Direct Determination of Uric Acid Based on Pd Nanoparticles Electrodepositing onto Anatase-Type TiO2Nanoparticles/Chitsan Film-Modified Electrode

Poly(methylene blue) and electrochemically reduced graphene oxide composite film modified electrode (PMB-ERGO/GCE) was successfully fabricated by electropolymerization and was used for simultaneous determination of uric acid (UA) and xanthine (Xa). Based on the excellent electrocatalytic activity of PMB-ERGO/GCE, the electrochemical behaviors of UA and Xa were studied by cyclic voltammetry (CV) and square wave voltammetry (SWV). Two anodic sensitive peaks at 0.630 V (versus Ag/AgCl) for UA and 1.006 V (versus Ag/AgCl) for Xa were given by CV in pH 3.0 phosphate buffer. The calibration curves for UA and Xa were obtained in the range of 8.00 × 10−8~4.00 × 10−4 M and 1.00 × 10−7~4.00 × 10−4 M, respectively, by SWV. The detection limits for UA and Xa were3.00×10-8 M and5.00×10-8 M, respectively. Finally, the proposed method was applied to simultaneously determine UA and Xa in human urine with good selectivity and high sensitivity.

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Electrochemical sensor based on dual-template molecularly imprinted polymer and nanoporous gold leaf modified electrode for simultaneous determination of dopamine and uric acid

Microchimica Acta ◽

10.1007/s00604-020-04413-5 ◽

2020 ◽

Vol 187 (9) ◽

Author(s):

Nan Li ◽

Chuanchuan Nan ◽

Xuecui Mei ◽

Yudong Sun ◽

Huanhuan Feng ◽

...

Keyword(s):

Uric Acid ◽

Electrochemical Sensor ◽

Simultaneous Determination ◽

Modified Electrode ◽

Molecularly Imprinted Polymer ◽

Nanoporous Gold ◽

Imprinted Polymer ◽

Molecularly Imprinted ◽

Gold Leaf

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Fabrication of Graphene/Carbon Nanotube Composite Modified Electrode for Selective and Sensitive Determination of Uric Acid

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.641-642.562 ◽

2013 ◽

Vol 641-642 ◽

pp. 562-565

Author(s):

Zheng Xiao Liu ◽

Jian Fei Xia ◽

Zong Hua Wang ◽

Yan Zhi Xia ◽

Fei Fei Zhang ◽

...

Keyword(s):

Carbon Nanotubes ◽

Uric Acid ◽

Carbon Nanotube ◽

Modified Electrode ◽

Phosphate Buffer Solution ◽

Carbon Electrode ◽

Buffer Solution ◽

Sensitive Determination ◽

Carbon Nanotube Composite

A novel composite was firstly synthesized by compositing graphenes (G) and carbon nanotubes (CNTs) and then a new composite modified electrode (G/CNTs/GCE) was prepared by coating the resulting composite on the surface of the glassy carbon electrode (GCE). The composite modified electrode G/CNTs/GCE showed great electrochemical activities which were studied by sensitive determining the electrochemistry behaviors of uric acid (UA). It revealed when the concentration range of UA changed from 1×10-7 mol/L to 1×10-3 mol/L, the peak currents had linear relationship with the concentration of UA in the phosphate buffer solution (PBS) which the value of pH is 7.0. And the linear equation is ip (μA) = 21.55C+28.94 (C: mmol/L), with the related coefficient 0.9964.

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