Assessment of antioxidant activity of an intracanal medicament containing grape seed extract

AbstractElectrospinning is a common technique used for the production of nanofibers, and it is based on the fact that the electrically charged liquid polymer is positioned in a continuous fiber form on a grounded surface. Grape seed is rich in phenolic compounds and can be used as a dietary supplement or as a natural antioxidant source in diet. In this study, grape seed extract of Burdur Dimrit variety (Vitis vinifera L.) was electrospun with gelatin, polyvinyl alcohol (PVA) and PVA/β-cyclodextrin polymers to produce nanofibers with antioxidant activity. The aim of this study was to determine the effect of the electrospinning process on the total antioxidant activity and total phenolic contents of electrospun polymers with grape seed extracts. Total antioxidant activity of samples (by ABTS and DPPH assays) and total phenolic contents (Folin–Ciocalteu method) were determined before and after the electrospinning process of polymers with grape seed extract. Electrospinning with gelatin polymer decreased the antioxidant activity (ABTS assay) of nanofibers containing grape seed extract by 65% and their total phenolic contents by 7%. However, electrospinning treatment with PVA and PVA/β-cyclodextrin had no effect on the total antioxidant activity (ABTS and DPPH) and total phenolic substance contents of grape seed extract nanofibers.

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Effect of grape seed extract on growth performance, protein and polyphenol digestibilities, and antioxidant activity in chickens

Spanish Journal of Agricultural Research ◽

10.5424/sjar/2010082-1199 ◽

2010 ◽

Vol 8 (2) ◽

pp. 326 ◽

Cited By ~ 47

Author(s):

A. Brenes ◽

A. Viveros ◽

I. Goñi ◽

C. Centeno ◽

F. Saura-Calixto ◽

...

Keyword(s):

Antioxidant Activity ◽

Growth Performance ◽

Grape Seed Extract ◽

Grape Seed ◽

Seed Extract

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Grape Seeds Extract as Brain Food: A Review

International Journal of Pharmaceutical and Clinical Research ◽

10.25258/ijpcr.v9i1.8270 ◽

2017 ◽

Vol 9 (1) ◽

Author(s):

Souad El Gengaihi ◽

Doha H. Abou Baker

Keyword(s):

Antioxidant Activities ◽

Complex Mixture ◽

Grape Seed Extract ◽

Grape Seed ◽

Seed Extract ◽

Amyloid Peptide ◽

Grape Seeds ◽

Potential Benefits ◽

Reduced Risk

Interest in the biological role of bioactive compounds present in medicinal herbs has increased over the last years. Of particular interest are plants that have an anti-Alzheimer activities. Several plants can be useful for Alzheimer (AD) management. Such as these which have anti-inflammatory activity, acetylcholinesterase (AChE) inhibitory action, antiapoptotic, slow the aggregation of amyloid peptide and antioxidant activities. Grape seed extract (GSE) is a complex mixture of several compounds, mostly represented by polyphenols and flavonoids. Their consumption is safe and is recognized to exert several health benefits. GS flavonoids have been associated with the reduced risk of chronic diseases, we present some findings on the potential benefits of GSE for the treatment of AD.

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