scholarly journals Regulation of viral transciption and tumor antigen expression in cells transformed by simian virus 40.

1976 ◽  
Vol 73 (6) ◽  
pp. 1931-1935 ◽  
Author(s):  
C. Basilico ◽  
D. Zouzias
Keyword(s):  
Tumor Antigen ◽  
Simian Virus 40 ◽  
Antigen Expression ◽  
Simian Virus ◽  
Tumor Antigen Expression ◽  
In Cells

scholarly journals In vitro simian virus 40 large tumor antigen expression correlates with differential immune responses following DNA immunization

Virology ◽  
2005 ◽  
Vol 332 (1) ◽  
pp. 28-37 ◽  
Author(s):  
Devin B. Lowe ◽  
Michael H. Shearer ◽  
James A. Tarbox ◽  
Hyun Seok Kang ◽  
Cynthia A. Jumper ◽  
...  
Keyword(s):  
Immune Responses ◽  
Tumor Antigen ◽  
Simian Virus 40 ◽  
Antigen Expression ◽  
Simian Virus ◽  
Dna Immunization ◽  
Large Tumor ◽  
Large Tumor Antigen ◽  
Tumor Antigen Expression

scholarly journals Simian virus 40 tumor antigen expression and immunophenotypic profile of AIDS-related non-Hodgkin's lymphoma

Virology ◽  
2005 ◽  
Vol 342 (1) ◽  
pp. 38-46 ◽  
Author(s):  
Regis A. Vilchez ◽  
Dolores Lopez-Terrada ◽  
John R. Middleton ◽  
Chris J. Finch ◽  
Deanna E. Killen ◽  
...  
Keyword(s):  
Tumor Antigen ◽  
Hodgkin’S Lymphoma ◽  
Simian Virus 40 ◽  
Antigen Expression ◽  
Simian Virus ◽  
Hodgkin's Lymphoma ◽  
Non Hodgkin’S Lymphoma ◽  
Non Hodgkin's Lymphoma ◽  
Tumor Antigen Expression

Relationship between simian virus 40 large tumor antigen expression and tumor formation in transgenic mice.

1987 ◽  
Vol 61 (6) ◽  
pp. 2029-2032 ◽  
Author(s):  
T A Van Dyke ◽  
C Finlay ◽  
D Miller ◽  
J Marks ◽  
G Lozano ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Tumor Antigen ◽  
Simian Virus 40 ◽  
Antigen Expression ◽  
Simian Virus ◽  
Tumor Formation ◽  
Large Tumor ◽  
Large Tumor Antigen ◽  
Tumor Antigen Expression

Expression of the mouse p53 cellular tumor antigen in monkey cells

1984 ◽  
Vol 4 (10) ◽  
pp. 2180-2186
Author(s):  
O Pinhasi ◽  
M Oren
Keyword(s):  
Tumor Antigen ◽  
Recombinant Dna ◽  
Simian Virus 40 ◽  
Simian Virus ◽  
T Antigen ◽  
Transformed Cells ◽  
Reading Frame ◽  
Recombinant Plasmids ◽  
Cos Cells ◽  
In Cells

DNA specific for the murine p53 cellular tumor antigen was linked to the early simian virus 40 promoter and introduced into monkey COS cells either by transfection with recombinant plasmids or by infection with virus. Recipient cells made substantial amounts of a protein apparently identical to mouse p53. Severalfold-larger quantities were detected when cells were transfected with an intron-containing p53-specific segment, as compared with transfection with intronless cDNA. The p53 encoded by the recombinant DNA was capable of complexing with the simian virus 40 T antigen. Transfected p53 was also probably associated with a cellular 68-kilodalton protein, which may be related to a protein coprecipitating with p53 in some transformed cells. These findings confirm the predicted reading frame and protein boundaries and demonstrate that apparently functional p53 can be produced in cells via experimentally introduced recombinant DNA.

scholarly journals Expression of the mouse p53 cellular tumor antigen in monkey cells.

1984 ◽  
Vol 4 (10) ◽  
pp. 2180-2186 ◽  
Author(s):  
O Pinhasi ◽  
M Oren
Keyword(s):  
Tumor Antigen ◽  
Recombinant Dna ◽  
Simian Virus 40 ◽  
Simian Virus ◽  
T Antigen ◽  
Transformed Cells ◽  
Reading Frame ◽  
Recombinant Plasmids ◽  
Cos Cells ◽  
In Cells

DNA specific for the murine p53 cellular tumor antigen was linked to the early simian virus 40 promoter and introduced into monkey COS cells either by transfection with recombinant plasmids or by infection with virus. Recipient cells made substantial amounts of a protein apparently identical to mouse p53. Severalfold-larger quantities were detected when cells were transfected with an intron-containing p53-specific segment, as compared with transfection with intronless cDNA. The p53 encoded by the recombinant DNA was capable of complexing with the simian virus 40 T antigen. Transfected p53 was also probably associated with a cellular 68-kilodalton protein, which may be related to a protein coprecipitating with p53 in some transformed cells. These findings confirm the predicted reading frame and protein boundaries and demonstrate that apparently functional p53 can be produced in cells via experimentally introduced recombinant DNA.

scholarly journals Simian virus 40 maturation in cells harboring mutants deleted in the agnogene.

1985 ◽  
Vol 260 (2) ◽  
pp. 1127-1132
Author(s):  
S C Ng ◽  
J E Mertz ◽  
S Sanden-Will ◽  
M Bina
Keyword(s):  
Simian Virus 40 ◽  
Simian Virus ◽  
In Cells
Sign in / Sign up

Export Citation Format

Share Document