scholarly journals Case Report: Near-Fatal Intestinal Hemorrhage and Acute Acalculous Cholecystitis due to Vi-Negative and Fluoroquinolone-Insensitive Salmonella enterica Serovar Typhi Infection: A Rare Entity

2021 ◽  
Vol 8 ◽  
Author(s):  
Yuehua Gong ◽  
Jianlin Li ◽  
Dongnan Zhu ◽  
Songsong Wang ◽  
Yingchun Xu ◽  
...  
Keyword(s):  
Case Report ◽  
Typhoid Fever ◽  
Salmonella Enterica ◽  
Rare Condition ◽  
Acalculous Cholecystitis ◽  
Acute Acalculous Cholecystitis ◽  
Rare Entity ◽  
Adult Case ◽  
Salmonella Enterica Serovar Typhi ◽  
Intestinal Hemorrhage

Typhoid fever is usually a mild clinical disease. Typhoid fever with massive intestinal hemorrhage is rare in the antibiotic era. Acute acalculous cholecystitis (AAC) is also rare in adults. Here, we describe the first adult case of typhoid fever with both complications due to Vi-negative and fluoroquinolone-insensitive Salmonella enterica serovar Typhi (S. Typhi) infection. We aim to alert physicians to this rare condition.

scholarly journals Typhoid Fever due to Extended Spectrum β-Lactamase-Producing Salmonella enterica Serovar Typhi: A Case Report and Literature Review

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Abdul Azeez Ahamed Riyaaz ◽  
Vindya Perera ◽  
Sabaratnam Sivakumaran ◽  
Nelun de Silva
Keyword(s):  
Case Report ◽  
Sri Lanka ◽  
Typhoid Fever ◽  
Salmonella Enterica ◽  
Salmonella Enterica Serovar Typhi ◽  
Extended Spectrum ◽  
Cephalosporin Resistance ◽  
Resistant Strains ◽  
Derivatives Of

Emergence of cephalosporin-resistant strains of Salmonella enterica serovar Typhi is a cause of concern in the management of enteric fever. Cephalosporin resistance in Salmonella species is mainly due to the production of extended-spectrum β-lactamases (ESBLs). The majority of ESBLs in Salmonella enterica serovar Typhi are derivatives of the TEM, SHV, and CTX-M β-lactamase families. Of these, CTX-M appears to be predominant. This paper discusses the detection and molecular characterization of an ESBL-producing Salmonella enterica serovar Typhi strain isolated from a patient who was admitted to a private hospital in Sri Lanka. The three main types of β-lactamases such as TEM, SHV, and CTX-M were identified in this isolate. This case report from Sri Lanka contributes to the knowledge of the increasingly reported cases of typhoid fever due to Salmonella enterica serovar Typhi resistant to β-lactamase by ESBL production.

scholarly journals A Case Report of a Typhoid Fever Outbreak with an Uncommon Vehicle and Source of Salmonella Enterica Serotype Typhi

2021 ◽  
Vol 3 (1) ◽  
pp. 1-3
Author(s):  
Douglas W Mushi ◽  
Keyword(s):  
Case Report ◽  
Typhoid Fever ◽  
Salmonella Enterica ◽  
Endemic Region ◽  
Salmonella Enterica Serovar Typhi

Two goat caretakers aged 19 and 25 years old were infected with Salmonella enterica serovar typhi (S. typhi); both had eaten raw carrots from a garden enriched with goat faeces in typhoid endemic region of Morogoro, Tanzania. S. typhi strains isolated from garden soils and carrots proved to be from goat faeces. This data provide evidence for the spread of typhoid fever through carrots contaminated by faeces from goats contained transient S. typhi.

scholarly journals A Case Report of Typhoidal Acute Acalculous Cholecystitis

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Neeha Rajan ◽  
Imeldah Motoroko ◽  
Dilshan Udayasiri ◽  
Jo-Lyn McKenzie ◽  
Jason S. C. Tan ◽  
...  
Keyword(s):  
Case Report ◽  
Typhoid Fever ◽  
Enteric Fever ◽  
Surgical Intervention ◽  
Acalculous Cholecystitis ◽  
Clinical Encounter ◽  
Clinical Judgement ◽  
Acute Acalculous Cholecystitis ◽  
Current Case ◽  
Extraintestinal Complications

Introduction. Acalculous cholecystitis in the setting of typhoid fever in adults is an infrequent clinical encounter, reported sparsely in the literature. In this case report we review the presentation and management of enteric fever involving the biliary system and consider the literature surrounding this topic. The aim of this case report is to alert clinicians to the potential diagnosis of extraintestinal complications in the setting of typhoid fever in the returned traveller, requiring surgical intervention.Presentation of Case. We report the case of a 23-year-old woman with acalculous cholecystitis secondary toSalmonellaTyphi.Discussion. There is scarce evidence surrounding the optimal treatment and prognosis of typhoidal acalculous cholecystitis. In the current case, surgical invention was favoured due to failure of medical management.Conclusion. Clinical judgement dictated surgical intervention in this case of typhoidal acute acalculous cholecystitis, and cholecystectomy was safely performed.

scholarly journals Highly Resistant Salmonella enterica Serovar Typhi with a NovelgyrAMutation Raises Questions about the Long-Term Efficacy of Older Fluoroquinolones for Treating Typhoid Fever

2012 ◽  
Vol 56 (5) ◽  
pp. 2761-2762 ◽  
Author(s):  
Kanika Deshpande Koirala ◽  
Duy Pham Thanh ◽  
Sudeep Dhoj Thapa ◽  
Amit Arjyal ◽  
Abhilasha Karkey ◽  
...  
Keyword(s):  
Multidrug Resistance ◽  
Typhoid Fever ◽  
Treatment Failure ◽  
Salmonella Enterica ◽  
Systemic Infection ◽  
Resistant Isolate ◽  
Content Type ◽  
Salmonella Enterica Serovar Typhi ◽  
Term Efficacy

ABSTRACTAs a consequence of multidrug resistance, clinicians are highly dependent on fluoroquinolones for treating the serious systemic infection typhoid fever. While reduced susceptibility to fluoroquinolones, which lessens clinical efficacy, is becoming ubiquitous, comprehensive resistance is exceptional. Here we report ofloxacin treatment failure in typhoidal patient infected with a novel, highly fluoroquinolone-resistant isolate ofSalmonella entericaserovar Typhi. The isolation of this organism has serious implications for the long-term efficacy of ciprofloxacin and ofloxacin for typhoid treatment.

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