Compressive vertebral hemangiomas with neurological deficits: diagnosis, surgical strategies and long term outcome

2021 ◽  
pp. 1-11
Author(s):  
Krishnakumar Kesavapisharady ◽  
Ganesh Divakar ◽  
Tobin George ◽  
Jayadevan E. R. ◽  
Easwer Venkat Hariharan
Keyword(s):  
Neurological Deficits ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Surgical Strategies ◽  
Vertebral Hemangiomas

Long-Term Outcome of Surgical Management in Symptomatic Pediatric Vertebral Hemangiomas Presenting With Myelopathy

Neurosurgery ◽  
2021 ◽  
Vol 89 (Supplement_2) ◽  
pp. S51-S51
Author(s):  
Pankaj K Singh ◽  
Sarat P Chandra ◽  
Mohit Agrawal ◽  
Dattaraj Sawarkar ◽  
Rajender Kumar ◽  
...  
Keyword(s):  
Surgical Management ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Vertebral Hemangiomas

scholarly journals Cavernous Malformation of Brainstem, Thalamus, and Basal Ganglia

Neurosurgery ◽  
2012 ◽  
Vol 72 (4) ◽  
pp. 573-589 ◽  
Author(s):  
Paritosh Pandey ◽  
Erick M. Westbroek ◽  
Peter A. Gooderham ◽  
Gary K. Steinberg
Keyword(s):  
Basal Ganglia ◽  
Neurological Deficits ◽  
Term Outcome ◽  
Cavernous Malformations ◽  
Long Term Outcome ◽  
Brain Malformations ◽  
Hemorrhage Risk ◽  
Clinical Records

Abstract BACKGROUND: Cavernous malformations (CMs) in deep locations account for 9% to 35% of brain malformations and are surgically challenging. OBJECTIVE: To study the clinical features and outcomes following surgery for deep CMs and the complication of hypertrophic olivary degeneration (HOD). METHODS: Clinical records, radiological findings, operative details, and complications of 176 patients with deep CMs were reviewed retrospectively. RESULTS: Of 176 patients with 179 CMs, 136 CMs were in the brainstem, 27 in the basal ganglia, and 16 in the thalamus. Cranial nerve deficits (51.1%), hemiparesis (40.9%), numbness (34.7%), and cerebellar symptoms (38.6%) presented most commonly. Hemorrhage presented in 172 patients (70 single, 102 multiple). The annual retrospective hemorrhage rate was 5.1% (assuming CMs are congenital with uniform hemorrhage risk throughout life); the rebleed rate was 31.5%/patient per year. Surgical approach depended on the proximity of the CM to the pial or ependymal surface. Postoperatively, 121 patients (68.8%) had no new neurological deficits. Follow-up occurred in 170 patients. Delayed postoperative HOD developed in 9/134 (6.7%) patients with brainstem CMs. HOD occurred predominantly following surgery for pontine CMs (9/10 patients). Three patients with HOD had palatal myoclonus, nystagmus, and oscillopsia, whereas 1 patient each had limb tremor and hemiballismus. At follow-up, 105 patients (61.8%) improved, 44 (25.9%) were unchanged, and 19 (11.2%) worsened neurologically. Good preoperative modified Rankin Score (98.2% vs 54.5%, P = .001) and single hemorrhage (89% vs 77.3%, P < .05) were predictive of good long-term outcome. CONCLUSION: Symptomatic deep CMs can be resected with acceptable morbidity and outcomes. Good preoperative modified Rankin Score and single hemorrhage are predictors of good long-term outcome.

scholarly journals Replacement of the ascending aorta in early childhood: Surgical strategies and long-term outcome

2018 ◽  
Vol 10 (3-4) ◽  
pp. 280
Author(s):  
Anne Moreau de Bellaing ◽  
Olivier Raisky ◽  
Ayman Haydar ◽  
Damien Bonnet ◽  
Fanny Bajolle
Keyword(s):  
Early Childhood ◽  
Ascending Aorta ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Surgical Strategies

Congenitally corrected transposition of the great arteries

ESC CardioMed ◽  
2018 ◽  
pp. 837-840
Author(s):  
Robert Yates ◽  
Marietta Charakida
Keyword(s):  
Heart Block ◽  
Right Ventricular Failure ◽  
Adverse Impact ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Surgical Strategies ◽  
Congenitally Corrected Transposition ◽  
Corrected Transposition

Isolated congenitally corrected transposition of the great arteries may remain undiagnosed or cause few problems for decades. Late complete heart block and right ventricular failure with tricuspid regurgitation have an adverse impact on long-term outcome. It is much more common for congenitally corrected transposition of the great arteries to occur with major associated cardiac abnormalities, and these will determine the clinical presentation, natural history, and treatment. A number of different surgical strategies can be considered for such patients, and the best approach is not yet clear. Specialist follow-up is therefore required.

scholarly journals A Retrospective Observational Analysis on the Outcome of Microlumbar Discectomy among 70 Consecutive Cases in the Tertiary Care Spine Center in Nepal

2019 ◽  
Vol 16 (3) ◽  
pp. 34-39
Author(s):  
Binod Bhattarai ◽  
Shashi Bhushan Sah
Keyword(s):  
Wound Infection ◽  
Lumbar Disc ◽  
Tertiary Care ◽  
Lumbar Discectomy ◽  
Neurological Deficits ◽  
Disc Disease ◽  
Term Outcome ◽  
Lumbar Disc Disease ◽  
Long Term Outcome

Lumbar disc disease is a commonly encountered spine problem. There have been various modalities of treatment that have evolved over the years. The objective of our study is to analyze safety, efficacy, and complications following Micro-lumbar discectomy. All the cases admitted in our spine clinic with symptomatic lumbar disc and who underwent Micro-lumbar discectomy between February2013 to February 2018 were included in our study. Seventy cases were operated during this period. Total operative time, immediate and long term outcome with regards to pain and neurological deficits were tabulated and analyzed for each patient. Furthermore, short and long term complications including wound infection, discit is, instability and recurrence at the same level were also studied and compared with similar studies from the literature. None of our cases had complications related to wound infection, instability or post-operativediscitis. Immediate relief from the radicular pain experienced in the pre-operative period was seen in all patients (Visual analog scale) though benign tingling sensation persisted in a few of them that improved in a short span of time. Recurrence was seen in only one case. Micro-lumbar discectomy is a minimally invasive spine procedure conferring high benefits to the patients. While compared to other methods of intervention, it has a low risk of complications as well as chances of disc recurrences.

scholarly journals Long-Term Survival and Outcome in Children Admitted to Kilifi District Hospital with Convulsive Status Epilepticus

2014 ◽  
Vol 2014 ◽  
pp. 1-7
Author(s):  
Agnes Prins ◽  
Eddie Chengo ◽  
Victor Mung'ala Odera ◽  
Manish Sadarangani ◽  
Claire Seaton ◽  
...  
Keyword(s):  
Status Epilepticus ◽  
Neurological Deficits ◽  
Control Group ◽  
Convulsive Status Epilepticus ◽  
Term Outcome ◽  
Term Survival ◽  
Long Term Outcome ◽  
Neurodevelopmental Impairment ◽  
Active Epilepsy

Objectives. The incidence of convulsive status epilepticus (CSE) is high in Africa but the long-term outcome is unknown. We examined the neurocognitive outcome and survival of children treated for CSE in a Kenyan hospital 3 to 4 years after discharge. Methods. The frequency and nature of neurological deficits among this group of children were determined and compared to a control group. The children were screened with the Ten Questions Questionnaire for neurodevelopmental impairment if alive and those that screened positive were invited for further assessment to determine the pattern and extent of their impairment. A verbal autopsy was performed to determine the cause of death in those that died. Results. In the 119 cases followed-up, 9 (8%) died after discharge, with the majority having seizures during their fatal illness. The 110 survivors (median age 5 years) had significantly more neurological impairments on the screening compared to 282 controls (34/110 (30.9%) versus 11/282 (3.9%), OR = 11.0, 95% CI 5.3–22.8). Fifteen percent of the cases had active epilepsy. Conclusions. This study demonstrates the considerable burden of CSE in African children. Strategies to manage children with CSE that are acceptable to the community need to be explored to improve the longer-term outcome.

scholarly journals History before diagnosis in childhood craniopharyngioma: associations with initial presentation and long-term prognosis

2015 ◽  
Vol 173 (6) ◽  
pp. 853-862 ◽  
Author(s):  
Anika Hoffmann ◽  
Svenja Boekhoff ◽  
Ursel Gebhardt ◽  
Anthe S Sterkenburg ◽  
Anna M M Daubenbüchel ◽  
...  
Keyword(s):  
Tumor Size ◽  
Age At Diagnosis ◽  
Neurological Deficits ◽  
Term Outcome ◽  
Specific Symptom ◽  
Long Term Outcome ◽  
Long Term Prognosis ◽  
Prospective Longitudinal

ObjectiveChildhood craniopharyngiomas (CP) are often diagnosed after a long duration of history (DOH). Tumor size, hypothalamic involvement (HI), and obesity are associated with reduced overall survival (OS) and functional capacity (FC). The effect of DOH and specific symptoms in history on presentation at initial diagnosis and long-term prognosis are unknown.DesignRetrospective analysis of patients' records and prospective longitudinal follow-up.MethodsHistories of 411 CP patients recruited in HIT Endo, KRANIOPHARYNGEOM 2000 were retrospectively evaluated for DOH, symptoms, and characteristics. The effect of specific manifestations and DOH on clinical presentation and tumor characteristics at time of initial CP diagnosis and long-term outcome were analyzed. Main outcome measures were 10-year OS and progression-free survival (PFS), FC, and BMI during longitudinal follow-up.ResultsMedian DOH was 6 months (range: 0.1–108 months) and correlated with age at diagnosis. Tumor size, HI, degree of resection, and BMI at diagnosis were not related to DOH. In multivariate analysis adjusted for age at diagnosis, only hydrocephalus was found to have a relevant influence on DOH. Visual and neurological deficits were associated with larger initial tumor size and impaired 10-year OS. Weight gain and growth failure were observed with longest DOH. PFS and FC were not related to any specific symptom. Endocrine deficits at diagnosis were associated with long DOH.ConclusionsCP is frequently diagnosed after long DOH, especially in older children. However, DOH was not associated with tumor size, HI, survival, or FC. Visual and neurological deficits necessitate rapid diagnostic workup.

Long-term outcome of lumbar disc surgery: an experience from Pakistan

2010 ◽  
Vol 12 (6) ◽  
pp. 666-670 ◽  
Author(s):  
Ahmed Bakhsh
Keyword(s):  
Pain Relief ◽  
Lumbar Disc ◽  
Foot Drop ◽  
Neurological Deficits ◽  
Leg Pain ◽  
Lumbar Disc Surgery ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Disc Surgery

Object The author conducted a study to determine the long-term outcome of lumbar disc surgery on relief of sciatic leg pain. Methods This was a retrospective observational study conducted at Fauji Foundation Hospital, Rawalpindi, Pakistan. The author reviewed medical records of 68 patients who underwent lumbar disc surgery for sciatic pain during the period 1995–2004. All patients were physically examined and interviewed. Results Lumbar disc surgery yielded complete pain relief in 79.41% of the cases. In 14.7% of the cases surgery failed to give any pain relief, and in 5.88% it yielded partial pain relief. At up to 10 years postoperatively, 27.77% of patients remained absolutely pain free. Pain recurred in 12.82% of cases after 1 year, in 35.89% during the first 5 years, and in 51.28% after 10 years. Pain recurred in the same leg in 63.88%, in the contralateral leg in 19.44%, and in both legs in 16.66%. Neurological deficits did not improve in any case except in 1 case of foot drop. New neurological deficits developed postoperatively in 8.82% of cases in the form of foot drop and calf muscle weakness. Conclusions Surgery provided immediate pain relief in 79.41% of cases, but the long-term outcome of lumbar disc surgery was not satisfactory.

scholarly journals THE EFFECT OF THE PRESENCE OF EPILEPTIC ATTACKS ON THE CLINICAL DURATION OF SUPRATENTORIAL BRAIN MENINGIOMAS

2020 ◽  
Vol 73 (3) ◽  
pp. 541-545
Author(s):  
Taras О. Studeniak ◽  
Volodymyr І. Smolanka ◽  
Olesya I. Borovik
Keyword(s):  
Postoperative Period ◽  
Epileptic Seizures ◽  
Neurological Deficits ◽  
General Group ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Complications And Mortality ◽  
The Brain ◽  
Late Postoperative Period

The aim: To study the effect of epileptic seizures in patients with supratentorial brain meningiomas on the clinical course of meningiomas in the early and late postoperative period. Materials and methods: A retrospective analysis of the course of the disease was performed in 242 patients with total removed supratentorial meningioma of the brain (general group). Long-term outcome of the disease was estimated in 176 people (a catamnesis group). Results: The occurrence of a new neurological deficit was observed in 18 (18.0±3.8 %) patients out of 100 among patients with epileptic seizures before surgery and in 19 (13.4±2.9 %) out of 142 among those who had no seizures. The mortality rate was 1 (1.0±1.0 %) in the group of patients with seizures and 3 (2.8±1.4 %) in the group of patients without seizures before surgery. The prevalence of new neurological deficits in the catamnesis group is 14 (19.2±4.6 %) of 73 patients with epileptic seizures before surgery and 17 (16.5±3.7 %) of 103 patients without seizures. Mortality was 3 cases (4.1±2.3 %) in patients with seizures and 9 cases (8.7±2.8 %) among patients without seizures. Conclusions: No data have been obtained that the presence of epileptic seizures affects the incidence of new neurological deficits, complications and mortality after surgical treatment of meningiomas in the early and late postoperative period.

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