End-tidal carbon dioxide levels in patients with post-concussion syndrome during neurocognitive and physical tasks compared to a normative control group

Brain Injury ◽  
2018 ◽  
Vol 32 (13-14) ◽  
pp. 1824-1833 ◽  
Author(s):  
Patrick Siedlecki ◽  
Paolo Sanzo ◽  
Carlos Zerpa ◽  
Ian Newhouse
Keyword(s):  
Carbon Dioxide ◽  
Control Group ◽  
Post Concussion Syndrome ◽  
End Tidal Carbon Dioxide ◽  
Carbon Dioxide Levels ◽  
End Tidal

Abstract 320: End-Tidal Carbon Dioxide Can Guide Fluid Resuscitation in a Cecal Ligation and Puncture Induced Rat Model of Sepsis

Circulation ◽  
2018 ◽  
Vol 138 (Suppl_2) ◽  
Author(s):  
Jing Xu ◽  
Guanghui Zheng ◽  
Liangliang Wu ◽  
Xiangshao Fang ◽  
Yue Wang ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Survival Time ◽  
Fluid Resuscitation ◽  
Rat Model ◽  
Cecal Ligation ◽  
Control Group ◽  
Cecal Ligation And Puncture ◽  
End Tidal Carbon Dioxide ◽  
Lactate Levels ◽  
End Tidal

Introduction: Abnormal levels of end-tidal carbon dioxide (ETCO 2 ) may reflect a derangement in perfusion, metabolism, or gas exchange. It is unclear if ETCO 2 can be used for fluid resuscitation (FR) compared with traditional mean arterial pressure (MAP) as an outcome predictor in sepsis. Hypothesis: Use of ETCO2 is better than MAP in guiding fluid resuscitation to improve lactate levels and microcirculatory blood flow in sepsis. Methods: Thirty-five male Sprague-Dawley rats weighing 350-400g were randomized to: 1) SHAM, n=5; 2) cecal ligation and puncture (CLP) Control group (with CLP, without FR, n=10); 3) ETCO 2 group (with CLP, FR began when ETCO 2 ≤25 mmHg, n=10) and 4) MAP group (with CLP, FR began when MAP≤100 mmHg, n=10). Lactate level, cardiac output (CO), perfused small vessel density (PSVD) and sublingual microvascular flow index (MFI) was assessed at baseline, 2 h, 4 h, 8 h, 10 h and 12 h post-CLP. Survival duration was recorded. Results: After FR,CO in the ETCO 2 group increased compared with the MAP group 12h after CLP while lactate levels decreased compared with the Control and MAP groups (p<0.05) (Figure-1). Both sublingual PSVD and MFI decreased after CLP in the control group and MAP group but significantly improved in the ETCO 2 group 8h post-CLP. The average survival time in the ETCO 2 group was significantly greater than MAP group (Figure-2). Conclusions: ETCO 2 guided FR was associated with improved CO, lactate, microcirculatory flow, and survival time compared to MAP guided FR in a CLP-induced rat model of sepsis.

scholarly journals The Influence of CO2 Production and Physiological Deadspace on End-Tidal CO2 During Controlled Ventilation: A Study Using a Mechanical Model

1989 ◽  
Vol 17 (4) ◽  
pp. 482-486 ◽  
Author(s):  
M. A. Stockwell ◽  
W. Bruce ◽  
N. Soni
Keyword(s):  
Carbon Dioxide ◽  
Mechanical Model ◽  
Carbon Dioxide Production ◽  
Lung Model ◽  
Co2 Production ◽  
Controlled Ventilation ◽  
End Tidal Carbon Dioxide ◽  
Carbon Dioxide Levels ◽  
End Tidal ◽  
End Tidal Co2

A mechanical lung model was used to investigate the effect of varying carbon dioxide production and deadspace on the end-tidal carbon dioxide levels achieved during mechanical ventilation when using the Bain, Humphrey ADE, and circle systems. Both factors had significant influence on end-tidal cardon dioxide concentration and could result in values in excess of those considered acceptable in clinical practice. The implications of the results are discussed.

Intraabdominal Carbon Dioxide Insufflation in the Pregnant Ewe

1996 ◽  
Vol 85 (6) ◽  
pp. 1395-1402. ◽  
Author(s):  
Antonio M. Cruz ◽  
Lucy C. Southerland ◽  
Tanya Duke ◽  
Hugh G. G. Townsend ◽  
James G. Ferguson ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Blood Flow ◽  
Intraabdominal Pressure ◽  
Control Group ◽  
Uterine Blood Flow ◽  
Carbon Dioxide Insufflation ◽  
Carbon Dioxide Pneumoperitoneum ◽  
Arterial Blood ◽  
End Tidal Carbon Dioxide ◽  
End Tidal

Background Laparoscopic surgical procedures are being performed in pregnant women with increasing frequency. Maternal-fetal physiologic changes occurring during intraabdominal carbon dioxide insufflation are poorly understood, and maternal-fetal safety is of concern during carbon dioxide pneumoperitoneum. A previous pilot study using end-tidal carbon dioxide-guided ventilation resulted in maternal and fetal acidosis and tachycardia during carbon dioxide pneumoperitoneum. Using serial arterial PCO2 to guide ventilation, this study was designed to evaluate maternal-fetal cardiopulmonary status, uterine blood flow, and the intraamniotic pressure effects of intraabdominal carbon dioxide insufflation in singleton pregnant ewes between 120 and 135 days of gestation. Methods In a prospective randomized cross-over study, nine ewes were to receive either abdominal insufflation with carbon dioxide to an intraabdominal pressure of 15 mmHg (n = 9; insufflation group) or receive no insufflation (n = 9; control group). Anesthesia was induced with thiopental and maintained with end-tidal halothane (1 to 1.5 minimum alveolar concentration/100% oxygen). Mechanical ventilation was guided by serial maternal arterial blood gas analysis to maintain PaCO2 between 35 and 40 mmHg. Data from insufflated animals were collected during insufflation (60 min) and after desufflation (30 min). Control group data were collected and matched to similar time intervals for 90 min. Ewes were allowed to recover, and after a rest period (48 h) they were entered in the cross-over study. Results During insufflation there was a significant increase (P &lt; 0.05) in maternal PaCO2 to end-tidal carbon dioxide gradient and minute ventilation, with concomitant decreases in maternal end-tidal carbon dioxide and PaO2. Intraamniotic pressure increased significantly during insufflation. No significant changes were observed in maternal hemodynamic variables, fetal variables, or in uterine blood flow during the study. There were no fetal deaths or preterm labor in any of the animals during the experiment. Conclusions During the 1-h insufflation, a marked increase in PaCO2-to-end-tidal carbon dioxide gradient was observed, suggesting that capnography may be an inadequate guide to ventilation during carbon dioxide pneumoperitoneum in the pregnant patient. No other significant circulatory changes were observed.

End tidal carbon dioxide levels during the resuscitation of prematurely born infants

2012 ◽  
Vol 88 (10) ◽  
pp. 783-787 ◽  
Author(s):  
Vadivelam Murthy ◽  
Anthony O'Rourke-Potocki ◽  
Nikesh Dattani ◽  
Grenville F. Fox ◽  
Morag E. Campbell ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
End Tidal Carbon Dioxide ◽  
Carbon Dioxide Levels ◽  
End Tidal ◽  
Prematurely Born Infants

Intraoperative End-Tidal Carbon Dioxide Levels and Derived Calculations Correlated with Outcome in Trauma Patients

1996 ◽  
Vol 41 (4) ◽  
pp. 606-611 ◽  
Author(s):  
Robert F. Wilson ◽  
James G. Tyburski ◽  
Susan M. Kubinec ◽  
Karyn M. Warsow ◽  
Howard C. Larky ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Trauma Patients ◽  
End Tidal Carbon Dioxide ◽  
Carbon Dioxide Levels ◽  
End Tidal

End-Tidal Carbon Dioxide Levels in the Early Detection of Air Embolism

1975 ◽  
Vol 3 (1) ◽  
pp. 58-59 ◽  
Author(s):  
W. J. Pattison
Keyword(s):  
Carbon Dioxide ◽  
Early Detection ◽  
Air Embolism ◽  
Sitting Position ◽  
End Tidal Carbon Dioxide ◽  
Carbon Dioxide Levels ◽  
End Tidal

Two cases of air embolism in patients anaesthetized in the sitting position are described. The emboli, though producing no signs and therefore probably small, were readily detected by the fall in the end tidal CO2 fraction. Techniques for the detection of air emboli are briefly reviewed.

scholarly journals Cardiorespiratory variables, bispectral index and recovery of anesthesia in dogs anesthetized with isoflurane, treated or not with tramadol

2008 ◽  
Vol 60 (3) ◽  
pp. 613-619 ◽  
Author(s):  
P.A. Borges ◽  
N. Nunes ◽  
V.F. Barbosa ◽  
E.D.V. Conceição ◽  
C.T.D. Nishimori ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Heart Rate ◽  
Bispectral Index ◽  
Recovery Time ◽  
Saline Solution ◽  
Control Group ◽  
End Tidal Carbon Dioxide ◽  
Index Changes ◽  
End Tidal

It was studied fortuitous cardiorespiratory and bispectral index changes in dogs anesthetized with isoflurane associated or not to tramadol. Sixteen dogswere distributed in two groups named CG (control group) and TG (tramadol group). General anesthesia was induced in all animals with isoflurane via mask. After 10 minutes, the animals of CG received 0.05ml/kg of saline solution at 0.9%, and TG received 2mg/kg of tramadol, both via intramuscular. It was evaluated heart rate, systolic, diastolic and mean arterial pressures; electrocardiography; respiratory rate; oxihemoglobin saturation; end tidal carbon dioxide; bispectral index and recovery of anesthesia. The administration of tramadol in dogs anesthetized with isoflurane did not produce changes in cardiorespiratory variables, bispectral index and anesthetic recovery time. In addition, this association promoted good quality of anesthetic recovery.

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