Environmentally benign synthesis of benzoic acid coupled benzimidazole by using PEG-600

2021 ◽  
Author(s):  
Srinivasa Reddy Bireddy ◽  
Venkata Ramana Reddy Chittireddy ◽  
Laxminarayana Eppakayala
Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3667
Author(s):  
Mashooq A. Bhat ◽  
Ahmed M. Naglah ◽  
Siddique Akber Ansari ◽  
Hanaa M. Al-Tuwajiria ◽  
Abdullah Al-Dhfyan

A ChCl: Gly (DESs) promoted environmentally benign method was developed for the first time using the reaction of aryl aldehydes and dimedone to give excellent yields of xanthene analogues. The major application of this present protocol is the use of green solvent, a wide range of substrate, short reaction times, ease of recovery, the recyclability of the catalyst, high reaction yield, and ChCl: Gly as an alternative catalyst and solvent. In addition to this, all the synthesized compounds were evaluated for their in vitro antimycobacterial activity against M. tuberculosis H37Ra (MTB) and M. bovis BCG strains. The compounds 3d, 3e, 3f, and 3j showed significant antitubercular activity against MTB and M. bovis strains with minimum inhibitory concentration (MIC) values of 2.5−15.10 µg/mL and 0.26–14.92 µg/mL, respectively. The compounds 3e, 3f, and 3j were found to be nontoxic against MCF-7, A549, HCT 116, and THP-1 cell lines. All the prepared compounds were confirmed by 1H NMR and 13C NMR analysis.


2018 ◽  
Vol 10 (1) ◽  
pp. 39-50
Author(s):  
M. Rana ◽  
A. Rahman ◽  
P. K. Roy ◽  
H. N. Roy

(S)-3-Methyl-1, 1-diphenylbutane-1, 2-diamine has been found to be a mild and effective organocatalyst for one-pot 4-components synthesis of 1, 2, 4, 5-tetra-substituted imidazoles. The key benefits of this protocol is high yielding, cost effectiveness, easy purification and above all, environmentally benign.


2017 ◽  
Vol 16 (12) ◽  
pp. 1792-1800 ◽  
Author(s):  
Minki Baek ◽  
Eun-Ju Kim ◽  
Seok Won Hong ◽  
Wooyul Kim ◽  
Kijung Yong

CuInS2(CIS)/ZnO is a superb photocatalyst for organic dye and bacteria decomposition. In this paper, photocatalytic mechanism of the heterostructure is investigated through controlled experiments under various scavenging conditions.


2013 ◽  
Vol 13 (3) ◽  
pp. 2189-2192 ◽  
Author(s):  
Chalermchai Pilapong ◽  
Somchai Thongtem ◽  
Titipun Thongtem

2018 ◽  
Vol 21 (9) ◽  
pp. 814-821 ◽  
Author(s):  
Supriya S. Khot ◽  
Prashant V. Anbhule ◽  
Uday V. Desai ◽  
Prakash P. Wadgaonkar

F1000Research ◽  
2016 ◽  
Vol 5 ◽  
pp. 2118 ◽  
Author(s):  
Anna J. Simon ◽  
Andrew D. Ellington

Synthetically engineered organisms hold promise for a broad range of medical, environmental, and industrial applications. Organisms can potentially be designed, for example, for the inexpensive and environmentally benign synthesis of pharmaceuticals and industrial chemicals, for the cleanup of environmental pollutants, and potentially even for biomedical applications such as the targeting of specific diseases or tissues. However, the use of synthetically engineered organisms comes with several reasonable safety concerns, one of which is that the organisms or their genes could escape their intended habitats and cause environmental disruption. Here we review key recent developments in this emerging field of synthetic biocontainment and discuss further developments that might be necessary for the widespread use of synthetic organisms. Specifically, we discuss the history and modern development of three strategies for the containment of synthetic microbes: addiction to an exogenously supplied ligand; self-killing outside of a designated environment; and self-destroying encoded DNA circuitry outside of a designated environment.


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