scholarly journals Detecting quantitative trait loci affecting beef tenderness on bovine chromosome 7 near calpastatin and lysyl oxidase

2006 ◽  
Vol 46 (2) ◽  
pp. 159 ◽  
Author(s):  
R. D. Drinkwater ◽  
Y. Li ◽  
I. Lenane ◽  
G. P. Davis ◽  
R. Shorthose ◽  
...  
Keyword(s):  
Standard Deviation ◽  
Quantitative Trait Loci ◽  
Quantitative Trait ◽  
Lysyl Oxidase ◽  
Bovine Chromosome ◽  
Chromosome 7 ◽  
Meat Tenderness ◽  
Allele Substitution ◽  
Phenotypic Standard Deviation ◽  
Longissimus Lumborum

From a study of 3 large half-sib families of cattle, we describe linkage between DNA polymorphisms on bovine chromosome 7 and meat tenderness. Quantitative trait loci (QTL) for Longissimus lumborum peak force (LLPF) and Semitendonosis adhesion (STADH) were located to this map of DNA markers, which includes the calpastatin (CAST) and lysyl oxidase (LOX) genes. The LLPF QTL has a maximum lodscore of 4.9 and allele substitution of approximately 0.80 of a phenotypic standard deviation, and the peak is located over the CAST gene. The STADH QTL has a maximum lodscore of 3.5 and an allele substitution of approximately 0.37 of a phenotypic standard deviation, and the peak is located over the LOX gene. This suggests 2 separate likelihood peaks on the chromosome. Further analyses of meat tenderness measures in the Longissimus lumborum, LLPF and LL compression (LLC), in which outlier individuals or kill groups are removed, demonstrate large shifts in the location of LLPF QTL, as well as confirming that there are indeed 2 QTL on bovine chromosome 7. We found that both QTL are reflected in both LLPF and LLC measurements, suggesting that both these components of tenderness, myofibrillar and connective tissue, are detected by both measurements in this muscle.

scholarly journals Genetic mapping of quantitative trait loci influencing left ventricular mass in rats

2000 ◽  
Vol 279 (5) ◽  
pp. H2062-H2067 ◽  
Author(s):  
Yasuyuki Tsujita ◽  
Naoharu Iwai ◽  
Shinji Tamaki ◽  
Yasuyuki Nakamura ◽  
Masato Nishimura ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Quantitative Trait Loci ◽  
Left Ventricular Mass ◽  
Quantitative Trait ◽  
Left Ventricular ◽  
Chromosome 7 ◽  
Male Rats ◽  
Chromosome 17 ◽  
Ventricular Mass ◽  
Trait Loci

High blood pressure is the leading cause of left ventricular hypertrophy (LVH); however, not all hypertensive patients develop LVH. Genetic factors are important in the development of LVH. With the use of F2 male rats from spontaneously hypertensive rats and Lewis rats, we performed a study to identify the quantitative trait loci (QTL) that influence left ventricular mass (LVM). Mean arterial pressure (MAP) was measured by the direct intra-arterial method in conscious animals, and LVM was determined at 24 wk of age. QTL analysis was done using 160 microsatellite markers for a genome-wide scan. Two loci that influenced body weight-adjusted LVM with logarithm of the odds scores >3.4 were found. One locus on chromosome 17 influenced LVM independently of MAP. Another locus on chromosome 7 influenced LVM and MAP. These findings indicate not only the existence of a gene on chromosome 7 that influences LVM in a manner dependent on blood pressure but also the existence of a gene on chromosome 17 that influences LVM independently of blood pressure.

Fine mapping of quantitative trait loci for mastitis resistance on bovine chromosome 11

2009 ◽  
Vol 40 (4) ◽  
pp. 509-515 ◽  
Author(s):  
N. F. Schulman ◽  
G. Sahana ◽  
T. Iso-Touru ◽  
M. S. Lund ◽  
L. Andersson-Eklund ◽  
...  
Keyword(s):  
Quantitative Trait Loci ◽  
Fine Mapping ◽  
Quantitative Trait ◽  
Bovine Chromosome ◽  
Chromosome 11 ◽  
Trait Loci

scholarly journals Quantitative trait loci affecting milk production traits on bovine chromosome 6 in zebuine Gyr breed

2011 ◽  
Vol 94 (2) ◽  
pp. 971-980 ◽  
Author(s):  
A.A. Silva ◽  
A.L.S. Azevedo ◽  
R.S. Verneque ◽  
K. Gasparini ◽  
M.G.C.D. Peixoto ◽  
...  
Keyword(s):  
Quantitative Trait Loci ◽  
Milk Production ◽  
Quantitative Trait ◽  
Bovine Chromosome ◽  
Chromosome 6 ◽  
Production Traits ◽  
Milk Production Traits ◽  
Trait Loci

Quantitative trait loci on barley (Hordeum vulgare L.) chromosome 7 associated with components of winterhardiness

Genome ◽  
1993 ◽  
Vol 36 (1) ◽  
pp. 66-71 ◽  
Author(s):  
P. M. Hayes ◽  
T. Blake ◽  
T. H. H. Chen ◽  
S. Tragoonrung ◽  
F. Chen ◽  
...  
Keyword(s):  
Quantitative Trait Loci ◽  
Hordeum Vulgare ◽  
Cold Tolerance ◽  
Quantitative Trait ◽  
Growth Habit ◽  
Genome Mapping ◽  
Chromosome 7 ◽  
Hordeum Vulgare L ◽  
Trait Loci ◽  
Qtl Effects

Quantitative trait loci (QTL) controlling traits associated with winterhardiness in barley (field survival, LT50, growth habit, and crown fructan content) were mapped to chromosome 7 in a population of 100 F1-derived doubled haploid lines. The largest QTL effects for all traits were detected in a 21% recombination interval on the long arm of chromosome 7. QTL in this region accounted for 37–68% of the variation for three measures of cold tolerance, 47% of the variation for growth habit, and 28% of the variation in crown fructan content. Trait association may be due to linkage rather than pleiotropy.Key words: Hordeum vulgare, genome mapping, quantitative trait loci, winterhardiness, cold tolerance, fructan, growth habit.

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