Effect of ECG-gating retinal photographs on retinal vessel caliber measurements in subjects with and without type 2 diabetes

2021 ◽  
Author(s):  
Anchal Lal ◽  
Neha Dave ◽  
Oliver J. Gibbs ◽  
Michael Anthony (Tony) Barry ◽  
Annika Sood ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Retinal Vessel ◽  
Ecg Gating ◽  
Retinal Vessel Caliber ◽  
Retinal Photographs

The Relationship of Retinal Vessel Caliber With Erectile Dysfunction in Patients With Type 2 Diabetes

2013 ◽  
Vol 54 (12) ◽  
pp. 7234 ◽  
Author(s):  
Sky K. H. Chew ◽  
Yamna Taouk ◽  
Jing Xie ◽  
Theona E. Nicolaou ◽  
Jie J. Wang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Erectile Dysfunction ◽  
Retinal Vessel ◽  
Retinal Vessel Caliber ◽  
Relationship Of ◽  
The Relationship

Retinal Vessel Caliber and Microvascular and Macrovascular Disease in Type 2 Diabetes

Ophthalmology ◽  
2007 ◽  
Vol 114 (10) ◽  
pp. 1884-1892 ◽  
Author(s):  
Ronald Klein ◽  
Barbara E.K. Klein ◽  
Scot E. Moss ◽  
Tien Y. Wong
Keyword(s):  
Type 2 Diabetes ◽  
Macrovascular Disease ◽  
Retinal Vessel ◽  
Retinal Vessel Caliber

Retinal vessel reactivity is not attenuated in patients with type 2 diabetes compared with matched controls and is associated with peripheral endothelial function in controls

2019 ◽  
Vol 33 (9) ◽  
pp. 641-647 ◽  
Author(s):  
Jonathan Mathias Baier ◽  
Kristian Løkke Funck ◽  
Line Petersen ◽  
Liv Vernstrøm ◽  
Søren T. Knudsen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Endothelial Function ◽  
Retinal Vessel

scholarly journals Retinal venular tortuosity and fractal dimension predict incident retinopathy in adults with type 2 diabetes: the Edinburgh Type 2 Diabetes Study

Diabetologia ◽  
2021 ◽  
Author(s):  
Rachel B. Forster ◽  
◽  
Emmanuel Sandoval Garcia ◽  
Anniek J. Sluiman ◽  
Sheila M. Grecian ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Diabetic Retinopathy ◽  
Fractal Dimension ◽  
Statistical Significance ◽  
Fractal Dimensions ◽  
Retinal Vessel ◽  
Related Factors ◽  
Discriminative Ability

Abstract Aims/hypothesis Our aim was to determine whether a range of prespecified retinal vessel traits were associated with incident diabetic retinopathy in adults with type 2 diabetes. Methods In the prospective observational cohort Edinburgh Type 2 Diabetes Study of 1066 adults with type 2 diabetes, aged 60–75 years at recruitment, 718 were free from diabetic retinopathy at baseline. Baseline retinal traits including vessel widths, tortuosity (curvature) and fractal dimensions (network complexity), were quantified using fundus camera images and semiautomated software, and analysed using logistic regression for their association with incident diabetic retinopathy over 10 years. Results The incidence of diabetic retinopathy was 11.4% (n = 82) over 10 years. After adjustment for a range of vascular and diabetes-related risk factors, both increased venular tortuosity (OR 1.51; 95% CI 1.15, 1.98; p = 0.003) and decreased fractal dimension (OR 0.75; 95% CI 0.58, 0.96; p = 0.025) were associated with incident retinopathy. There was no evidence of an association with arterial tortuosity, and associations between measurements of vessel widths and retinopathy lost statistical significance after adjustment for diabetes-related factors and vascular disease. Adding venular tortuosity to a model including established risk factors for diabetic retinopathy (HbA1c, BP and kidney function) improved the discriminative ability (C statistic increased from 0.624 to 0.640, p = 0.013), but no such benefit was found with fractal dimension. Conclusions/interpretation Increased retinal venular tortuosity and decreased fractal dimension are associated with incident diabetic retinopathy, independent of classical risk factors. There is some evidence that venular tortuosity may be a useful biomarker to improve the predictive ability of models based on established retinopathy risk factors, and its inclusion in further risk prediction modelling is warranted. Graphical abstract

scholarly journals Retinal Vessel Diameter Changes in Relation to Dark Adaptation and Acute Hyperglycemia

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Per Kappelgaard ◽  
Stig K. Holfort ◽  
Oliver N. Klefter ◽  
Michael Larsen
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Retinopathy ◽  
Dark Adaptation ◽  
Retinal Vessel ◽  
Vessel Diameter ◽  
Postprandial Hyperglycemia ◽  
Oral Glucose ◽  
Retinal Artery ◽  
Retinal Vessel Diameters

The purpose of this experimental clinical study was to assess the effects of dark adaptation and acute changes in glycemia on retinal vessel diameters in men. The study included 14 patients (mean age 63 years, range 48–74 years) with type 2 diabetes mellitus and minimal or no diabetic retinopathy. Retinal vessel diameters were assessed using infrared photography before and after dark adaptation, first while fasting and then at peak hyperglycemia during an oral glucose tolerance test (OGTT). Dark adaptation was accompanied by retinal vasodilatation, both during fasting (mean glycemia 7.6 ± 1.7 mM) and postprandial hyperglycemia (15.7 ± 4.2 mM). When fasting, the increase in vein diameter during dark adaptation was 2.0% after 20 min (P=0.018) and 2.9% after 40 min (P=0.010). When subjects were hyperglycemic, the increase during dark adaptation was 2.8% for retinal vein diameters (P=0.027) and 2.0% for retinal artery diameters after 20 min (P=0.002) and 1.7% for retinal artery diameters after 40 min (P=0.022). For identical conditions of light/dark adaptation, retinal vessels were dilated when subjects were fasting compared to postprandial hyperglycemia. Thus, darkness and fasting were both associated with retinal vasodilation in this short-term experiment in patients with type 2 diabetes. Future studies should determine whether both the stimuli of vasodilation lead to retinal hyperperfusion, which would support that they may be involved in the aggravation of diabetic retinopathy.

scholarly journals A Deep Learning Model for Screening Type 2 Diabetes from Retinal Photographs

2022 ◽  
Author(s):  
Jae-Seung Yun ◽  
Jaesik Kim ◽  
Sang-Hyuk Jung ◽  
Seon-Ah Cha ◽  
Seung-Hyun Ko ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Deep Learning ◽  
Learning Model ◽  
Retinal Photographs ◽  
Deep Learning Model

scholarly journals Prevalence of diabetic retinopathy in individuals with type 2 diabetes who had recorded diabetic retinopathy from retinal photographs in Catalonia (Spain)

2015 ◽  
Vol 99 (12) ◽  
pp. 1628-1633 ◽  
Author(s):  
Antonio Rodriguez-Poncelas ◽  
Sònia Miravet-Jiménez ◽  
Aina Casellas ◽  
Joan Francesc Barrot-De La Puente ◽  
Josep Franch-Nadal ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Retinopathy ◽  
Retinal Photographs
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