Breast-feeding and the onset of atopic dermatitis in childhood: A systematic review and meta-analysis of prospective studies

IntroductionPrevalence rates of breastfeeding remain low even though the World Health Organization (WHO) and the American Academy of Pediatrics recommend exclusive breast feeding for the first 6 months of life in combination with appropriate complementary feeding beyond six 6 months of age. There have been several studies that address the implication of drinking animal milk and/or infant formula on children’s health and development when breast feeding is not offered during the first year of life. Vast improvements have been made in infant formula design, which may increase its benefits compared with animal’s milk. The objective of this review is therefore to synthesise the most recent evidence on the effects of the consumption of animal milk compared with infant formula in non-breastfed or mixed breastfed infants aged 6–11 months.Methods and analysisWe will conduct a systematic review and meta-analysis of studies that assessed the effect of animal milk compared with formula or mixed-fed (breastmilk and formula) on infants aged 6–11 months. The primary outcomes of interest include anaemia, gastrointestinal blood loss, weight for age, height for age and weight for height. We will include randomised and non-randomised studies with a control group. We will use the Cochrane risk of bias tools to assess the risk of bias. We will use meta-analysis to pool findings if the identified studies are conceptually homogenous and data are available from more than one study. We will assess the overall quality of evidence using the Grading of Recommendations Assessment, Development, and Evaluation approach.Ethics and disseminationThis is a systematic review, so no patients will be directly involved in the design or development of this study. The findings from this systematic review will be disseminated to relevant patient populations and caregivers and will guide the WHO’s recommendations on formula consumption versus animal milk in infants aged 6–11 months.Trial registration numberCRD42020210925.

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Comparative effectiveness of probiotic strains on the prevention of pediatric atopic dermatitis: a systematic review and network meta‐analysis

Pediatric Allergy and Immunology ◽

10.1111/pai.13514 ◽

2021 ◽

Author(s):

Carol Stephanie C. Tan‐Lim ◽

Natasha Ann R. Esteban‐Ipac ◽

Marysia Stella T. Recto ◽

Mary Anne R. Castor ◽

Roxanne J. Casis‐Hao ◽

...

Keyword(s):

Systematic Review ◽

Atopic Dermatitis ◽

Comparative Effectiveness ◽

Meta Analysis ◽

Probiotic Strains

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Association Between One-carbon Metabolism-related Vitamins and Risk of Breast Cancer: A Systematic Review and Meta-analysis of Prospective Studies

Clinical Breast Cancer ◽

10.1016/j.clbc.2020.02.012 ◽

2020 ◽

Vol 20 (4) ◽

pp. e469-e480 ◽

Cited By ~ 1

Author(s):

Jie Zeng ◽

Yi Gu ◽

Hongjuan Fu ◽

Chang Liu ◽

Yixin Zou ◽

...

Keyword(s):

Breast Cancer ◽

Systematic Review ◽

Prospective Studies ◽

Carbon Metabolism ◽

Meta Analysis ◽

One Carbon Metabolism

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The association between atopic dermatitis and hand eczema: a systematic review and meta‐analysis

British Journal of Dermatology ◽

10.1111/bjd.16147 ◽

2018 ◽

Vol 178 (4) ◽

pp. 879-888 ◽

Cited By ~ 21

Author(s):

S.M.D. Ruff ◽

K.A. Engebretsen ◽

C. Zachariae ◽

J.D. Johansen ◽

J.I. Silverberg ◽

...

Keyword(s):

Systematic Review ◽

Atopic Dermatitis ◽

Meta Analysis ◽

Hand Eczema

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Daily sodium consumption and CVD mortality in the general population: systematic review and meta-analysis of prospective studies

Public Health Nutrition ◽

10.1017/s1368980014000949 ◽

2014 ◽

Vol 18 (4) ◽

pp. 695-704 ◽

Cited By ~ 37

Author(s):

Rosana Poggio ◽

Laura Gutierrez ◽

María G Matta ◽

Natalia Elorriaga ◽

Vilma Irazola ◽

...

Keyword(s):

Systematic Review ◽

Relative Risk ◽

General Population ◽

Prospective Studies ◽

Meta Analysis ◽

Cochrane Library ◽

Random Effects Models ◽

Meta Regression ◽

Cvd Mortality

AbstractObjectiveThe purpose of the present study was to determine whether elevated dietary Na intake could be associated with CVD mortality.DesignWe performed a systematic review and meta-analysis of prospective studies representing the general population. The adjusted relative risks and their 95 % confidence intervals were pooled by the inverse variance method using random-effects models. Heterogeneity, publication bias, subgroup and meta-regression analyses were performed.SettingsMEDLINE (since 1973), Embase (since 1975), the Cochrane Library (since 1976), ISI Web of Science, Google Scholar (until September 2013) and secondary referencing were searched for inclusion in the study.SubjectEleven prospective studies with 229 785 participants and average follow-up period of 13·37 years (range 5·5–19 years).ResultsHigher Na intake was significantly associated with higher CVD mortality (relative risk=1·12; 95 % CI 1·06, 1·19). In the sensitivity analysis, the exclusion of studies with important relative weights did not significantly affect the results (relative risk=1·08; 95 % CI 1·01, 1·15). The meta-regression analysis showed that for every increase of 10 mmol/d in Na intake, CVD mortality increased significantly by 1 % (P=0·016). Age, hypertensive status and length of follow-up were also associated with increased CVD mortality.ConclusionsHigher Na intake was associated with higher CVD mortality in the general population; this result suggests a reduction in Na intake to prevent CVD mortality from any cause.

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