scholarly journals A Phage Display Screen and Binding Studies with Acetylated Low Density Lipoprotein Provide Evidence for the Importance of the Scavenger Receptor Cysteine-rich (SRCR) Domain in the Ligand-binding Function of MARCO

2006 ◽  
Vol 281 (18) ◽  
pp. 12767-12775 ◽  
Author(s):  
Yunying Chen ◽  
Marko Sankala ◽  
Juha R. M. Ojala ◽  
Yi Sun ◽  
Ari Tuuttila ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Phage Display ◽  
Low Density Lipoprotein ◽  
Scavenger Receptor ◽  
Density Lipoprotein ◽  
Low Density ◽  
Binding Studies ◽  
Srcr Domain ◽  
Binding Function

scholarly journals CXCL16 Is Expressed in Podocytes and Acts as a Scavenger Receptor for Oxidized Low-Density Lipoprotein

2009 ◽  
Vol 174 (6) ◽  
pp. 2061-2072 ◽  
Author(s):  
Paul Gutwein ◽  
Mohamed Sadek Abdel-Bakky ◽  
Anja Schramme ◽  
Kai Doberstein ◽  
Nicole Kämpfer-Kolb ◽  
...  
Keyword(s):  
Low Density Lipoprotein ◽  
Scavenger Receptor ◽  
Density Lipoprotein ◽  
Low Density ◽  
Oxidized Low Density Lipoprotein

scholarly journals Endocytosis of formaldehyde-treated serum albumin via scavenger pathway in liver endothelial cells

1984 ◽  
Vol 218 (1) ◽  
pp. 81-86 ◽  
Author(s):  
R Blomhoff ◽  
W Eskild ◽  
T Berg
Keyword(s):  
Endothelial Cells ◽  
Low Density Lipoprotein ◽  
Scavenger Receptor ◽  
Density Lipoprotein ◽  
Low Density ◽  
Surface Culture ◽  
Rat Liver Cells ◽  
Liver Endothelial Cells ◽  
Isolated Liver

Denatured or modified proteins (including albumin and low-density lipoprotein) are catabolized in vitro via scavenger receptors. We have studied the distribution of formaldehyde-denatured albumin in rat liver cells after intravenous injection of tracer doses of the protein. At 12 min after injection, most of the formaldehyde-denatured albumin (about 70% of the injected dose) was recovered in liver endothelial cells. Furthermore, isolated liver endothelial cells in suspension and in surface culture took up formaldehyde-denatured albumin by receptor-mediated endocytosis. Our data indicate that the scavenger receptor in liver is mainly located on the endothelial cells. Implications for the catabolism of low-density lipoproteins are discussed.

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