Review: recent advances and future development of metal complexes as anticancer agents

2017 ◽  
Vol 70 (13) ◽  
pp. 2175-2201 ◽  
Author(s):  
Pengpeng Jia ◽  
Ruizhuo Ouyang ◽  
Penghui Cao ◽  
Xiao Tong ◽  
Xia Zhou ◽  
...  
Keyword(s):  
Metal Complexes ◽  
Future Development ◽  
Anticancer Agents ◽  
Recent Advances

Novel Chemotherapeutic Agents - The Contribution of Scorpionates

2020 ◽  
Vol 26 (41) ◽  
pp. 7452-7475 ◽  
Author(s):  
Marta A. Andrade ◽  
Luísa M.D.R.S. Martins
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Anticancer Agents ◽  
Medicinal Chemistry ◽  
Bioinorganic Chemistry ◽  
Chemotherapeutic Agents ◽  
Great Role ◽  
Anticancer Properties ◽  
Scorpionate Ligands

: The development of safe and effective chemotherapeutic agents is one of the uppermost priorities and challenges of medicinal chemistry and new transition metal complexes are being continuously designed and tested as anticancer agents. Scorpionate ligands have played a great role in coordination chemistry, since their discovery by Trofimenko in the late 1960s, with significant contributions in the fields of catalysis and bioinorganic chemistry. Scorpionate metal complexes have also shown interesting anticancer properties, and herein, the most recent (last decade) and relevant scorpionate complexes reported for application in medicinal chemistry as chemotherapeutic agents are reviewed. The current progress on the anticancer properties of transition metal complexes bearing homo- or hetero- scorpionate ligands, derived from bis- or tris-(pyrazol-1-yl)-borate or -methane moieties is highlighted.

Recent Advances in Development of Polyphenols as Anticancer Agents

2018 ◽  
Vol 18 (15) ◽  
pp. 1265-1269 ◽  
Author(s):  
Sreekanth Thota ◽  
Daniel Alencar Rodrigues ◽  
Eliezer J. Barreiro
Keyword(s):  
Anticancer Agents ◽  
Recent Advances

Recent Advances in the Development of Thioredoxin Reductase Inhibitors as Anticancer Agents

2012 ◽  
Vol 13 (11) ◽  
pp. 1432-1444 ◽  
Author(s):  
Yang Liu ◽  
Yijing Li ◽  
Shenghui Yu ◽  
Guisen Zhao
Keyword(s):  
Anticancer Agents ◽  
Thioredoxin Reductase ◽  
Reductase Inhibitors ◽  
Recent Advances

Carbohydrate-Metal Complexes and their Potential as Anticancer Agents

2008 ◽  
Vol 15 (25) ◽  
pp. 2574-2591 ◽  
Author(s):  
Christian Hartinger ◽  
Alexey Nazarov ◽  
Shaheen Ashraf ◽  
Paul Dyson ◽  
Bernhard Keppler
Keyword(s):  
Metal Complexes ◽  
Anticancer Agents

Recent Advances in B-RAF Inhibitors as Anticancer Agents

2022 ◽  
pp. 105597
Author(s):  
Pathan Shahebaaz Khan ◽  
Patil Rajesh ◽  
Patil Rajendra ◽  
Manohar G. Chaskar ◽  
Arote Rohidas ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Recent Advances

Recent Advances in Biological and Catalytic Activities of Schiff base containing Acetylacetone and their Metal Complexes - A Short Overview

2020 ◽  
Vol 13 (5) ◽  
pp. 395-406
Author(s):  
Raisul Islam ◽  
Ekhlass Uddin ◽  
Ashrafuzzaman ◽  
Nur Amin Bitu ◽  
Ali Asraf ◽  
...  
Keyword(s):  
Schiff Base ◽  
Metal Complexes ◽  
Catalytic Activities ◽  
Short Overview ◽  
Recent Advances

scholarly journals Hydroxylated phosphines as ligands for chalcogenide clusters: self assembly, transformations and stabilization

2017 ◽  
Vol 89 (3) ◽  
pp. 379-392 ◽  
Author(s):  
Maxim N. Sokolov ◽  
Alexander V. Anyushin ◽  
Rita Hernandez-Molina ◽  
Rosa Llusar ◽  
Manuel G. Basallote
Keyword(s):  
Transition Metal ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Self Assembly ◽  
Structure Elucidation ◽  
Alkyl Chain ◽  
Chalcogenide Clusters ◽  
Recent Advances

AbstractThis contribution is a documentation of recent advances in the chemistry of chalcogenide polynuclear transition metal complexes coordinated with mono- and di-phosphines functionalized with hydroxo groups. A survey of complexes containing tris(hydroxymethyl)phosphine (THP) is presented. The influence of the alkyl chain in bidentate phosphines, bearing the P–(CH2)x–OH arms, is also analyzed. Finally, isolation and structure elucidation of the complexes with HP(OH)2, P(OH)3, As(OH)3, PhP(OH)2, stabilized by coordination to Ni(0) and Pd(0) centers embedded into chalcogenide clusters, is discussed.

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