Prospective validation of an automatic reflex test for identifying spurious elevations of mean corpuscular haemoglobin concentration due to the presence of cold agglutinins

2021 ◽  
pp. 1-3
Author(s):  
Felicia Stefania Falvella ◽  
Mariia Chibireva ◽  
Mauro Panteghini
Keyword(s):  
Haemoglobin Concentration ◽  
Cold Agglutinins ◽  
Corpuscular Haemoglobin ◽  
Mean Corpuscular Haemoglobin Concentration ◽  
Mean Corpuscular Haemoglobin ◽  
Corpuscular Haemoglobin Concentration

scholarly journals Values of Selected Haematological Indicators in Six Species of Feathered Game

2010 ◽  
Vol 79 (9) ◽  
pp. S3-S8 ◽  
Author(s):  
Eva Straková ◽  
Pavel Suchý ◽  
Romana Kábelová ◽  
František Vitula ◽  
Ivan Herzig
Keyword(s):  
Blood Cell ◽  
Total Concentration ◽  
Haemoglobin Concentration ◽  
Individual Species ◽  
Neutrophil Granulocytes ◽  
Corpuscular Haemoglobin ◽  
Mean Corpuscular Haemoglobin Concentration ◽  
Mean Corpuscular Haemoglobin ◽  
The Mean ◽  
Corpuscular Haemoglobin Concentration

The present paper extends the knowledge of selected blood indicators in six species of feathered game such as helmeted guineafowl (Numida meleagris), common pheasant (Phasianus colchicus), Japanese quail (Coturnix coturnix japonica), chukar (Alectoris chucar), grey partridge (Perdix perdix) and wild turkey (Meleagris gallopavo), reared in the Czech Republic and Europe. The red blood cell (RBC) values in individual species of feathered game ranged as follows: the mean RBC counts varied in a range of 2.10 - 2.58 T/l; haematocrit values were in a range of 0.33 - 0.39 1/1; haemoglobin concentration varied in a range of 101.20 - 129.13 g/l; mean corpuscular haemoglobin concentration (MCHC) ranged from 28.63 to 35.44%; mean corpuscular haemoglobin (MCH) varied in a range of 46.15 - 62.07 pg and the mean corpuscular volume (MCV) was 147.66 - 178.20 fl. Except for the total concentration of haemoglobin and the mean corpuscular haemoglobin concentration, no significant differences were found between the mean values of RBC values in individual species of feathered game. However, some differences between species were found in white blood cell (WBC) values, ranging as follows: the total WBC count ranged from 13.55 to 26.90 G/l, basophil granulocytes from 0.011 to 0.110 G/l, eosinophil granulocytes from 0.011 to 0.593 G/l, neutrophil granulocytes from 1.868 to 6.661 G/l, lymphocytes from 10.937 to 20.922 G/l and monocytes from 0.034 to 0.199 G/l. Most values showed significant (P ⪬ 0.05) to highly significant (P ⪬ 0.01) interspecies differences. The main goal of the study was to investigate selected haematological indicators in six major species of feathered game.

scholarly journals Stability of haematological parameters in stored blood samples of rainbow trout Oncorhynchus mykiss (Walbaum, 1792)

2017 ◽  
Vol 62 (No. 7) ◽  
pp. 401-405 ◽  
Author(s):  
F. Fazio ◽  
V. Ferrantelli ◽  
C. Saoca ◽  
G. Giangrosso ◽  
G. Piccione
Keyword(s):  
Rainbow Trout ◽  
Blood Cells ◽  
Storage Time ◽  
Haemoglobin Concentration ◽  
Corpuscular Haemoglobin ◽  
Thrombocyte Count ◽  
Rainbow Trout Oncorhynchus Mykiss ◽  
Mean Corpuscular Haemoglobin Concentration ◽  
Mean Corpuscular Haemoglobin ◽  
Corpuscular Haemoglobin Concentration

The aim of this study was to investigate the influence of storage time at +4 °C on haematological indicators in rainbow trout Oncorhynchus mykiss (Walbaum, 1792). For this purpose, 60 Italian trout were evaluated and red blood cells, white blood cells, thrombocyte count, haematocrit, haemoglobin concentration, mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration were determined. After blood collection (T<sub>0</sub>), all samples were immediately analysed using an automatic method to assess the haematological parameters and then divided into two different aliquots and stored at +4 °C. The first aliquot was refrigerated for 168 h (T<sub>1</sub>), the second one for 336 h (T<sub>2</sub>). Statistical analysis (one-way repeated-measures ANOVA) showed a significant effect of storage time (P &lt; 0.05) on red blood cells, thrombocyte count, haematocrit, haemoglobin concentration, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration. The obtained data expand our knowledge of haematological evaluation techniques and could contribute to the development of an appropriate method for haematological analysis that is suitable for the evaluation of the health status of wild and farmed fish.

scholarly journals Studies on some paraclinical indices on intoxication in horses from freshly cut Jimson weed (Datura stramonium)-contaminated maize intended for ensiling : clinical communication

2006 ◽  
Vol 77 (3) ◽  
Author(s):  
R. Binev ◽  
I. Valchev ◽  
J. Nikolov
Keyword(s):  
Mean Corpuscular Volume ◽  
Haemoglobin Concentration ◽  
Datura Stramonium ◽  
Corpuscular Haemoglobin ◽  
Jimson Weed ◽  
Cell Counts ◽  
Mean Corpuscular Haemoglobin Concentration ◽  
Erythrocyte Sedimentation ◽  
Mean Corpuscular Haemoglobin ◽  
Corpuscular Haemoglobin Concentration

Monitoring of changes in some blood laboratory parameters in 34 horses after ingesting freshly harvested maize that was to be used for ensiling, heavily contaminated with young Datura stramonium plants, is described. For a 7-day period the following parameters were monitored: haemoglobin content (HGB), red blood cell counts (RBC), white blood cell counts (WBC), haematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), differential white cell counts (DWC), erythrocyte sedimentation rate (ESR), protein fractions, aspartate aminotransferase (AST), lactate dehydrogenase (LDH), total bilirubin (TB), direct bilirubin (DB), blood glucose (Glu), total protein (TP), globulin (Glob) and albumin (Alb). The intoxication was accompanied by erythrocytosis, leukocytosis, regenerative left shift neutrophilia, lymphopaenia, eosinopaenia, increased haematocrit values, low erythrocyte sedimentation rate, hyperglycaemia, bilirubinaemia, hypoproteinaemia and increased activity of AST and LDH. No changes occurred in the mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), albumin, globulin and globulin fractions (a1, a2, b1, b2 and g). The blood parameters returned to normal between post-intoxication days 2 and 5. The observed changes in clinical chemistry indices could be used in the diagnosis, differential diagnosis and prognosis of Jimson weed intoxication.

scholarly journals Physiological values of some blood indicators in selected dwarf rabbit breeds

2017 ◽  
Vol 25 (1) ◽  
pp. 27 ◽  
Author(s):  
V. Šimek ◽  
D. Zapletal ◽  
E. Straková ◽  
A. Pavlík ◽  
P. Suchý
Keyword(s):  
White Blood Cells ◽  
Haemoglobin Concentration ◽  
Live Weight ◽  
Inorganic Phosphorus ◽  
Corpuscular Haemoglobin ◽  
Mean Corpuscular Haemoglobin Concentration ◽  
Red Blood Cell Count ◽  
Mean Corpuscular Haemoglobin ◽  
Physiological Values ◽  
Corpuscular Haemoglobin Concentration

<p>The aim of the present study was to evaluate the effect of breed on haematological and biochemical indicators in 3 dwarf rabbit breeds. In the experiment, 30 sexually intact dwarf rabbit females aged 6 mo were used. With the sole exception of white blood cells and haematocrit value, breed had the most significant effect on the majority of haematological indicators monitored. The red blood cell count was higher in the Dwarf Lop compared to the Netherland Dwarf (+1.91×10<sup>12</sup> cells/L; P&lt;0.05) and also the Teddy Dwarf (+1.32×10<sup>12</sup> cells/L; P&lt;0.05). For haemoglobin concentration, a higher value was found in the Netherland Dwarf than in the Teddy Dwarf (+39.29 g/L; P&lt;0.05) and the Dwarf Lop (+26.36 g/L; P&lt;0.05). For erythrocytic indicators, the highest values of mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration were found in the Netherland Dwarf. The breed had a significant effect on the urea and potassium values. A higher value of urea was recorded in the Dwarf Lop compared to the Teddy Dwarf (+1.56 mmol/L; P&lt;0.05). For potassium, a higher value was found in the Netherland Dwarf compared to the Teddy Dwarf (+0.85 mmol/L; P&lt;0.05). In addition, a significantly positive correlation (P&lt;0.05) was found between the live weight of dwarf females and values of haematocrit (0.49), albumin (0.54), alanine aminotransferase (0.51), and aspartate aminotransferase (0.41), while a significantly negative correlation (P&lt;0.05) was found between their live weight and values of triacylglycerols (–0.44), alkaline phosphatase (–0.38) and inorganic phosphorus (–0.52). </p>

A successful modification of ultrafiltration for cardiopulmonary bypass in children

Perfusion ◽  
1991 ◽  
Vol 6 (1) ◽  
pp. 41-50 ◽  
Author(s):  
SK Naik ◽  
A. Knight ◽  
MJ Elliott
Keyword(s):  
Cardiopulmonary Bypass ◽  
Mean Corpuscular Volume ◽  
Heart Defects ◽  
Haemoglobin Concentration ◽  
Corpuscular Volume ◽  
Corpuscular Haemoglobin ◽  
Modified Method ◽  
Mean Corpuscular Haemoglobin Concentration ◽  
Mean Corpuscular Haemoglobin ◽  
Corpuscular Haemoglobin Concentration

Total body water (TBW) is increased after cardiopulmonary bypass (CPB) resulting in tissue oedema and organ dysfunction. Ultrafiltration has been used to reduce this accumulation of water, although conventional ultrafiltration seemed ineffective in reducing the rise in TBW after CPB in our clinical experience. We describe a modified technique in which ultrafiltration is performed in the first 10 minutes after the patient is weaned from bypass, returning nearly all the blood in the circuit to the patient and elevating the haematocrit (Hct) to any predetermined level. We carried out a pilot study on 21 children aged 4-144 months undergoing open-heart surgery and CPB for congenital heart defects. They were divided into three comparable groups: (1) controls (n = 6); (2) conventional ultrafiltration (n = 7); and (3) modified ultrafiltration (n = 8). TBW (bio-impedance), Hct, osmolality, mean corpuscular volume and mean corpuscular haemoglobin concentration were recorded at frequent intervals. Control patients showed elevation of TBW by 18.2% median (range 14.5-20.3), conventional ultrafiltration by 12.4% (7.9-15.0), modified ultrafiltration by 5.7% (4.5-7.1) (p < 0.0001 compared to controls, p < 0.005 compared to conventional ultrafiltration, Mann-Whitney U test). Hct could be elevated to preoperative levels only by the modified method. Mean corpuscular volume, and mean corpuscular haemoglobin concentration osmolality were unaltered. Ultrafiltration by the modified method was more effective than conventional ultrafiltration in reducing the rise in TBW and elevating Hct after CPB.

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