Evaluation of spin in the abstracts of systematic reviews and meta-analyses of studies on opioid use disorder

2021 ◽  
pp. 1-9
Author(s):  
Greg Balcerak ◽  
Samuel Shepard ◽  
Ryan Ottwell ◽  
Wade Arthur ◽  
Micah Hartwell ◽  
...  
Keyword(s):  
Systematic Reviews ◽  
Opioid Use Disorder ◽  
Opioid Use ◽  
Meta Analyses

scholarly journals Methodological quality of systematic reviews referenced in clinical practice guidelines for the treatment of opioid use disorder

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0181927 ◽  
Author(s):  
Andrew Ross ◽  
Justin Rankin ◽  
Jason Beaman ◽  
Kelly Murray ◽  
Philip Sinnett ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Systematic Reviews ◽  
Clinical Practice Guidelines ◽  
Practice Guidelines ◽  
Methodological Quality ◽  
Opioid Use Disorder ◽  
Opioid Use

scholarly journals Pain and Opioid Use: Evidence for Integrating Acupuncture Into Treatment Planning

2021 ◽  
Vol 10 ◽  
pp. 216495612110425
Author(s):  
Elizabeth Sommers ◽  
Sivarama Prasad Vinjamury ◽  
Jennifer Noborikawa
Keyword(s):  
Pain Management ◽  
Large Scale ◽  
Opioid Use Disorder ◽  
Veterans Health ◽  
Health Administration ◽  
Opioid Use ◽  
Related Factors ◽  
Treatment Protocols ◽  
Meta Analyses

The epidemics of pain and opioid use pose unique challenges. Comprehensive approaches are required to address minds, bodies and spirits of individuals who live with pain and/or opioid use. The lack of an effective “quick fix” for either condition necessitates developing effective, innovative and multi-disciplinary avenues for treatment. This analytic article reviews epidemiological and demographic factors associated with pain and with opioid use and additional challenges posed by the Covid-19 epidemic. Several large-scale studies and meta-analyses have examined the role of acupuncture as a nonpharmacological approach to pain management as well as a component of comprehensive strategies to address opioid use disorder. We review and describe these in the context of safety, effectiveness, access and cost-related factors. With one in four U.S. hospitals as well as 88% of Veterans Health Administration facilities incorporating acupuncture, the feasibility of mobilizing and scaling up these treatment resources is being developed and demonstrated. We also identify potential facilitators and barriers to implementing acupuncture treatment. As part of a multi-disciplinary approach to pain management and/or opioid use disorder, we suggest that integrating acupuncture into treatment protocols may represent a viable strategy that is based on and consistent with public health principles.

scholarly journals Facilitators of and barriers to buprenorphine initiation for people with opioid use disorder in the emergency department: protocol for a scoping review

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e053207
Author(s):  
Nikki Bozinoff ◽  
Charlene Soobiah ◽  
Terri Rodak ◽  
Christine Bucago ◽  
Katie Kingston ◽  
...  
Keyword(s):  
Emergency Department ◽  
Lived Experience ◽  
Scoping Review ◽  
Opioid Use Disorder ◽  
French Language ◽  
Future Research ◽  
Opioid Use ◽  
Scoping Reviews ◽  
Barriers To Implementation ◽  
Meta Analyses

IntroductionBuprenorphine–naloxone is recommended as a first-line agent for the treatment of opioid use disorder. Although initiation of buprenorphine in the emergency department (ED) is evidence based, barriers to implementation persist. A comprehensive review and critical analysis of both facilitators of and barriers to buprenorphine initiation in ED has yet to be published. Our objectives are (1) to map the implementation of buprenorphine induction pathway literature and synthesise what we know about buprenorphine pathways in EDs and (2) to identify gaps in this literature with respect to barriers and facilitators of implementation.Methods and analysisWe will conduct a scoping review to comprehensively search the literature, map the evidence and identify gaps in knowledge. The review will adhere to the Preferred Reporting Items for Systematic Reviews and Meta-analyses Protocols Extension for Scoping Reviews and guidance from the Joanna Briggs Institution for conduct of scoping reviews. We will search Medline, APA, PsycINFO, CINAHL, Embase and IBSS from 1995 to present and the search will be restricted to English and French language publications. Citations will be screened in Covidence by two trained reviewers. Discrepancies will be mediated by consensus. Data will be synthesised using a hybrid, inductive–deductive approach, informed by the Consolidated Framework for Implementation Research as well as critical theory to guide further interpretation.Ethics and disseminationThis review does not require ethics approval. A group of primary knowledge users, including clinicians and people with lived experience, will be involved in the dissemination of findings including publication in peer-reviewed journals. Results will inform future research, current quality improvement efforts in affiliated hospitals, and aide the creation of a more robust ED response to the escalating overdose crisis.

scholarly journals The role of social network support on treatment outcomes for medication for opioid use disorder: a systematic review protocol

2020 ◽  
Author(s):  
Navin Kumar ◽  
Benjamin A. Howell ◽  
Marcus Alexander ◽  
Patrick G. O'Connor
Keyword(s):  
Systematic Review ◽  
Social Network ◽  
Treatment Outcomes ◽  
Systematic Reviews ◽  
Opioid Use Disorder ◽  
Opioid Use ◽  
Support Functions ◽  
Network Support ◽  
Social Network Support

Abstract Background Although medications for opioid use disorder (MOUD) models are the most efficacious evidence-based treatment for opioid use disorder, there remains a high percentage of patients experiencing unfavorable treatment outcomes. Greater understanding of how social network support functions with respect to MOUD treatment outcomes may possibly increase treatment outcomes. Social network support are the kinds of support, such as assistance or help, that people receive from friends, family, peers and neighbors, paid or unpaid, in their social network. We aim to provide quality evidence to understand the role of social network support on MOUD treatment outcomes. Methods A systematic review of experimental and observational studies will be conducted. PubMed, MEDLINE, Embase, PsycINFO and Sociological Abstracts will be searched, updated to capture current literature. Primary outcomes will include adherence to MOUD, defined as continuation in or completion of an MOUD program; and opioid use, defined as the percentage of urine samples negative for opioids and/or self-reported drug use. The systematic review will be conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Quality assessments will be conducted using criteria from the Cochrane Handbook. A narrative synthesis will be conducted for all included studies. Discussion This systematic review seeks to provide policymakers, administrators, practitioners and researchers with a systematic and reproducible strategy to query the literature around the role of social network support on MOUD treatment outcomes. Systematic review registration International Prospective Register for Systematic Reviews (PROSPERO), CRD42018095645.

scholarly journals Evaluating comparative effectiveness of psychosocial interventions adjunctive to opioid agonist therapy for opioid use disorder: A systematic review with network meta-analyses

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0244401
Author(s):  
Danielle Rice ◽  
Kimberly Corace ◽  
Dianna Wolfe ◽  
Leila Esmaeilisaraji ◽  
Alan Michaud ◽  
...  
Keyword(s):  
Contingency Management ◽  
Psychosocial Interventions ◽  
Opioid Use Disorder ◽  
Treatment Retention ◽  
Controlled Trials ◽  
Opioid Use ◽  
Agonist Therapy ◽  
Opioid Agonist ◽  
Opioid Agonist Therapy ◽  
Meta Analyses

Background Guidelines recommend that individuals with opioid use disorder (OUD) receive pharmacological and psychosocial interventions; however, the most appropriate psychosocial intervention is not known. In collaboration with people with lived experience, clinicians, and policy makers, we sought to assess the relative benefits of psychosocial interventions as an adjunct to opioid agonist therapy (OAT) among persons with OUD. Methods A review protocol was registered a priori (CRD42018090761), and a comprehensive search for randomized controlled trials (RCT) was conducted from database inception to June 2020 in MEDLINE, Embase, PsycINFO and the Cochrane Central Register of Controlled Trials. Established methods for study selection and data extraction were used. Primary outcomes were treatment retention and opioid use (measured by urinalysis for opioid use and opioid abstinence outcomes). Odds ratios were estimated using network meta-analyses (NMA) as appropriate based on available evidence, and in remaining cases alternative approaches to synthesis were used. Results Seventy-two RCTs met the inclusion criteria. Risk of bias evaluations commonly identified study limitations and poor reporting with regard to methods used for allocation concealment and selective outcome reporting. Due to inconsistency in reporting of outcome measures, only 48 RCTs (20 unique interventions, 5,404 participants) were included for NMA of treatment retention, where statistically significant differences were found when psychosocial interventions were used as an adjunct to OAT as compared to OAT-only. The addition of rewards-based interventions such as contingency management (alone or with community reinforcement approach) to OAT was superior to OAT-only. Few statistically significant differences between psychosocial interventions were identified among any other pairwise comparisons. Heterogeneity in reporting formats precluded an NMA for opioid use. A structured synthesis was undertaken for the remaining outcomes which included opioid use (n = 18 studies) and opioid abstinence (n = 35 studies), where the majority of studies found no significant difference between OAT plus psychosocial interventions as compared to OAT-only. Conclusions This systematic review offers a comprehensive synthesis of the available evidence and the limitations of current trials of psychosocial interventions applied as an adjunct to OAT for OUD. Clinicians and health services may wish to consider integrating contingency management in addition to OAT for OUD in their settings to improve treatment retention. Aside from treatment retention, few differences were consistently found between psychosocial interventions adjunctive to OAT and OAT-only. There is a need for high-quality RCTs to establish more definitive conclusions. Trial registration PROSPERO registration CRD42018090761.

scholarly journals The role of social network support on treatment outcomes for medication for opioid use disorder: a systematic review protocol

2020 ◽  
Author(s):  
Navin Kumar ◽  
Benjamin A. Howell ◽  
Marcus Alexander ◽  
Patrick G. O'Connor
Keyword(s):  
Systematic Review ◽  
Social Network ◽  
Treatment Outcomes ◽  
Systematic Reviews ◽  
Opioid Use Disorder ◽  
Opioid Use ◽  
Support Functions ◽  
Network Support ◽  
Social Network Support

Abstract Background Although medications for opioid use disorder (MOUD) models are the most efficacious evidence-based treatment for opioid use disorder, there remains a high percentage of patients experiencing unfavorable treatment outcomes. Greater understanding of how social network support functions with respect to MOUD treatment outcomes may possibly improve treatment outcomes. Social network support are the kinds of support, such as assistance or help, that people receive from friends, family, peers and neighbors, paid or unpaid, in their social network. We aim to provide quality evidence to understand the role of social network support on MOUD treatment outcomes. Methods A systematic review of experimental and observational studies will be conducted. PubMed, MEDLINE, Embase, PsycINFO and Sociological Abstracts will be searched. Primary outcomes will include adherence to MOUD, defined as continuation in or completion of an MOUD program; and opioid use, defined as the percentage of urine samples negative for opioids and/or self-reported drug use. The systematic review will be conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Quality assessments will be conducted using criteria from the Cochrane Handbook. A narrative synthesis will be conducted for all included studies. Discussion This systematic review seeks to provide policymakers, administrators, practitioners and researchers with a systematic and reproducible strategy to query the literature around the role of social network support on MOUD treatment outcomes. Systematic review registration International Prospective Register for Systematic Reviews (PROSPERO), CRD42018095645.

Hotspots in Psychology – 2020 Edition

2020 ◽  
Vol 228 (1) ◽  
pp. 1-2
Author(s):  
Michael Bošnjak ◽  
Nadine Wedderhoff
Keyword(s):  
Systematic Reviews ◽  
Research Synthesis ◽  
Synthesis Methods ◽  
Common Denominator ◽  
The Common ◽  
Meta Analyses

Abstract. This editorial gives a brief introduction to the six articles included in the fourth “Hotspots in Psychology” of the Zeitschrift für Psychologie. The format is devoted to systematic reviews and meta-analyses in research-active fields that have generated a considerable number of primary studies. The common denominator is the research synthesis nature of the included articles, and not a specific psychological topic or theme that all articles have to address. Moreover, methodological advances in research synthesis methods relevant for any subfield of psychology are being addressed. Comprehensive supplemental material to the articles can be found in PsychArchives ( https://www.psycharchives.org ).

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