Acute acalculous cholecystitis: A rare presentation of typhoid fever in adults

2006 ◽  
Vol 38 (3) ◽  
pp. 196-200 ◽  
Author(s):  
Chung-Hsu Lai ◽  
Chun-Kai Huang ◽  
Chuen Chin ◽  
Hsi-Hsun Lin ◽  
Chih-Yu Chi ◽  
...  
2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Zuhal Yesilbag ◽  
Asli Karadeniz ◽  
Fatih Oner Kaya

Primary Epstein-Barr virus (EBV) infection is almost always a self-limited disease characterized by sore throat, fever, and lymphadenopathy. Hepatic involvement is usually characterized by mild elevations of aminotransferases and resolves spontaneously. Although isolated gallbladder wall thickness has been reported in these patients, acute acalculous cholecystitis is an atypical presentation of primary EBV infection. We presented a young women admitted with a 10-day history of fever, nausea, malaise who had jaundice and right upper quadrant tenderness on the physical examination. Based on diagnostic laboratory tests and abdominal ultrasonographic findings, cholestasis and acute acalculous cholecystitis were diagnosed. Serology performed for EBV revealed the acute EBV infection. Symptoms and clinical course gradually improved with the conservative therapy, and at the 1-month follow-up laboratory findings were normal. We reviewed 16 adult cases with EBV-associated AAC in the literature. Classic symptoms of EBV infection were not predominant and all cases experienced gastrointestinal symptoms. Only one patient underwent surgery and all other patients recovered with conservative therapy. The development of AAC should be kept in mind in patients with cholestatic hepatitis due to EBV infection to avoid unnecessary surgical therapy and overuse of antibiotics.


2021 ◽  
Vol 8 ◽  
Author(s):  
Yuehua Gong ◽  
Jianlin Li ◽  
Dongnan Zhu ◽  
Songsong Wang ◽  
Yingchun Xu ◽  
...  

Typhoid fever is usually a mild clinical disease. Typhoid fever with massive intestinal hemorrhage is rare in the antibiotic era. Acute acalculous cholecystitis (AAC) is also rare in adults. Here, we describe the first adult case of typhoid fever with both complications due to Vi-negative and fluoroquinolone-insensitive Salmonella enterica serovar Typhi (S. Typhi) infection. We aim to alert physicians to this rare condition.


Author(s):  
Maymona Choudry ◽  

Typhoid fever is one of the most common enteric fever in low to middle income countries. In the pediatric population, it is a rare cause of acalculous cholecystitis in which one of the dreaded complication is gall bladder perforation. This was a case of a 15-year-old male with 1-month history of intermittent undocumented fever, anorexia and weight loss. The patient presented with signs of pancytopenia and abdominal examination revealed acute abdomen. Patient was optimized and prepared for surgery. Intraoperative findings revealed Type II gall bladder perforation with bile peritonitis, and patient underwent exploratory laparotomy, cholecystectomy, lavage, Jackson-Pratt drain. The sepsis eventually resolved postoperatively, and the patient was discharged. Preoperative diagnosis in patients with gall bladder perforation is often challenging and sophisticated, due to its rarity. However, it should be considered as one of the differential diagnoses in pediatric patients presenting with atypical history of abdominal pain. At present, there are no specific guidelines in the management of complications such as gall bladder perforation in patients with typhoid fever. Therefore, early diagnosis and immediate surgical intervention of gall bladder perforation are of prime importance in the successful outcomes of these patients, given the high morbidity and mortality associated with this condition.


2013 ◽  
Vol 5 (2) ◽  
pp. 140-142
Author(s):  
Deepak Madi ◽  
Basavaprabhu Achappa ◽  
John T Ramapuram ◽  
Nithyananda Chowta ◽  
Mridula Laxman ◽  
...  

The classical presentation of typhoid has changed over the years. Atypical presentation of typhoid is now seen in clinical practice. Entericfever can present with atypical manifestations like abdominal lymphadenopathy, acute acalculous cholecystitis, osteomyelitis, splenic abscess and Pneumonia. Jaundice splenic abscess and thrombocytopenia in a febrile patient in the tropics is commonly due to Malaria, Leptospirosis and Dengue. We report a case of typhoid fever presenting with jaundice and thrombocytopenia. A 17 year old male presented to us with history of fever and jaundice. Investigations revealed thrombocytopenia and conjugated hyperbilirubinemia. Blood culture grew Salmonella Typhi. He was treated with ceftriaxone and he improved. A diagnosis of typhoid fever must be considered in a febrile patient with jaundice and thrombocytopenia in the tropics. DOI: http://dx.doi.org/10.3126/ajms.v5i2.8584   Asian Journal of Medical Science, Volume-5(2) 2014: 140-142


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Neeha Rajan ◽  
Imeldah Motoroko ◽  
Dilshan Udayasiri ◽  
Jo-Lyn McKenzie ◽  
Jason S. C. Tan ◽  
...  

Introduction. Acalculous cholecystitis in the setting of typhoid fever in adults is an infrequent clinical encounter, reported sparsely in the literature. In this case report we review the presentation and management of enteric fever involving the biliary system and consider the literature surrounding this topic. The aim of this case report is to alert clinicians to the potential diagnosis of extraintestinal complications in the setting of typhoid fever in the returned traveller, requiring surgical intervention.Presentation of Case. We report the case of a 23-year-old woman with acalculous cholecystitis secondary toSalmonellaTyphi.Discussion. There is scarce evidence surrounding the optimal treatment and prognosis of typhoidal acalculous cholecystitis. In the current case, surgical invention was favoured due to failure of medical management.Conclusion. Clinical judgement dictated surgical intervention in this case of typhoidal acute acalculous cholecystitis, and cholecystectomy was safely performed.


2021 ◽  
Vol 13 (1) ◽  
pp. 86-90
Author(s):  
Carlos Leganés Villanueva ◽  
Ilaria Goruppi ◽  
Nuria Brun Lozano ◽  
Federica Bianchi ◽  
María Quinteiro González ◽  
...  

Epstein–Barr virus (EBV) is estimated to infect more than 98% of adults worldwide and is one of the most common human viruses. Acute acalculous cholecystitis (AAC) of the gallbladder is an atypical complication of infectious mononucleosis caused by EBV. Conservative management has been described in the context of AAC caused by EBV. A surgical approach must be considered in the case of acute complications such as perforation or gallbladder gangrene. We present the case of a 10-year-old female patient with AAC due to infectious mononucleosis syndrome caused by primary EBV infection.


Sign in / Sign up

Export Citation Format

Share Document