scholarly journals In vivo protein-DNA interactions at human DNA replication origin.

1996 ◽  
Vol 93 (4) ◽  
pp. 1498-1503 ◽  
Author(s):  
D. S. Dimitrova ◽  
M. Giacca ◽  
F. Demarchi ◽  
G. Biamonti ◽  
S. Riva ◽  
...  
Keyword(s):  
Dna Replication ◽  
Replication Origin ◽  
Dna Interactions ◽  
Human Dna ◽  
Protein Dna Interactions ◽  
Dna Replication Origin

A human DNA replication origin: localization and transcriptional characterization

Chromosoma ◽  
1992 ◽  
Vol 102 (S1) ◽  
pp. S24-S31 ◽  
Author(s):  
Giuseppe Biamonti ◽  
Giovanni Perini ◽  
Florian Weighardt ◽  
Silvano Riva ◽  
Mauro Giacca ◽  
...  
Keyword(s):  
Dna Replication ◽  
Replication Origin ◽  
Human Dna ◽  
Dna Replication Origin

A DNA replication origin and a replication fork barrier used in vivo in the circular plasmid pKD1

2001 ◽  
Vol 266 (2) ◽  
pp. 326-335 ◽  
Author(s):  
L. Fabiani ◽  
C. Irene ◽  
M. Aragona ◽  
C. Newlon
Keyword(s):  
Dna Replication ◽  
Replication Origin ◽  
Replication Fork ◽  
Circular Plasmid ◽  
Dna Replication Origin

Selection of homeotic proteins for binding to a human DNA replication origin 1 1Edited by M. Yaniv

2000 ◽  
Vol 299 (3) ◽  
pp. 667-680 ◽  
Author(s):  
Elisa de Stanchina ◽  
Davide Gabellini ◽  
Paolo Norio ◽  
Mauro Giacca ◽  
Fiorenzo A Peverali ◽  
...  
Keyword(s):  
Dna Replication ◽  
Replication Origin ◽  
Human Dna ◽  
Dna Replication Origin ◽  
Selection Of

Sequence and structural requirements of a herpes simplex viral DNA replication origin

1988 ◽  
Vol 8 (10) ◽  
pp. 4018-4027
Author(s):  
D Lockshon ◽  
D A Galloway
Keyword(s):  
Dna Replication ◽  
Herpes Simplex ◽  
Replication Origin ◽  
Base Pairs ◽  
The Core ◽  
Dna Replication Origin ◽  
Origin Function ◽  
Simplex Virus

Herpes simplex virus (HSV) types 1 and 2 contain two classes of origins of DNA replication, oriS and oriL, which are closely related. A series of plasmids was constructed which contained specifically altered versions of the HSV type 2 oriS replication origin. Their ability to replicate in an in vivo replicon assay allowed a core origin of 75 base pairs (bp) to be defined. It included both arms of a 56-bp palindrome and from 13 to 20 bp of sequence leftward of the palindrome. The AT-rich sequence at the center of the palindrome was essential. Sequences on either side of the core origin enhanced replication. When additional copies of the -AT-dinucleotide were introduced progressively into the center of the palindrome, an oscillating effect on origin function was observed. These and other data implicate a linear rather than a cruciform conformation of the oriS palindrome in the initiation of HSV replication.

scholarly journals Sequence and structural requirements of a herpes simplex viral DNA replication origin.

1988 ◽  
Vol 8 (10) ◽  
pp. 4018-4027 ◽  
Author(s):  
D Lockshon ◽  
D A Galloway
Keyword(s):  
Dna Replication ◽  
Herpes Simplex ◽  
Replication Origin ◽  
Base Pairs ◽  
The Core ◽  
Dna Replication Origin ◽  
Origin Function ◽  
Simplex Virus

Herpes simplex virus (HSV) types 1 and 2 contain two classes of origins of DNA replication, oriS and oriL, which are closely related. A series of plasmids was constructed which contained specifically altered versions of the HSV type 2 oriS replication origin. Their ability to replicate in an in vivo replicon assay allowed a core origin of 75 base pairs (bp) to be defined. It included both arms of a 56-bp palindrome and from 13 to 20 bp of sequence leftward of the palindrome. The AT-rich sequence at the center of the palindrome was essential. Sequences on either side of the core origin enhanced replication. When additional copies of the -AT-dinucleotide were introduced progressively into the center of the palindrome, an oscillating effect on origin function was observed. These and other data implicate a linear rather than a cruciform conformation of the oriS palindrome in the initiation of HSV replication.

Sequence-specific DNA binding protein(s) that bind(s) to a putative human DNA replication origin

1988 ◽  
Vol 37 (9) ◽  
pp. 1807-1808 ◽  
Author(s):  
M. Giacca ◽  
G. Biamonti ◽  
F. Cobianchi ◽  
M. Colonna ◽  
C. Tribioli ◽  
...  
Keyword(s):  
Dna Replication ◽  
Dna Binding ◽  
Replication Origin ◽  
Binding Protein ◽  
Protein S ◽  
Dna Binding Protein ◽  
Human Dna ◽  
Dna Replication Origin
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