Feasibility of transient elastography versus real-time two-dimensional shear wave elastography in difficult-to-scan patients

2016 ◽  
Vol 51 (11) ◽  
pp. 1354-1359 ◽  
Author(s):  
Benjamin Staugaard ◽  
Peer Brehm Christensen ◽  
Belinda Mössner ◽  
Janne Fuglsang Hansen ◽  
Bjørn Stæhr Madsen ◽  
...  
2021 ◽  
Vol 62 (1) ◽  
pp. 34-43
Author(s):  
Danijela Zjačić Puljiz ◽  
Ivana Kristina Delić Jukić ◽  
Marko Puljiz ◽  
Lučana Vicelić Čutura ◽  
Iva Jerčić Martinić-Cezar ◽  
...  

2021 ◽  
Author(s):  
Jiajia Wang ◽  
Minxia Hu ◽  
Qiang Zhu ◽  
Lanting Sun

Abstract Background To explore the value of liver stiffness assessed by two-dimensional real-time shear wave elastography (2D-SWE)in predicting the occurrence of hypersplenism in patients diagnosed with Wilson’s disease (WD). Methods A total of 90 WD patients were enrolled in this prospective study between May 2018 and December 2018. Clinical data and ultrasound imaging including 2D-SWE liver stiffness of WD patients as baseline data were collected. Patients were followed up for 24 months, or patients developed hypersplenism after enrollment. Risk factors for hypersplenism were determined using cox regression and receiver operating characteristic curve. Results Twenty-night (32.2%) patients were found developed hypersplenism. The age, the diameter of portal vein, and the liver stiffness were independent risk factors associated with hypersplenism in WD. The cutoff value of liver stiffness for predicting hypersplenism was 10.45 kPa, with sensitivity and specificity of 75.9% and 73.8%, respectively. When patients were divided into two groups according to liver stiffness ≥10.45 kPa or <10.45 kPa, the incidence of hypersplenism were 57.9% vs. 13.5% (P<0.001), and the median time between the enrollment and the development of hypersplenism was 15 months vs. 22 months (P<0.001) for the two groups, respectively. Conclusion The liver stiffness measured by 2D-SWE was a reliable predictor of hypersplenism in WD patients. Dynamic monitoring WD patients using 2D-SWE is crucial for the early diagnosis of hypersplenism.


2021 ◽  
Vol 25 (3) ◽  
pp. 166-170
Author(s):  
Roberta Indriulytė ◽  
Diana Leškytė ◽  
Algidas Basevičius

Tyrimo tikslas. Įvertinti neinvazinius tyrimus kaip alternatyvą biopsijai, nustatant kepenų fibrozę ir vertinant atsaką į gydymą. Tyrimo metodai. Nuo 2020 m. gruodžio mėn. iki 2021 m. vasario mėn. atrinktos mokslinės publikacijos iš „PubMed“ duomenų bazės pagal reikšminius žodžius, remiantis įtraukimo ir neįtraukimo į tyrimą kriterijais. Rezultatai. Magnetinio rezonanso elastografija (MRE) yra jautresnė vertinant kepenų fibrozę ir cirozę nei magnetinio rezonanso tyrimas (MRT). MRE, neinvazinė vibracijos kontroliuojama trumpalaikė elastografija (angl. vibration-controlled transient elastography (VCTE)) ir 2D skersinės bangos elastografija (angl. 2D shear wave elastography (2D-SWE)) tikslūs diagnozuojant kepenų fibrozę pacientams, sergantiems nealkoholiniu kepenų suriebėjimu. Realaus laiko elastografija (angl. real time elastography (RTE)) leidžia nustatyti pažengusią fibrozę, o VCTE tiksliai nustato tiek ankstyvą, tiek pažengusią fibrozę. Kompiuterinės tomografijos (KT) tyrimas yra gana reikšmingas kepenų fibrozei diagnozuoti ir gydymo atsakui įvertinti. Išvados. Šie neinvaziniai tyrimai gali būti kaip alternatyva plačiai taikomai kepenų biopsijai.


2018 ◽  
Vol 20 (2) ◽  
pp. 127 ◽  
Author(s):  
Yeun-Yoon Kim ◽  
Myung-Joon Kim ◽  
Hyun Joo Shin ◽  
Haesung Yoon ◽  
Ha Yan Kim ◽  
...  

Aims: To enable comparison and interconversion of elasticity measurements between two-dimensional (2D) shear wave elastography (SWE) and transient elastography (TE).Materials and methods: Elasticities of three phantoms were measured by 2D SWE (supersonic shear imaging) using four probes and TE using two probes. We performed regression analyses to evaluate correlation between the measurements and phantom elasticities, and make converting equations. In pediatric biliary atresia patients who had stiffness measurements by both 2D SWE and TE within 1-year interval, TE measurements were retrospectively converted into correlating 2D SWE values. We compared the calculated values with 2D SWE measurements by intraclass correlation coefficient.Results: Measurements in phantoms varied according to elastography method and probe selection. However, the measurement by both 2D SWE (R2, 0.974-0.985; p<0.001) and TE (R2, 0.996-0.999; p<0.001) showedsignificant linear correlation with phantom elasticity in all probe settings. From 67 biliary atresia patients (age, 2 months-20 years), agreements between the measured and calculated values were excellent in all 88 examinations within 1-year interval(ρ=0.828; p<0.001) and in 63 examinations within 2-month interval (ρ=0.863, p<0.001). Conclusions: The equations enabledinterconversion of elasticity values among different probes of 2D SWE and TE and provided reliable estimation of elasticityvalues for different probe settings in biliary atresia patients.


2019 ◽  
Vol 10 (9) ◽  
pp. 1975-1984
Author(s):  
Rui-Jun Han ◽  
Jing Du ◽  
Feng-Hua Li ◽  
Hao-Ru Zong ◽  
Jia-Dong Wang ◽  
...  

Author(s):  
Danijela Zjacic Puljiz ◽  
Antonio Mestrovic ◽  
Ivan Zaja ◽  
Ante Tonkic ◽  
Ivica Grgurevic ◽  
...  

2020 ◽  
Vol 22 (4) ◽  
pp. 192-195
Author(s):  
I. I. Zhirkov ◽  
A. V. Gordienko ◽  
I. M. Pavlovich ◽  
V. V. Yakovlev ◽  
D. Yu. Serdyukov

The presents modern information about a non-invasive instrumental technique for assessing fibrotic changes in the liver elastography. The data on the history of the origin of the term elastography are presented, several of its definitions are given, and attention is also paid to the main principle of the technique percussion, which is traditionally used in an objective study of a patient. The facts about the dual terminology of the technique in the literature are presented, in which some authors use the term elastography, and the other part elastometry. When analyzing the literature, it turned out that in foreign sources the term elastography is much more often used, and both names of the method are used in Russian. Given the greater prevalence of the elastography option, it is more logical to use it, but each of these names has its own right to exist. Definitions are given for the basic physical concepts associated with the elastography method elasticity, rigidity and Youngs modulus of elasticity. From the point of view of application in clinical practice, elastography techniques can be divided into four groups: compression elastography, which is more often used in oncodiagnostics, transient, point and two-dimensional shear wave elastography, used in the diagnosis of liver fibrosis. Physical classification involves dividing elastography into two types: static, which includes compression elastography, and dynamic, which includes transient, point and two-dimensional shear wave elastography. Transient elastography is implemented in devices of the FibroScan family, point elastography in ultrasound scanners from Hitachi Aloka, Siemens and Philips, two-dimensional shear wave elastography in devices from Supersonic Imagine, Toshiba, Siemens, Mindray, General Electric. The widest range of possibilities for assessing liver fibrosis is provided by two-dimensional shear wave elastography. The combined use of several techniques is expected to increase the diagnostic accuracy in determining fibrosis. Magnetic resonance elastography has the greatest accuracy among elastographic techniques, but its application is limited due to the complexity and high cost of equipment, therefore, this technique has not yet found wide application in clinical practice.


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