Toward autonomous materials research: Recent progress and future challenges

2022 ◽  
Vol 9 (1) ◽  
pp. 011405
Author(s):  
Joseph H. Montoya ◽  
Muratahan Aykol ◽  
Abraham Anapolsky ◽  
Chirranjeevi B. Gopal ◽  
Patrick K. Herring ◽  
...  
Coatings ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 110
Author(s):  
Mir Saman Safavi ◽  
Frank C. Walsh ◽  
Maria A. Surmeneva ◽  
Roman A. Surmenev ◽  
Jafar Khalil-Allafi

Hydroxyapatite has become an important coating material for bioimplants, following the introduction of synthetic HAp in the 1950s. The HAp coatings require controlled surface roughness/porosity, adequate corrosion resistance and need to show favorable tribological behavior. The deposition rate must be sufficiently fast and the coating technique needs to be applied at different scales on substrates having a diverse structure, composition, size, and shape. A detailed overview of dry and wet coating methods is given. The benefits of electrodeposition include controlled thickness and morphology, ability to coat a wide range of component size/shape and ease of industrial processing. Pulsed current and potential techniques have provided denser and more uniform coatings on different metallic materials/implants. The mechanism of HAp electrodeposition is considered and the effect of operational variables on deposit properties is highlighted. The most recent progress in the field is critically reviewed. Developments in mineral substituted and included particle, composite HAp coatings, including those reinforced by metallic, ceramic and polymeric particles; carbon nanotubes, modified graphenes, chitosan, and heparin, are considered in detail. Technical challenges which deserve further research are identified and a forward look in the field of the electrodeposited HAp coatings is taken.


2020 ◽  
Vol 21 (1) ◽  
pp. 323-332
Author(s):  
Arif Md. Rashedul Kabir ◽  
Daisuke Inoue ◽  
Akira Kakugo

2015 ◽  
Vol 18 (2) ◽  
pp. 194-213 ◽  
Author(s):  
Qi Hao Zhang ◽  
Xiang Yang Huang ◽  
Sheng Qiang Bai ◽  
Xun Shi ◽  
Ctirad Uher ◽  
...  

MRS Bulletin ◽  
2005 ◽  
Vol 30 (9) ◽  
pp. 635-639 ◽  
Author(s):  
Theresa M. Reineke ◽  
Mark W. Grinstaff

AbstractThe Human Genome Project continues to reveal the genetic basis for numerous acquired and inherited diseases ranging from cancer, HIV, and heart disease to muscular dystrophy and hemophilia. With this wealth of information, the ability to design patient-specific drugs that alter the cellular machinery at the genetic level in a way that controls or treats a specific disease will increasingly become a reality. Designing nucleic acid drugs as well as engineering novel delivery vehicles that encapsulate and effectively transport genetic materials into cells provides an opportunity to enhance the understanding of disease mechanisms and may help treat or cure these diseases. This issue of MRS Bulletin on “Designer Materials for Nucleic Acid Delivery” explores the diverse materials—polymers, lipids, nanoparticles, biocompatible scaffolds, and engineered peptides—that are being evaluated for the intracellular delivery of nucleic acids. These synthetic delivery systems are actively being investigated for many research purposes that range from gene-based therapy, genetic vaccine, and RNA interference to gene function and cellular signaling studies. This area is currently being pursued by a broad group of academic, clinical, and industrial researchers at both the fundamental and applied level, motivated by the widespread implications for human health. In this introductory article, we provide a general tutorial to gene-based therapies and a brief overview of the many areas of materials research that are currently making a tremendous impact on this interdisciplinary field.We conclude with a discussion of the future challenges that materials researchers face in developing viable nucleic acid delivery vehicles.


2010 ◽  
Vol 14 (4) ◽  
pp. 389-399 ◽  
Author(s):  
Mellisa Ly ◽  
Tatiana N. Laremore ◽  
Robert J. Linhardt

2010 ◽  
Vol 16 (3) ◽  
pp. 496-513 ◽  
Author(s):  
Julian D. Olden ◽  
Mark J. Kennard ◽  
Fabien Leprieur ◽  
Pablo A. Tedesco ◽  
Kirk O. Winemiller ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document