ZnCl2 Catalyzed Ring-Opening Reaction of Symmetrical Epoxides with Aromatic Amines for the Synthesis of 1,2-Amino Alcohols

2021 ◽  
pp. 1-9
Author(s):  
Xiao-Yu Zhou ◽  
Xia Chen
Keyword(s):  
Aromatic Amines ◽  
Ring Opening ◽  
Amino Alcohols ◽  
Ring Opening Reaction

scholarly journals Asymmetric ring-opening reaction of meso-epoxides with aromatic amines using homochiral metal–organic frameworks as recyclable heterogeneous catalysts

RSC Advances ◽  
2018 ◽  
Vol 8 (49) ◽  
pp. 28139-28146 ◽  
Author(s):  
Koichi Tanaka ◽  
Maya Kinoshita ◽  
Jun Kayahara ◽  
Yutaro Uebayashi ◽  
Kazusada Nakaji ◽  
...  
Keyword(s):  
Aromatic Amines ◽  
Ring Opening ◽  
Heterogeneous Catalysts ◽  
Metal Organic Framework ◽  
Metal Organic Frameworks ◽  
Amino Alcohols ◽  
Ring Opening Reaction ◽  
Ring Opening Reactions ◽  
Metal Organic ◽  
Asymmetric Ring Opening

Asymmetric ring-opening reactions of meso-epoxides by aromatic amines were achieved by using some chiral metal–organic frameworks. The corresponding β-amino alcohols were obtained with good yields and enantioselectivities (up to 97% ee).

Cadmium chloride-catalyzed regioselective opening of oxiranes with aromatic amines — An improved protocol for the synthesis of 2-amino alcohols

2007 ◽  
Vol 85 (1) ◽  
pp. 37-41 ◽  
Author(s):  
S Ramesh Kumar ◽  
P Leelavathi
Keyword(s):  
Aromatic Amines ◽  
Ring Opening ◽  
Cadmium Chloride ◽  
Room Temperature ◽  
Amino Alcohols ◽  
Reaction Conditions ◽  
Ring Opening Reaction

Epoxides undergo rapid CdCl2-catalyzed ring-opening reaction with aromatic amines in mild reaction conditions (room temperature), affording the corresponding 2-amino alcohols with high regioselectivity.Key words: epoxides, aromatic amines, cadmium chloride, 2-amino alcohols.

scholarly journals Anhydrous Titanium(III) chloride as a New Lewis-Acid Catalyst for Ring Opening of Epoxides with Aromatic Amines

2007 ◽  
Vol 2 (2) ◽  
pp. 1934578X0700200
Author(s):  
Suchitra Bhatt ◽  
Sandip K. Nayak
Keyword(s):  
Ambient Temperature ◽  
Lewis Acid ◽  
Aromatic Amines ◽  
Ring Opening ◽  
Acid Catalyst ◽  
Amino Alcohols ◽  
Azide Ion ◽  
Ring Opening Of Epoxides ◽  
Lewis Acid Catalyst

Anhydrous titanium(III) chloride was found to be a simple and efficient Lewis acid catalyst for ring opening of epoxides at ambient temperature. The reaction proceeded smoothly with anilines as well as azide ion as nucleophiles to give the corresponding β-amino alcohols and β-azido alcohols in moderate to good yields.

scholarly journals An efficient and atom-economical route to N-aryl amino alcohols from primary amines

RSC Advances ◽  
2018 ◽  
Vol 8 (60) ◽  
pp. 34304-34308 ◽  
Author(s):  
Zhen Xiao ◽  
Juanjuan Li ◽  
Qiang Yue ◽  
Qian Zhang ◽  
Dong Li
Keyword(s):  
Ring Opening ◽  
Amino Alcohols ◽  
Primary Amines ◽  
Ring Opening Reaction ◽  
Novel Method

A novel method for generation of N-aryl amino alcohols from N,N-disubstituted picolinamides through reduction/ring-opening reaction with NaBH4 was developed.

Highly regioselective ring-opening of epoxides with amines: a metal- and solvent-free protocol for the synthesis of β-amino alcohols

2020 ◽  
Vol 56 (15) ◽  
pp. 2256-2259
Author(s):  
Dong Li ◽  
Jing Wang ◽  
Shibo Yu ◽  
Silei Ye ◽  
Wenjie Zou ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Ring Opening ◽  
Amino Alcohols ◽  
Solvent Free ◽  
Ring Opening Reaction ◽  
Ring Opening Of Epoxides

We herein report a metal- and solvent-free acetic acid-mediated ring-opening reaction of epoxides with amines.

Regio- and Stereoselective Ring-Opening Reaction of Chiral Aziridines: A Facile Synthesis of Chiral β-Amino Alcohols

Heterocycles ◽  
2009 ◽  
Vol 78 (2) ◽  
pp. 471 ◽  
Author(s):  
Kimio Higashiyama ◽  
Masataka Matsumura ◽  
Hiroshi Kojima ◽  
Takayasu Yamauchi
Keyword(s):  
Ring Opening ◽  
Amino Alcohols ◽  
Facile Synthesis ◽  
Ring Opening Reaction

ChemInform Abstract: Synthesis of β-Amino Alcohols Using the Tandem Reduction and Ring-Opening Reaction of Nitroarenes and Epoxides.

ChemInform ◽  
2016 ◽  
Vol 47 (43) ◽  
Author(s):  
Chongyang Shi ◽  
Cheng Ren ◽  
Erlei Zhang ◽  
Huile Jin ◽  
Xiaochun Yu ◽  
...  
Keyword(s):  
Ring Opening ◽  
Amino Alcohols ◽  
Ring Opening Reaction
Sign in / Sign up

Export Citation Format

Share Document