Binding, internalization, and degradation of low density lipoprotein by normal human fibroblasts and by fibroblasts from a case of homozygous familial hypercholesterolemia.

O. Stein; D. B. Weinstein; Y. Stein; D. Steinberg

doi:10.1073/pnas.73.1.14

Binding, internalization, and degradation of low density lipoprotein by normal human fibroblasts and by fibroblasts from a case of homozygous familial hypercholesterolemia.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.73.1.14 ◽

1976 ◽

Vol 73 (1) ◽

pp. 14-18 ◽

Cited By ~ 53

Author(s):

O. Stein ◽

D. B. Weinstein ◽

Y. Stein ◽

D. Steinberg

Keyword(s):

Familial Hypercholesterolemia ◽

Low Density Lipoprotein ◽

Human Fibroblasts ◽

Density Lipoprotein ◽

Low Density ◽

Homozygous Familial Hypercholesterolemia ◽

Normal Human

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Localization of low density lipoprotein receptors on plasma membrane of normal human fibroblasts and their absence in cells from a familial hypercholesterolemia homozygote.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.73.7.2434 ◽

1976 ◽

Vol 73 (7) ◽

pp. 2434-2438 ◽

Cited By ~ 159

Author(s):

R. G. Anderson ◽

J. L. Goldstein ◽

M. S. Brown

Keyword(s):

Plasma Membrane ◽

Familial Hypercholesterolemia ◽

Low Density Lipoprotein ◽

Human Fibroblasts ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptors ◽

Normal Human ◽

In Cells

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Esterification of Low Density Lipoprotein Cholesterol in Human Fibroblasts and Its Absence in Homozygous Familial Hypercholesterolemia

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.71.11.4288 ◽

1974 ◽

Vol 71 (11) ◽

pp. 4288-4292 ◽

Cited By ~ 161

Author(s):

J. L. Goldstein ◽

S. E. Dana ◽

M. S. Brown

Keyword(s):

Familial Hypercholesterolemia ◽

Low Density Lipoprotein ◽

Human Fibroblasts ◽

Density Lipoprotein ◽

Lipoprotein Cholesterol ◽

Low Density ◽

Homozygous Familial Hypercholesterolemia ◽

Low Density Lipoprotein Cholesterol

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Homozygous familial hypercholesterolemia in a young woman with dual gene mutations of low-density lipoprotein receptor and proprotein convertase subtilisin/kexin type 9

Journal of Clinical Lipidology ◽

10.1016/j.jacl.2020.01.009 ◽

2020 ◽

Vol 14 (2) ◽

pp. 192-196

Author(s):

Patrizia Suppressa ◽

Concetta Carbonara ◽

Natasha Scialpi ◽

Alessandro Ciavarella ◽

Carlo Sabbà

Keyword(s):

Familial Hypercholesterolemia ◽

Young Woman ◽

Low Density Lipoprotein ◽

Gene Mutations ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Homozygous Familial Hypercholesterolemia ◽

Proprotein Convertase ◽

Density Lipoprotein Receptor

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Decreased production of low density lipoprotein by atorvastatin after apheresis in homozygous familial hypercholesterolemia

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)37137-6 ◽

1997 ◽

Vol 38 (10) ◽

pp. 2071-2078

Author(s):

A D Marais ◽

R P Naoumova ◽

J C Firth ◽

C Penny ◽

C K Neuwirth ◽

...

Keyword(s):

Familial Hypercholesterolemia ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Homozygous Familial Hypercholesterolemia

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Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor)

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.117.310217 ◽

2018 ◽

Vol 38 (3) ◽

pp. 592-598 ◽

Cited By ~ 32

Author(s):

Aurélie Thedrez ◽

Dirk J. Blom ◽

Stéphane Ramin-Mangata ◽

Valentin Blanchard ◽

Mikaël Croyal ◽

...

Keyword(s):

Familial Hypercholesterolemia ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Homozygous Familial Hypercholesterolemia ◽

Low Density Lipoprotein Receptor ◽

Density Lipoprotein Receptor

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Three different schedules of low-density lipoprotein apheresis compared with plasmapheresis in patients with homozygous familial hypercholesterolemia

The American Journal of Medicine ◽

10.1016/0002-9343(90)90455-m ◽

1990 ◽

Vol 88 (2) ◽

pp. 94-100 ◽

Cited By ~ 16

Author(s):

G. Michael Berger ◽

Jean C. Firth ◽

Peter Jacobs ◽

Lucille Wood ◽

A. David Marais ◽

...

Keyword(s):

Familial Hypercholesterolemia ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Homozygous Familial Hypercholesterolemia ◽

Lipoprotein Apheresis

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27-Hydroxylated Low Density Lipoprotein (LDL) Cholesterol Can Be Converted to 7α,27-Dihydroxy-4-cholesten-3-one (Cytosterone) before Suppressing Cholesterol Production in Normal Human Fibroblasts

Journal of Biological Chemistry ◽

10.1074/jbc.271.22.12724 ◽

1996 ◽

Vol 271 (22) ◽

pp. 12724-12736 ◽

Cited By ~ 27

Author(s):

Magnus Axelson ◽

Olle Larsson

Keyword(s):

Ldl Cholesterol ◽

Low Density Lipoprotein ◽

Human Fibroblasts ◽

Density Lipoprotein ◽

Low Density ◽

Normal Human

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Identification of a New Mutation, S305C, in Exon 7 of the Low-Density Lipoprotein Receptor Gene in a Brazilian Family with Homozygous Familial Hypercholesterolemia

Genetic Testing ◽

10.1089/109065703321560994 ◽

2003 ◽

Vol 7 (1) ◽

pp. 77-79 ◽

Cited By ~ 2

Author(s):

Laura van de Kerkhof ◽

Silvia J. Van Eijk ◽

Joep C. Defesche ◽

José-Ernesto Dos-Santos

Keyword(s):

Familial Hypercholesterolemia ◽

Receptor Gene ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Homozygous Familial Hypercholesterolemia ◽

Low Density Lipoprotein Receptor ◽

New Mutation ◽

Density Lipoprotein Receptor

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Oxidative structural modifications of low density lipoprotein in homozygous familial hypercholesterolemia

Atherosclerosis ◽

10.1016/0021-9150(95)05612-2 ◽

1995 ◽

Vol 118 (2) ◽

pp. 259-273 ◽

Cited By ~ 42

Author(s):

Claudio Napoli ◽

Alfredo Postiglione ◽

Massimo Triggiani ◽

Gaetano Corso ◽

Giuseppe Palumbo ◽

...

Keyword(s):

Familial Hypercholesterolemia ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Homozygous Familial Hypercholesterolemia ◽

Structural Modifications

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Hemostatic variables in homozygous familial hypercholesterolemia. Effect of regular plasma cholesterol removal by low density lipoprotein apheresis.

Arteriosclerosis An Official Journal of the American Heart Association Inc ◽

10.1161/01.atv.10.6.1119 ◽

1990 ◽

Vol 10 (6) ◽

pp. 1119-1126 ◽

Cited By ~ 15

Author(s):

G Di Minno ◽

A M Cerbone ◽

F Cirillo ◽

A Postiglione ◽

M Colucci ◽

...

Keyword(s):

Familial Hypercholesterolemia ◽

Plasma Cholesterol ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Homozygous Familial Hypercholesterolemia ◽

Cholesterol Removal ◽

Lipoprotein Apheresis

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