Effects of topical drops and sprays on mucociliary transport time and nasal air flow

2009 ◽  
pp. 1-5 ◽  
Author(s):  
Sami Bercin ◽  
Ahmet Ural ◽  
Ahmet Kutluhan
Keyword(s):  
Air Flow ◽  
Mucociliary Transport ◽  
Transport Time

Effects of topical drops and sprays on mucociliary transport time and nasal air flow

2009 ◽  
Vol 129 (11) ◽  
pp. 1257-1261 ◽  
Author(s):  
Sami Bercin ◽  
Ahmet Ural ◽  
Ahmet Kutluhan
Keyword(s):  
Air Flow ◽  
Mucociliary Transport ◽  
Transport Time

scholarly journals Efektivitas salin hipertonik terhadap waktu transpor mukosiliar dan skor gejala hidung penderita rinitis alergi

2018 ◽  
Vol 47 (2) ◽  
pp. 123
Author(s):  
Woro Safitri ◽  
Dwi Reno Pawarti ◽  
Titiek Hidayati Ahadiah
Keyword(s):  
Clinical Trial ◽  
Allergic Rhinitis ◽  
Symptom Score ◽  
Saline Group ◽  
Nasal Symptom ◽  
Control Group ◽  
Mucociliary Transport ◽  
Transport Time ◽  
Total Nasal Symptom Score ◽  
The Mean

Latar belakang: Rinitis alergi (RA) adalah suatu penyakit inflamasi mukosa hidung yang diperantara oleh imunoglobulin E (IgE), setelah mukosa hidung terpapar alergen. Tujuan: Mengidentifikasi efektivitas cuci hidung salin hipertonik terhadap waktu transpor mukosiliar dan skor gejala hidung total (SGHT) pada penderita RA. Metode: Penelitian dilaksanakan pada bulan Juli hingga Desember 2016 di Poli Telinga Hidung Tenggorok – Bedah Kepala Leher Rumah Sakit Dr. Soetomo Surabaya. Uji klinis acak terkontrol pada 2 kelompok dengan desain control group in clinical trial. Pengambilan sampel dilakukan secara consecutive sampling. Uji korelasi yang digunakan adalah uji t berpasangan dan uji Wilcoxon. Hasil: Didapatkan sampel 42 penderita, yaitu 21 penderita pada kelompok loratadin, serta 21 penderita pada kelompok loratadin dan cuci hidung salin hipertonik. Didapatkan rerata penurunan transpor mukosiliar kelompok loratadin dan cuci hidung salin hipertonik lebih bermakna daripada kelompok loratadin (p=0,001). Penurunan transpor mukosiliar kelompok loratadin didapatkan rerata -2,30 (SD=2,77), kelompok loratadin dan cuci hidung salin hipertonik didapatkan rerata -6,27 (SD=3,91). Penurunan SGHT kelompok loratadin didapatkan rerata -2,48 (SD=1,72), sedangkan kelompok loratadin dan cuci hidung salin hipertonik didapatkan rerata -4,3 (SD=1,20). Kesimpulan: Penambahan cuci hidung salin hipertonik pada terapi loratadin lebih efektif dibandingkan terapi tunggal loratadin dalam menurunkan transpor mukosiliar dan SGHT pada penderita RA. Kata kunci: Loratadin, cuci hidung salin hipertonik, transpor mukosiliar, skor gejala hidung total, rinitis alergi ABSTRACT Background: Allergic rhinitis (AR) is a nasal mucous membrane inflamatory which mediated by Imunoglobulin E (IgE) after allergen exposure in nasal mucosa. Purpose: To identify the effectiveness of nasal hypertonic saline irrigation on reduction of mucociliary transport time (MCTT) and total nasal symptom score (TNSS) in AR patients. Methods: The was conducted from July until December 2016 in Oto Rhino Laryngology - Head and Neck Surgery of Dr. Soetomo Hospital Surabaya. The study was randomized controlled clinical trials on two groups, with the control group in clinical trial design. Paired t and Wilcoxon test was used as the correlation test. Results: There was 42 patients, 21 patients in loratadine group, and 21 patients in loratadine with hypertonic nasal saline group. The average of mucociliary transport time decrease of loratadine with hypertonic nasal saline group was more significant than loratadine group (p=0.001). The mean of decreasing mucociliary transport time in loratadine group was -2.30 (SD=2.77) and loratadine with hypertonic nasal saline group was -6.27 (SD=3.91). The mean of decreasing TNSS in loratadin group was -2.48 (SD=1.72), and loratadin with hypertonic nasal saline group was -4.3 (SD=1.20). Conclusions: The addition of hypertonic nasal saline in loratadine was more effective, compared to monotherapy of loratadine in decreasing mucociliary transport time and TNSS in patient with AR. Keywords: Loratadine, hypertonic nasal saline, mucociliary transport, total nasal symptom score, allergic rhinitis

The Role of Rhinomanometry, Acoustic Rhinometry, and Mucociliary Transport Time in the Assessment of Nasal Patency

2000 ◽  
Vol 79 (5) ◽  
pp. 397-400 ◽  
Author(s):  
Desiderio Passàli ◽  
Chiara Mezzedimi ◽  
Giulio Cesare Passàli ◽  
Daniele Nuti ◽  
Luisa Bellussi
Keyword(s):  
Nasal Obstruction ◽  
Acoustic Rhinometry ◽  
Mucociliary Transport ◽  
Nasal Patency ◽  
Analog Scale ◽  
Transport Time ◽  
Subjective Assessments ◽  
Symptom Scores ◽  
Objective Tests

We conducted a study of 60 patients with different nasal pathologies who complained of nasal obstruction. Our goal was to evaluate the reliability of rhinomanometry, acoustic rhinometry, and the measurement of mucociliary transport time in helping make the diagnosis of nasal pathologies. We also sought to discover whether there is a correlation between the findings of these objective tests and the results of patients’ own subjective assessments of nasal obstruction. We found that acoustic rhinometry was more specific and more sensitive than rhinomanometry in diagnosing rhinopathies inpatients with structural anomalies. Symptom scores as rated by patients on the visual analog scale frequently did not correlate with objective measures, as patients often overestimated the severity of their obstruction. However, for a few patients, there was a correlation between symptom scores and mucociliary transport times.

The prognostic value of mucociliary clearance in predicting success in tympanoplasty

1993 ◽  
Vol 107 (10) ◽  
pp. 895-897 ◽  
Author(s):  
F. Giménez ◽  
J. Marco-Algarra
Keyword(s):  
Saccharin Solution ◽  
Prognostic Value ◽  
Mucociliary Clearance ◽  
Mucociliary Transport ◽  
Transport Time ◽  
Failure Group ◽  
Predicting Success ◽  
Cent Sodium ◽  
Success Group ◽  
Normal Transport

AbstractMucociliary and equipressive eustachian tube functions have been studied, using saccharin solution (five per cent sodium saccharinate) and tubal manometry respectively, in 58 ears with chronic disease undergoing tympanoplasty. The position of the perforation site determines the results as the poorest results are obtained from the posterior ones, positive cases (47 per cent) and mean transport time (37.7 minutes), compared to the greater percentage of positive cases (86 per cent) and mean transport time (22.2 minutes) for anterior perforations.When both parameters are analysed together there is a direct relationship between normal equipressive function and normal mucociliary transport time and between negative transport time and tubal blocking. Significant differences in transport times have been found for the anterior and posterior perforations being shorter for the anterior ones.When surgical outcome is correlated with mucociliary transport, the normal transport time percentage is seen to be considerably higher in the success group (50 per cent) than in the failure group (22 per cent).

Influence of topical phenypropanolamine on tachyphylaxis and mucociliary clearance in the human nose

1988 ◽  
Vol 102 (5) ◽  
pp. 408-410 ◽  
Author(s):  
K. Holmberg ◽  
M. Bende
Keyword(s):  
Dose Response ◽  
Mucociliary Clearance ◽  
Mucociliary Transport ◽  
Cent Solution ◽  
Transport Time ◽  
Reduced Dose ◽  
Healthy Humans ◽  
Mucociliary System ◽  
Dose Response Effect ◽  
Human Nose

AbstractTopical nasal phenylpropanolamine in a 2.5 per cent solution (PPA) was used in an evaluation of the possible development of tachyphylaxis and of possible effects on the mucociliary system after one week of treatment in healthy humans. The tendency of PPA to produce tachyphylaxis was evaluated by rhi-nomanometrie measurements of nasal airway resistance after repeated dose-response provocations. The mucociliary transport time was tested with the saccharine-dye test. No reduced dose-response effect or change in mucociliary transport time was found with PPA, thus indicating that one week of treatment does not contribute to such adverse effects.

Experiences in the Determination of Nasal Mucociliary Transport Time

1984 ◽  
Vol 97 (3-4) ◽  
pp. 319-323 ◽  
Author(s):  
D Passàli ◽  
L. Bellussi ◽  
E. De Seta
Keyword(s):  
Mucociliary Transport ◽  
Transport Time

Nasal changes associated with exercise in athletes: systematic review

2018 ◽  
Vol 132 (3) ◽  
pp. 191-197 ◽  
Author(s):  
P Surda ◽  
A Walker ◽  
J Limpens ◽  
W Fokkens ◽  
M Putala
Keyword(s):  
Systematic Review ◽  
Nasal Mucosa ◽  
Strenuous Exercise ◽  
Nasal Airway ◽  
Mucociliary Transport ◽  
Short Term ◽  
Transport Time ◽  
Type Method ◽  
The Impact ◽  
Nasal Changes

AbstractBackground:The prevalence of rhinitis in athletes has frequently been studied in combination with asthma, but the impact of exercise on the paracrine and secretory functions of nasal mucosa is less well established. This systematic review aimed to examine the effect of exercise on nasal mucosa in elite athletes.Method:A systematic search of Medline, Embase and the non-Medline subset of PubMed, from inception to 8th March 2016, was performed to identify studies on rhinitis in athletes.Results:Of the 373 identified unique articles, a total of 8 studies satisfied the criteria for this review.Conclusion:There is no evidence in the existing literature that indicates a reduction in nasal airway induced by exercise. Olfaction and mucociliary transport time are affected in swimmers, which can likely be attributed to chlorine irritation and which resolves with training cessation. Short-term strenuous exercise may trigger changes in cytology and prolonged mucociliary transport time, which also resolve quickly with rest.

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