Calcified cartilage differs in patients with end-stage primary osteoarthritis and secondary osteoarthritis due to rheumatoid arthritis of the hip joint

Purpose. To assess the vascularity of the femoral head and determine how it is related to the destruction of the arthritic hip joint. The process of destructive arthropathy in arthritic hip joints is variable. Some patients with osteoarthritis of the hip have rapidly progressive destructive changes resulting in the disappearance of the femoral head. Method. Six femoral heads from patients diagnosed with rapidly destructive arthropathy and 6 femoral heads from patients with secondary osteoarthritis caused by acetabular dysplasia were analysed to reveal the association between blood capillaries and osteoclasts. The von Willebrand Factor immunostaining and counterstaining with Mayer's haematoxylin were used to label the microvessels and osteoclasts in formalin-fixed, paraffin-embedded specimens of femoral heads. The numbers of immunostained microvessels and osteoclasts in selected regions were counted. Result. The microvascular density of the bone surfaces of rapidly progressive arthritic hips was hypervascular. Osteoclasts were also found in increased numbers on the bone surfaces of rapidly progressive arthritic hips. The higher microvascular density coincided with extensive bone destruction and with the increased osteoclast count. Conclusion. These findings suggested that hypervascularity of the granulation in the femoral head may be associated with bone and joint destruction.

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THU0715 Estimation of the effect of foot orthotics on hip joint loading for rheumatoid arthritis patients using mri-based musculoskeletal models: a pilot study

10.1136/annrheumdis-2017-eular.2169 ◽

2017 ◽

Author(s):

MB Simonsen ◽

K Næsborg-Andersen ◽

MR Kowalski ◽

K Hørslev-Petersen ◽

MS Andersen

Keyword(s):

Rheumatoid Arthritis ◽

Pilot Study ◽

Hip Joint ◽

Joint Loading ◽

Musculoskeletal Models

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Secondary Osteoarthritis in Patients With Rheumatoid Arthritis Appears as Severe as Inflammation According to Physician Visual Analog Scales, Regardless of Disease Severity

Osteoarthritis and Cartilage ◽

10.1016/j.joca.2017.02.382 ◽

2017 ◽

Vol 25 ◽

pp. S220-S221

Author(s):

J.R. Chua ◽

T. Pincus ◽

I. Castrejon ◽

K. Gibson ◽

J.A. Block

Keyword(s):

Rheumatoid Arthritis ◽

Disease Severity ◽

Secondary Osteoarthritis ◽

Visual Analog Scales

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Axillary Peripheral Nerve Stimulation for Painful End‐Stage Primary Osteoarthritis of the Shoulder: A Case Report

Neuromodulation Technology at the Neural Interface ◽

10.1111/ner.13089 ◽

2019 ◽

Vol 23 (6) ◽

pp. 878-880

Author(s):

John Taylor Mansfield ◽

Mehul J. Desai

Keyword(s):

Case Report ◽

Peripheral Nerve ◽

Nerve Stimulation ◽

Peripheral Nerve Stimulation ◽

Primary Osteoarthritis ◽

End Stage

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Comparison of Intermediate-term Outcomes of Total Ankle Arthroplasty in Primary and Ligamentous Post-traumatic Osteoarthritis

Foot & Ankle International ◽

10.1177/1071100719866472 ◽

2019 ◽

Vol 40 (11) ◽

pp. 1273-1281 ◽

Cited By ~ 2

Author(s):

Gun-Woo Lee ◽

Asep Santoso ◽

Keun-Bae Lee

Keyword(s):

Short Form ◽

Total Ankle Arthroplasty ◽

Level Of Evidence ◽

Ankle Arthroplasty ◽

Radiographic Outcomes ◽

Primary Osteoarthritis ◽

Post Traumatic ◽

American Orthopaedic ◽

End Stage

Background: Ankle ligamentous injuries without fracture can result in end-stage ligamentous post-traumatic osteoarthritis, which may cause ligamentous imbalance after total ankle arthroplasty (TAA). However, outcomes of TAA in these patients are not well known. The purpose of this study was to evaluate intermediate-term clinical and radiographic outcomes of TAA in patients with ligamentous post-traumatic osteoarthritis and compare them with results of TAA for patients with primary osteoarthritis. Methods: We enrolled 114 patients (119 ankles) with consecutive primary TAA using HINTEGRA prosthesis at a mean follow-up duration of 6.0 years (range, 3-13). We divided all patients into 2 groups according to the etiology of osteoarthritis: (1) primary osteoarthritis group (69 ankles) and (2) ligamentous post-traumatic osteoarthritis group (50 ankles). Results: There was no significant intergroup difference in mean Ankle Osteoarthritis Scale (AOS), American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hindfoot score, Short Form-36 Physical Component Summary, visual analog scale pain score, ankle range of motion, or complications at the final follow-up. However, the final tibiotalar angle was less corrected to 4.2 degrees in the ligamentous post-traumatic osteoarthritis group compared to 2.7 degrees in the primary osteoarthritis group ( P = .001). More concomitant procedures were required at the index surgery for the ligamentous post-traumatic osteoarthritis group ( P = .001). The estimated 5-year survivorship was 93.4% (primary osteoarthritis group: 91.3%; ligamentous post-traumatic osteoarthritis group: 95.8%). Conclusions: Clinical outcomes, complication rate, and 5-year survivorship of TAA in ankles with primary and ligamentous post-traumatic osteoarthritis were comparable with intermediate-term follow-up. Our results suggest that TAA would be a reliable treatment in ankles with ligamentous post-traumatic osteoarthritis when neutrally aligned stable ankles are achieved postoperatively. Level of Evidence: Level III, retrospective cohort study.

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