Blood flow in abdominal aortic aneurysms indicates severity and threat

Scilight ◽  
2021 ◽  
Vol 2021 (47) ◽  
pp. 471107
Author(s):  
Anne Cockshott
Keyword(s):  
Blood Flow ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Abdominal Aortic

scholarly journals Cardiac complications and their prevention in surgery of infrarenal abdominal aortic aneurysms

2015 ◽  
Vol 17 (1) ◽  
pp. 79
Author(s):  
A. A. Karpenko ◽  
A. M. Chernyavskiy ◽  
N. R. Rakhmetov ◽  
A. A. Dyusupov ◽  
Ye. O. Masalimov ◽  
...  
Keyword(s):  
Blood Flow ◽  
Surgical Treatment ◽  
Endovascular Repair ◽  
Open Surgery ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Surgical Correction ◽  
Cardiac Complications ◽  
Abdominal Aortic

We analyzed the data of surgical treatment of 225 patients with infrarenal abdominal aortic aneurysms (AAA) obtained over a period from 1998 to 2012. Depending on the tactics and methods of surgical treatment, the patients were divided into 3 groups. Group 1 included 79 patients (35,2%), who underwent open surgery for AAA with therapeutic correction of combined pathology in the blood pool of the heart. Group 2 had 118 patients (52,4%), who underwent first surgical correction of the arterial bed of the heart and then open surgery for AAA. 28 patients of Group 3 (12,4 %) also underwent first surgical correction in the arterial bed area followed, however, by endovascular repair of AAA. Preliminary surgical correction of the coronary blood flow abnormalities followed by open surgery of AAA allowed to reduce the number of myocardial infarctions in the early postoperative period from 10,1 % to 1,7% and from 12,5% to 1,3% in the long-term period, to reliably reduce perioperative mortality from 10,1% to 0,8% and to improve the actuarial 5-year survival from 77,5% to 91,3%. The absence of cardiac complications after preliminary surgical correction of the coronary blood flow and endovascular repair of AAA both during early and long-term follow-up is indicative of the benefits of this tactic, especially for the elderly with multiple co-morbidities.

A COMPUTATIONAL MODEL OF BLOOD FLOW AND AORTIC WALL STRESS IN ABDOMINAL AORTIC ANEURYSMS

ASAIO Journal ◽  
1999 ◽  
Vol 45 (2) ◽  
pp. 197
Author(s):  
P J Cabrales ◽  
J E Gómez ◽  
J Camacho ◽  
C Espinel ◽  
J C Briceño
Keyword(s):  
Blood Flow ◽  
Computational Model ◽  
Aortic Wall ◽  
Wall Stress ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Abdominal Aortic

Adenosine-Induced Transient Cardiac Asystole Enhances Precise Deployment of Stent-Grafts in the Thoracic or Abdominal Aorta

1996 ◽  
Vol 3 (3) ◽  
pp. 270-272 ◽  
Author(s):  
Gerald Dorros ◽  
Joel M. Conn
Keyword(s):  
Blood Flow ◽  
Aortic Aneurysm ◽  
Abdominal Aorta ◽  
Endovascular Repair ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Aortic Flow ◽  
Stent Grafts ◽  
Abdominal Aortic ◽  
Second Period

Purpose: To present a cardiac asystole technique that assists in the accurate deployment of stent-grafts during endovascular repair of thoracic or abdominal aortic aneurysms. Technique: In the anesthetized patient, trial doses of intravenous adenosine are delivered until a ≥ 20-second period of asystole is recorded. The endograft procedure then proceeds until the device is ready for deployment. The predetermined dose of adenosine is administered, and the device is deployed during asystole. Adenosine-induced transient asystole has been utilized in 16 patients undergoing balloon-expandable endograft exclusion of 6 thoracic aortic and 10 abdominal aortic aneurysms. Asystole lasted for 20 to 30 seconds, during which time the devices were accurately deployed without interference from the aortic flow. There were no clinical sequelae of this technique in any patient. Conclusions: Pharmacologically induced transient asystole appears to be a safe maneuver to preclude endograft movement by systolic blood flow. The technique permits precise placement of balloon-expandable stent-grafts and is applicable to self-expanding devices as well. Interventionists may wish to incorporate adenosine-induced asystole into their aortic aneurysm exclusion procedures.

Effect of macroscale formation of intraluminal thrombus on blood flow in abdominal aortic aneurysms

2015 ◽  
Vol 19 (1) ◽  
pp. 84-92 ◽  
Author(s):  
Anastasios Raptis ◽  
Michalis Xenos ◽  
Stelios Dimas ◽  
Athanasios Giannoukas ◽  
Nicos Labropoulos ◽  
...  
Keyword(s):  
Blood Flow ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Intraluminal Thrombus ◽  
Abdominal Aortic

Abstract 306: Murine Abdominal Aortic Aneurysms Demonstrate Heterogeneous Growth and Remodelling by High-frequency Ultrasound

2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Evan H Phillips ◽  
Paolo Di Achille ◽  
Matthew R Bersi ◽  
Jay D Humphrey ◽  
Craig J Goergen
Keyword(s):  
Blood Flow ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
High Frequency ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
High Frequency Ultrasound ◽  
True Lumen ◽  
Abdominal Aortic ◽  
Frequency Ultrasound

In vivo imaging of vascular disease models has been largely underutilized, but it can greatly benefit cardiovascular research. An improved understanding of the development of the angiotensin II (AngII) apolipoprotein E knockout model of abdominal aortic aneurysms (AAAs) could help patients with this life-threatening disease. The objective of this study was to investigate the early hemodynamic, biomechanical, and volumetric changes in AngII AAAs using high-frequency ultrasound. Five male apolipoprotein E-deficient C57BL/6J mice were subcutaneously implanted with AngII-loaded miniosmotic pumps (1000 ng/kg/min) and screened for appearance of AAAs. We acquired imaging data of the morphology, pulsatility, and blood flow profiles in newly formed AAAs over 7 days. We found that biomechanical and hemodynamic changes occurred during initial AAA formation alongside an increase in AAA volume. Average AAA volume increased by 140±24% between baseline and AAA diagnosis, while true lumen volume decreased by 46±12% due to formation of a focal dissection. The resulting intramural thrombus evolved in shape and volume but with variability between animals. Regional differences in blood flow velocity were apparent down the length of the largest AAAs and mean blood flow velocity significantly increased by 150±42% upon initial aortic expansion and true lumen narrowing. Mean velocity decreased over 7 days as the total AAA volume increased. Circumferential cyclic strain also significantly decreased upon initial aortic expansion and remained reduced, indicating the AAAs had stiffened vessel walls with initial aortic expansion. We are also exploring the heterogeneity of this AAA development using computational pulsatile flow models built from these ultrasound datasets. These models can provide information on site-specific changes in wall shear stress and oscillatory shear index, which are potentially predictive metrics for intramural thrombus formation and AAA growth.

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