A A Pharmacological Study of Anupa and Jangala Deshastha Shitivaraka (Celosia argentea Linn.). W.S.R. Mootralkarma

Pharmacology, the science of drug action, has helped to elucidate many basic physiological and pathological mechanisms in health and disease. Various animal experimental models have been designed to study the effect of drugs on living organisms and isolated tissues. These give an insight about where and how a drug acts, the mode of action of a drug, its effect on various body systems and probable adverse effects before administration of a drug. Therefore, the object of pharmacology is to provide such scientific data in animals as well as humans, which forms the basis of rational therapeutics. The Jalamahabhuta is fundamental base of origin for kapha dosha and mootra. These are supposed to have Asray-Asrayi Sambandha . It means these are directly proportional to each other. So by using the drug which is having the mootrala property Kapha may be controlled. Here an effort is made to prove this concept with modern parameters like immunomodulation, anti-inflammatory and antihistaminic activity.

The The role of Sarvang sundar rasa Orally and Mahamash tail locally in the management of Amavata WSR to Rheumatoid Arthritis –A case study.

Amavata is term derives from the word as Ama and vata.Ama is a type of metabolic toxin; it is an essential factor in development of pathology.Mandagni (low digestive fire) produce Ama in the body,when ama get associated with vitiated vata and starts circulating in the body accupies in shleshmal sthana(asthi sandhi) results in painful disease Amavata. Madhavakara (900 AD) has identified first time the disease.Amavata as seprate entity and discribed the disease in detail.Madhavakara describes etiopathology of amavata that the person with weak digestion (Mandagni) if he is posseses a secondary life (nishchalasya)or if he indulges into virrudha aaharaand vihara e.g.excessive exercise after taking heavy and fatty food,ama is produced and vata get vitiated. This ama provoks by vata (Vayuna preritah),Circulates in the body especially towards shleshmal sthanas. the resultant of cardinal symptoms of amvata are painful swelling of the joints (sarujashotham ) of hands,feet,ankle,knee,hip,Spinal column,and stiffness(jadyata),fever( Jwara),loss of appetite (aruchi),indigestion (apaka),Constipation(vibandhata),gurguling(antrakujanam)etc. this impairs the day to day functions of person.in spite of presence of NSAID,DMRD,steroids etc. the rheumatology remains refractory to treatment but Ayurvedic drug which are therapeutically safe and effectiveness.

Comparative Pharmaceutical -Analytical study of Sushruta Lauha Ayaskriti and Lauha Bhasma

Ayaskriti is an ayurvedic formulation containing iron. It is a specific metal processing technique developed in ancient times to make iron suitable for internal use. Objective: To prepare and physicochemically evaluate lauha Ayaskriti (shusruta) and lauha bhasma. Materials and methods: lauha Ayaskriti (shusruta) and lauha bhasma was prepared as per ayurvedic text and characterized by Organoleptic characters, physico-chemical parameters. Results: This study clearly revealed bhasma prepared as per Sushruta and Rastangini are passed as per ayurvedic bhasma pariksha. Conclusion: The study of XRF of lauha Ayaskriti and lauha bhasma value of fe is persent in the elemental form along with other form of oxide. Further studies are required to prove the medicinal efficacy of this medicine.

EXPLORING THE POSSIBILITIES AND CHALLENGES IN IMMUNOMODULATORY STRATEGIES IN KAUMARABHRITYA WITH SPECIAL REFERENCE TO YUKTIKRITA BALA

Immunization has been one of the biggest success stories of modern medicine. The WHO estimates that at least 10 million deaths were prevented between 2010 and 2015.Ayurveda upholds the unique principles of strengthening innate resistance of an individual in prevention and cure of diseases which is inculcated from the time of conception.The bala or vyadhikshamatva is the functional aspect of ojus.Vyadhi utpadak pratibandhakatva and Vyadhibala virodhitva which are the two aspects of vyadhikshamatva are determined and controlled by the state of Ojus.The immunomodulation is done through the medium of medicines at proper age, dose and state of body along with proper diet,regimen and state of mind. The study explores the immuno modulation strategies in children through a literature survey through the Brhat trayee and kaumarabhritya classics like Kashyapa samhitha,Arogya kalpadruma along with relevant online articles..”Prakara yoga” will be elaborated for its immunomodulatory action.An experience survey among ayurveda experts for the use of methodologies for use and practicality of these strategies also is included. Key words : immunomodulation,vyadhikshamatva,ayurveda.

'Critical Study Of Konkan Territory Of Maharashtra State w.s.r. To The Concept Of Desha ln Ayurveda'

Background- Desha Pariksha (examination) has been mentioned in the Charaka Samhita (cha.vi.8/84) which is considered as the oldest and the most authentic treatise of Ayurveda. Ayurveda has described three types of Desha viz. Jangl , Anup and Sadharan. Desha also known as Bhumi refers to the natural inhabitant of an individual. Desha is one of the factors which have to be assessed in ascertaining the Hetu (etiological factors) and also in deciding the treatment. Climate, diseases, food, treatment and so many factors may vary according to desh (habitat). An attempt has been made to critically analyse the konkan region of the state Maharashtra considering present climate conditions and geography in comparison to the concept of Ayurvedic desha description. Methods- Authentic government web portals of this region have been visited to know the present climatic situations. Various research papers were also reviewed to discern the territory from other parts of the state. Conclusion- After scrutinizing the facts over the past few years; it has been found that most of the regions of konkan fall under excess rainfall terrain. Flora and fauna is similar to that of wetland. The Konkan region of the Maharashtra State can be compared with Anup desha in Ayurveda.

A literary study of purvarupa (prodromal features ) w. s. r. to prameha vyadhi purvarupa.

In Ayurvedic science, diagnosis of the disease is done with help of Nidan Panchakaaa. In five-fold examination, Purvarupa is one of the component parts of Nidan Panchaka. Purvarupa means Prodromal features of diseases. Any disease does not appear suddenly. Time taken between etiological factors intake to the appearance of specific disease is of Purvarupa. They are premonitory features that manifest before the actual emergence of disease. These symptoms could be doshik or adoshik. Purvarupa are of two types, general and specific. Careful understanding of Purvarupa helps in the differential diagnosis of diseases. Purvarupa also helps to determine the prognosis of any disease. The appearance of all Purvarupa of any disease is considered a bad prognosis because it means the disease is incurable. At Purvarupa stage, treatment modalities for any disease are simpler or easier. So the knowledge of Purvarupa is essential. In samhitas the Purvarupa (Prodromal features )of Prameha vyadhi is described very well. As the Prameha vyadhi is asadhya in its chronic stage as well as it may cause many serious complications if it is not treated and controlled in the early stage, it is very important to know the disease in very primary stage.This is possible by detecting the prameha Purvarupas in patient earlier. So that we can diagnose this stage and can prevent developing it further in vyaktavastha. So in this review study, an attempt is made to elaborate on the importance of Purvarupas and to compile the Purvarupas of Prameha from all ayurvedic samhitas.

A CRITICAL REVIEW OF TWAK ACCORDING TO AYURVEDIC COMPENDIA W.S.R. TO PREVENTIVE ASPECTS OF SKIN DISEASE

Now a days, people are comparatively much more conscious about their skin care as it’s a compulsory part of their personality building for this purpose people are using a number of products prepared chemically, which ultimately harms their skin cosmeceuticals are one of such product So, it is better to follow the herbal care for the skin, most herbal skin care product don’t have any side effects. Moreover herbal skin care drugs can be easily made at home, hence making them even more attractive, so herbal skin care is the way to go4. Hence, study of Ayurvedic drugs and the preventive aspects which describe skin care in Ayurvedic compendia is necessiated, which will help in curing various skin problems1 .

REVIEW OF VRANASHOPHA W.S.R. TO INFLAMMATORY SWELLINGS

Acharya Sushruta had a complete knowledge of Vranashopha and described Vranashopha into 3 progressive stages. Inflammation in Ayurveda is known by different names in different contexts namely Shotha, Shopha, Svayatu and Utsedha. Inflammation is duly recognised in Ayurveda as a pathological manifestation, while Modern Medicine considers Inflammation as a symptom or rather as a healing response of the body. Ayurveda treats the concepts of Inflammation as symptom of a disease, an independent disease and complication of disease. Vranashopha shares common pathological features of Inflammation. The disturbances in micro channel circulation in Inflammation are due to Srotodusti (clogging of channels) by Amma (toxic waste of metabolism). The proper clinical approch to Vranashopha with Modern concept plays a important role in management and preventing complication of Vranashopha.

Review on –Agrya Ayushadi Dravyas acting on different body systems w. s. r. to charaka samhita.

Ayurveda is an ancient medical science which main aim is to maintain the health of a healthy person and cure diseases from its root. Ayurved is based on Saptapadartha, where dravya is one of them. Ancient Acharyas classified the Ayurveda into eight branches, collectively known as “Ashtang Ayurveda”. Dravyaguna Shastra is an important branch of chikitsa shastra. This deals with the guna (properties), karma (action), and Prayoganum (therapeutic uses of dravya). In Ayurveda “Ekal dravya” chikitsa having more importance. In some context, a single drug (Ekal Dravya) is used for one disease or more than one disease. Agrya Aushadhi Dravya is the most potent drug for that particular disease. Agrya Aushadhi Dravya is cost-effective economical, easy to use, and safe. This article highlighting the Agrya Aushadhi dravya mentioned in a charak samhita which acting on different body systems.