Rapid and Highly Sensitive HPLC and TLC Methods for Quantitation of Amlodipine Besilate and Valsartan in Bulk Powder and in Pharmaceutical Dosage Forms and in Human Plasma

2010 ◽  
Vol 43 (4) ◽  
pp. 570-581 ◽  
Author(s):  
Nesrin K. Ramadan ◽  
Heba M. Mohamed ◽  
Azza A. Moustafa
Keyword(s):  
Human Plasma ◽  
Dosage Forms ◽  
Pharmaceutical Dosage Forms ◽  
Bulk Powder ◽  
Highly Sensitive

scholarly journals Core–shell particles and monolithic columns; tools for simultaneous LC analysis of avanafil, sildenafil, apomorphine, trazodone, yohimbine, tramadol and dapoxetine in pharmaceutical dosage forms, counterfeit products and human plasma

RSC Advances ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 1379-1387 ◽  
Author(s):  
Adel Ehab Ibrahim ◽  
Hisham Hashem ◽  
Magda Elhenawee ◽  
Hanaa Saleh
Keyword(s):  
Human Plasma ◽  
Dosage Forms ◽  
Sexual Disorders ◽  
Monolithic Columns ◽  
Core Shell ◽  
Pharmaceutical Dosage Forms ◽  
Shell Particles ◽  
Counterfeit Products

By 2025, it's estimated that 322 million males worldwide will suffer from sexual disorders. This study provides two simple green tools for analysis of some male sexual enhancers using HPLC on core–shell particles and monolithic RP-columns.

scholarly journals SPECTROMETRIC INVESTIGATION OF CEFPROZIL IN BULK POWDER AND IN PHARMACEUTICAL FORMULATIONS

2002 ◽  
Vol 70 (1) ◽  
pp. 67-76 ◽  
Author(s):  
EI-Adl Sobhy M. ◽  
Saleh Hanaa M.
Keyword(s):  
Metal Ion ◽  
Hydrolysis Product ◽  
Reference Method ◽  
Standard Addition ◽  
Pharmaceutical Formulations ◽  
Dosage Forms ◽  
Pharmaceutical Dosage Forms ◽  
Bulk Powder ◽  
Ion Contents

Three accurate methods were developed for the quantitative determination of cefprozil in pure form and in its dosage forms. The first method was based upon the interaction of the drug with 3-methyl-benzothiazolinone-2-hydrazone (MBTH) in the presence of ceric ammonium sulfate or ferric chloride as an oxidizing agent, where the formed color was measured at λ 521 nm or 624 nm, respectively. The second inethod was based on the chelate formation with palladium (II) chloride (PdCl2) in the presence of buffered medium, where the formed complex was determined at λ 345 nm. The third method was based upon the reaction of the neutral solution of the hydrolysis product of drug with each of silver nitrate & lead acetate standard solutions, forming drug-metal complex and the metal ion contents were determined directly or indirectly by atomic absorption spectroscopy (AAS). The reaction conditions of the proposed methods were studied and optimized. The precision of the proposed methods was achieved by determining different samples of bulk powder and pharmaceutical dosage forms. The validity of the methods was assessed by applying the standard addition technique and the results were compared with those obtained by the reference method showing a great agreement

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