scholarly journals Tumour control probability after Ruthenium-106 brachytherapy for choroidal melanomas

2020 ◽  
Vol 59 (8) ◽  
pp. 918-925 ◽  
Author(s):  
Charlotte A. Espensen ◽  
Ane L. Appelt ◽  
Lotte S. Fog ◽  
Juliette Thariat ◽  
Anita B. Gothelf ◽  
...  
Author(s):  
J. E. Marsden

Abstract Aims: The aim of this work is to report on the tumour control probability (TCP) of a UK cohort of lung stereotactic ablative radiotherapy patients (n = 198) for a range of dose and fractionations common in the UK. Materials and methods: TCP values for 3 (54 Gy), 5 (55 and 60 Gy) and 8 (50 Gy) fraction (#) schemes were calculated with the linear-quadratic Marsden TCP model using the Biosuite software. Results: TCP values of 100% were computed for the 3 # and for 5 # (α/β = 10 Gy) cohorts; reduced to 99% (range 97–100) for the 5 # cohort only when an α/β of 20 Gy was used. The average TCP value for the 50 Gy in 8 # regime was 97% (range 92–99, α/β = 10 Gy) and 64% (range 48–79, α/β = 20 Gy). Statistical significant differences were observed between the α/β of 10 Gy versus 20 Gy groups and between all data grouped by fraction. Conclusion: TCPs achievable with current planning techniques in the UK have been presented. The ultra-conservative 50 Gy in 8 # scheme returns a significantly lower TCP than the other regimes.


2020 ◽  
Vol Volume 14 ◽  
pp. 339-346 ◽  
Author(s):  
Fariba Ghassemi ◽  
Shahab Sheibani ◽  
Mojtaba Arjmand ◽  
Hosein Poorbaygi ◽  
Emad Kouhestani ◽  
...  

2011 ◽  
Vol 30 (1) ◽  
pp. 1-19 ◽  
Author(s):  
J. Gong ◽  
M. M. Dos Santos ◽  
C. Finlay ◽  
T. Hillen

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