Whole Body Counting of Vitamin B12 58Co Absorption Supplemented by Profile Scanning

1970 ◽  
Vol 5 (4) ◽  
pp. 261-264
Author(s):  
N. D. C. Finlayson ◽  
J. D. Simpson ◽  
D. J. C. Shearman
Keyword(s):  
Vitamin B12 ◽  
Whole Body ◽  
Body Counting ◽  
Whole Body Counting

scholarly journals Measurement of Absorption of Vitamin B12 by Whole-Body Gamma Spectrometry

Blood ◽  
1961 ◽  
Vol 18 (1) ◽  
pp. 95-101 ◽  
Author(s):  
P. G. REIZENSTEIN ◽  
EUGENE P. CRONKITE ◽  
S. H. COHN
Keyword(s):  
Vitamin B12 ◽  
Intrinsic Factor ◽  
The Body ◽  
Whole Body ◽  
Radiochemical Analysis ◽  
Body Counting ◽  
Simple Measurement ◽  
Primary Advantage ◽  
Whole Body Counting ◽  
High Degree

Abstract A technic is described to measure directly the intestinal absorption of radiovitamin B12 by using a whole-body gamma spectrometer. A double tracer technic is used, and the amounts of free and intrinsic factor bound vitamin B12, respectively, retained in the body after final excretion of unabsorbed radioactivity, are measured. The results are in agreement with those previously obtained by other methods. The present method is simple and quantitative. The primary advantage of the whole-body counter for measuring absorption of Cobalt-labeled B12 is that it can measure less than 0.1 µc. with a high degree of accuracy. Whole-body counting substitutes a rapid and simple measurement for the difficult and tedious collection and radiochemical analysis of excreta.

The Measurement of Gastro-Intestinal Absorption of Co58-Labelled Vitamin B12 by Whole Body Counting

1963 ◽  
Vol 03 (04) ◽  
pp. 349-355
Author(s):  
Barbara Anderson ◽  
C. J. Robinson ◽  
E. H. Belcher
Keyword(s):  
Vitamin B12 ◽  
Intestinal Absorption ◽  
Scintillation Counter ◽  
Whole Body ◽  
Counting Method ◽  
Recovery Method ◽  
Body Counting ◽  
Vitamin B12 Absorption ◽  
Whole Body Counting ◽  
Method Show

SummaryA method for the measurement of gastro-intestinal absorption of Co58-labelled vitamin B12 by whole body counting is described. Subjects receiving doses of 1 μg of vitamin containing 0.5—1 μc of Co58 are measured by means of a single scintillation counter detector installed in a low background enclosure, using a “standard chair” technique. Measurements on 40 patients studied both by the faecal recovery method and by the whole body counting method show that the latter provides a simple and reliable test of vitamin B12 absorption avoiding the inconvenience and uncertainty of collection of faeces or urine.

Whole-Body Counting Studies of Retention and Accessibility of Radioactive Vitamin B12

1968 ◽  
Vol 21 (6) ◽  
pp. 665-672 ◽  
Author(s):  
LEWIS M. SCHIFFER ◽  
STANTON H. COHN ◽  
DAVID C. PRICE ◽  
EUGENE P. CRONKITE
Keyword(s):  
Vitamin B12 ◽  
Whole Body ◽  
Body Counting ◽  
Whole Body Counting

Studies of Calcium Absorption in Man Using a CD-2 Whole-Body Counter

1977 ◽  
Vol 16 (04) ◽  
pp. 163-167
Author(s):  
K. Bakos ◽  
Věra Wernischová
Keyword(s):  
Calcium Absorption ◽  
Whole Body ◽  
Control Group ◽  
Absorption Process ◽  
Whole Body Counter ◽  
Absorption Studies ◽  
Body Counting ◽  
Calcium Load ◽  
Calcium Malabsorption ◽  
Whole Body Counting

SummaryWhole-body counting makes an important contribution of radioisotope techniques to ȁEin vivo“ absorption studies, in comparison with other methods. In a large number of subjects, the method was tested for its usefulness in the diagnosis of calcium malabsorption. The effects of drugs, of the calcium load in the gut and of the whole-body content of calcium on the absorption process were studied in a control group.

A Modified Chair Geometry for Whole Body Counting

1976 ◽  
Vol 15 (05) ◽  
pp. 246-247
Author(s):  
S. C. Jain ◽  
G. C. Bhola ◽  
A. Nagaratnam ◽  
M. M. Gupta
Keyword(s):  
Marked Improvement ◽  
Point Of View ◽  
Whole Body ◽  
Spatial Response ◽  
Body Counting ◽  
The Subject ◽  
Whole Body Counting ◽  
The Buddha

SummaryIn the Marinelli chair, a geometry widely used in whole body counting, the lower part of the leg is seen quite inefficiently by the detector. The present paper describes an attempt to modify the standard chair geometry to minimise this limitation. The subject sits crossed-legged in the “Buddha Posture” in the standard chair. Studies with humanoid phantoms and a volunteer sitting in the Buddha posture show that this modification brings marked improvement over the Marinelli chair both from the point of view of sensitivity and uniformity of spatial response.

Body potassium by four-pi 40K counting: an anthropometric correction

1984 ◽  
Vol 246 (2) ◽  
pp. F234-F239 ◽  
Author(s):  
R. N. Pierson ◽  
J. Wang ◽  
J. C. Thornton ◽  
T. B. Van Itallie ◽  
E. W. Colt
Keyword(s):  
Adipose Tissue ◽  
Single Crystal ◽  
Covariance Analysis ◽  
Whole Body ◽  
Exchangeable Sodium ◽  
Independent Evidence ◽  
Body Counting ◽  
Whole Body Counting

Four-pi whole body counting for the 1.46 meV photon of 40K has apparent advantages over single-crystal or two-pi counters in efficiency and in subject geometry independence. However, our studies of obese populations have disclosed a systematic undermeasurement of 40K, suggesting that nonhomogeneous K distribution results in systematic undercounting of 40K. In the current study 42K, emitting a 1.52 meV photon, was used in 109 volunteers ranging from 50 to 181 kg, and multiregression covariance analysis was applied to develop correction formulas based on anthropometrics. These corrections quantitatively account for the unappreciated loss of 40K and 42K photons in annular adipose tissue that surrounds the lean body, in which most K+ is concentrated. The correction ranges from 1 to 28% and is a linear (although different) function of weight in both sexes. Thus corrected, body potassium measurements, taken in conjunction with exchangeable sodium and water measurements, provide estimates for whole body osmolality that match measured serum values. Such a quantitative accounting for previously "lost" cation in 58 subjects provides independent evidence for the appropriateness and accuracy of the correction. With this correction, body potassium was recalculated in the 1,492 adult members of a previously reported group of 3,083 subjects.

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