Early Detection of Risk of Onset for Dementia of the Alzheimer Type and Subtle Executive Dysfunction after TBI Using the Test of Verbal Conceptualization and Fluency During Clinical Neuropsychological Assessment: Two Case Studies

2007 ◽  
Vol 14 (3) ◽  
pp. 224-229 ◽  
Author(s):  
Arthur MacNeill Horton ◽  
Cecil R. Reynolds
2019 ◽  
Vol 64 (2) ◽  
pp. S50
Author(s):  
Jocelyn Lebow ◽  
Angela Mattke ◽  
Janna Gewirtz O'Brien ◽  
Cassandra Narr ◽  
Marcie Billings ◽  
...  

2019 ◽  
Vol 11 (1) ◽  
pp. 80-86
Author(s):  
Ezgi Bakırcıoğlu-Duman ◽  
Zeynep Acar ◽  
Gülçin Benbir ◽  
Hande Yüceer ◽  
Hürtan Acar ◽  
...  

Morvan syndrome (MoS) is typically characterized by neuromyotonia, sleep dysfunction, dysautonomia, and cognitive dysfunction. However, MoS patients with mild peripheral nerve hyperexcitability (PNH) or encephalopathy features have been described. A 46-year-old woman presented with a 2-month history of constipation, hyperhidrosis, and insomnia. Neurologic examination revealed muscle twitching and needle electromyography showed myokymic discharges in all limbs. No clinical or electrophysiological features of neuromyotonia were present. Although the patient denied any cognitive symptoms, neuropsychological assessment revealed executive dysfunction, while other cognitive domains were preserved. Cranial and spinal MRIs were unrevealing and tumor investigation proved negative. Polysomnography examination revealed total insomnia, which was partially reversed upon immune-modulatory therapy. Investigation of a broad panel of antibodies revealed serum leucine-rich glioma inactivated protein 1 and contactin-associated protein 2 antibodies. The features of this case indicate that the presentation of PNH syndromes may show significant variability and that MoS patients may not necessarily exhibit full-scale PNH and encephalopathy symptoms.


2021 ◽  
Author(s):  
Konstantinos Priftis ◽  
Massimo Prior ◽  
Leonardo Meneghetti ◽  
Teresa Mercogliano ◽  
Matteo Bendini

SARS-CoV-2 resulting in COVID-19 can affect the brain and cause neuropsychological disorders (e.g., executive dysfunction and memory difficulties). Recently the presence of more focal and isolated neuropsychological signs has been also reported, in the domain of language disorders (e.g., alexia without agraphia, conduction aphasia). We reported on patient LM affected by a left occipito-temporal ischemic stroke after SARS-CoV-2. LM had a largely preserved overall cognitive profile, but he presented with severe alexia without agraphia. We suggest that focal and isolated neuropsychological dysfunction can be observed in patients with stroke after SARS-CoV-2. Neuropsychological assessment and rehabilitation should be promptly provided to these patients.


2015 ◽  
Vol 19 (4) ◽  
pp. 179-184 ◽  
Author(s):  
Jan Filipczyk ◽  
Zbigniew Stanik
Keyword(s):  

1989 ◽  
Vol 23 (2) ◽  
pp. 148-156 ◽  
Author(s):  
Kenichiro Okadome ◽  
Hiroshi Eguchi ◽  
Takashi Yukizane ◽  
Shinsuke Mii ◽  
Yoichi Muto ◽  
...  

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 50s-50s
Author(s):  
I. Fadhil ◽  
M. Alkuwari ◽  
F. Al Tahan ◽  
K. Alsaleh ◽  
D. Alsaadoon

Background: Breast cancer is the most frequently diagnosed cancer among women in Gulf countries. Although breast cancer incidence rates in the Gulf are substantially lower than rates in developed countries, yet an increasing trend is evident. Most breast cancers are diagnosed at an advanced stage, only 23.3% of patients presented with localized tumors and less than 2% with in situ, making improvements to early detection of breast cancer a priority. There has been good progress and investment in early detection of breast cancer program in Gulf countries based on augmenting breast cancer awareness through public education, investing in mammographic based screening and improving infrastructure. Nevertheless, development of breast cancer early detection programs in most of the Gulf countries has been based on sporadic investments and actions rather than on a planned, approved and resource-linked national control plan. In many instances the scientific evidence-base for such investments has not been obtained and the evaluation of implemented programs is lacking. Aim: To review breast cancer screening, early detection practices in Gulf region, outlines enablers and identifies priorities for scaling up early detection programs in Gulf countries. Methods: The study relies heavily on review of published literature and data gathered through interview and discussion with key informants from government and nongovernment institutions at the studied countries. Results: Four case studies will be discussed from Bahrain, UAE, Kuwait and Saudi Arabia. Conclusion: Breast cancer is a major and increasing problem in Gulf countries, but it is still largely diagnosed at an advanced stage. While mammography based screening programs have been initiated in Gulf countries, however they generally have limited uptake, with very little evidence to support their effectiveness, largely because their attempts at education on the curability of breast cancer, and their endeavors to dispel the prevalent myths on breast cancer, have not been sufficiently successful. Thus, it is essential that the highest priority in each country should be improving awareness, early diagnosis of breast cancer, by public and professional education. This will require considerable investment in training primary care professionals, organizing referral mechanisms and setting up multidisciplinary breast cancer diagnosis and treatment facilities across the countries. While population-level screening for breast cancer is feasible in Gulf countries, yet careful consideration for available resources is critical for success. Moreover, it is important to pilot any screening programs prior to national roll-out.


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