scholarly journals Possible regulation of genes associated with intracellular signaling cascade in rat liver regeneration

2009 ◽  
Vol 44 (4) ◽  
pp. 462-470 ◽  
Author(s):  
Cun-Shuan Xu ◽  
Heng-Yi Shao ◽  
Shuai-Shuai Liu ◽  
Bo Qin ◽  
Xiu-Feng Sun ◽  
...  
FACE ◽  
2021 ◽  
pp. 273250162110243
Author(s):  
Mikhail Pakvasa ◽  
Andrew B. Tucker ◽  
Timothy Shen ◽  
Tong-Chuan He ◽  
Russell R. Reid

Hedgehog signaling was discovered more than 40 years ago in experiments demonstrating that it is a fundamental mediator of limb development. Since that time, it has been shown to be important in development, homeostasis, and disease. The hedgehog pathway proceeds through a pathway highly conserved throughout animals beginning with the extracellular diffusion of hedgehog ligands, proceeding through an intracellular signaling cascade, and ending with the activation of specific target genes. A vast amount of research has been done elucidating hedgehog signaling mechanisms and regulation. This research has found a complex system of genetics and signaling that helps determine how organisms develop and function. This review provides an overview of what is known about hedgehog genetics and signaling, followed by an in-depth discussion of the role of hedgehog signaling in craniofacial development and carcinogenesis.


Hepatology ◽  
1995 ◽  
Vol 21 (5) ◽  
pp. 1450-1454 ◽  
Author(s):  
Gianluigi Vendemiale ◽  
Ferruccio Guerrieri ◽  
Ignazio Grattagliano ◽  
Domenico Didonna ◽  
Leonilde Muolo ◽  
...  

IUBMB Life ◽  
1999 ◽  
Vol 47 (6) ◽  
pp. 1049-1059 ◽  
Author(s):  
Maria-Letizia Tomassoni ◽  
Elisabetta Albi ◽  
Mariapia Viola Magani

The Lancet ◽  
1989 ◽  
Vol 334 (8674) ◽  
pp. 1248-1249 ◽  
Author(s):  
A Francavilla ◽  
S Todo ◽  
K.A Porter ◽  
M Barone ◽  
Q Zeng ◽  
...  

2015 ◽  
Vol 14 (3) ◽  
pp. 7643-7654 ◽  
Author(s):  
C.F. Chang ◽  
W.M. Zhao ◽  
J.X. Mei ◽  
Y. Zhou ◽  
C.Y. Pan ◽  
...  

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