to increase the recruitment of women and minorities in clinical trials. An overview of clinical trials, the stakeholders, and current issues in diversifying recruitment are provided. In order to recruit diverse participant populations, the use of online advertising, social media, e-newsletters, tablets, smartphones, and apps are detailed. Lessons from previous use of technology in recruitment are outlined as well as future trends. With the support of clinical trial stakeholders, the current technology-oriented strategies available seem promising as methods for increasing the participation of women and minorities in clinical trials.


1991 ◽  
Vol 2 (3) ◽  
pp. 477-487
Author(s):  
Peter M. Rutan

The ventricular assist device (VAD) is one of the latest tools available to help the clinician contend with severe heart failure. This article presents a historical overview of the development of the VAD and discusses the incidence and etiology of heart failure. The investigational device research process, nursing involvement, and future trends are discussed


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