Management and outcomes of sinus histiocytosis with massive lymphadenopathy (Rosai Dorfman Disease)

2019 ◽  
Vol 61 (4) ◽  
pp. 905-911
Author(s):  
Esin C. Namoglu ◽  
Mitchell E. Hughes ◽  
John P. Plastaras ◽  
Daniel J. Landsburg ◽  
Amit Maity ◽  
...  
Keyword(s):  
Sinus Histiocytosis ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

Primary Pancreatic Sinus Histiocytosis With Massive Lymphadenopathy (Rosai-Dorfman Disease): An Unusual Extranodal Manifestation Clinically Simulating Malignancy

2010 ◽  
Vol 134 (2) ◽  
pp. 276-278 ◽  
Author(s):  
Mark Podberezin ◽  
Ronald Angeles ◽  
Grace Guzman ◽  
David Peace ◽  
Sujata Gaitonde
Keyword(s):  
Adipose Tissue ◽  
Lymph Node ◽  
Unusual Case ◽  
Sinus Histiocytosis ◽  
Gastrointestinal System ◽  
Rare Entity ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

Abstract Sinus histiocytosis with massive lymphadenopathy (SHML), also called Rosai-Dorfman disease, is a rare entity. Its etiology and pathogenesis are still essentially unclear. The histologic hallmark of this disease is proliferation of distinctive histiocytes within lymph node sinuses and in extranodal sites. Approximately 23% of patients with SHML, documented in the SHML Registry, presented with disease primarily in extranodal sites, and very few cases of SHML (<1%) involving the gastrointestinal system have been described in the literature. We report an unusual case of primary pancreatic SHML with infiltration of the process into peripancreatic, perinephric, and perisplenic adipose tissue, simulating malignancy.

scholarly journals Rosai–Dorfman Disease (Sinus Histiocytosis with Massive Lymphadenopathy) of the Pancreas: Third Reported Occurrence

2012 ◽  
Vol 43 (4) ◽  
pp. 626-629 ◽  
Author(s):  
Minerva A. Romero Arenas ◽  
Aatur D. Singhi ◽  
Ralph H. Hruban ◽  
Andrew M. Cameron
Keyword(s):  
Sinus Histiocytosis ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

scholarly journals Treatment of sinus histiocytosis with massive lymphadenopathy (rosai-dorfman disease): Report of a case and literature review

2001 ◽  
Vol 69 (1) ◽  
pp. 67-71 ◽  
Author(s):  
Alessandro Pulsoni ◽  
Gabriel Anghel ◽  
Paolo Falcucci ◽  
Roberta Matera ◽  
Edoardo Pescarmona ◽  
...  
Keyword(s):  
Literature Review ◽  
Sinus Histiocytosis ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

scholarly journals Rosai-Dorfman disease of the colon presented as small solitary polypoid lesion

Rare Tumors ◽  
2010 ◽  
Vol 2 (1) ◽  
pp. 5-7 ◽  
Author(s):  
Munenori Ide ◽  
Takayuki Asao ◽  
Takatomo Yoshida ◽  
Junko Hirato ◽  
Tatsuo Shimura ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Gastrointestinal Tract ◽  
Microscopic Study ◽  
Polypoid Lesion ◽  
Sinus Histiocytosis ◽  
Whole Body ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
History Of ◽  
Submucosal Mass

Rosai-Dorfman disease (RDD) was formerly known as “sinus histiocytosis with massive lymphadenopathy”, and cases involving the gastrointestinal tract are rare. We present a case of pure extranodal RDD, resected as a polypoid lesion in colonoscopic study. The patient was a 62-year old woman with a history of sigmoidectomy for unexplained peritonitis. Microscopic study of the polypoid lesion showed the submucosal mass with histological and immunological features of RDD. The whole body computed tomography revealed neither lymphadenopathy nor tumor-like mass.

scholarly journals Rosai-Dorfman Disease: Rare Pulmonary Involvement Mimicking Pulmonary Langerhans Cell Histiocytosis and Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Rashid AL Umairi ◽  
Danielle Blunt ◽  
Wedad Hana ◽  
Matthew Cheung ◽  
Anastasia Oikonomou
Keyword(s):  
Langerhans Cell Histiocytosis ◽  
Corticosteroid Treatment ◽  
Pulmonary Involvement ◽  
Skin Lesions ◽  
Langerhans Cell ◽  
Sinus Histiocytosis ◽  
Review Of The Literature ◽  
Massive Lymphadenopathy ◽  
Pulmonary Langerhans Cell Histiocytosis ◽  
Rosai Dorfman Disease

Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare nonmalignant lymphohistiocytic proliferative disorder. We report a patient with RDD who presented with multiple skin lesions, pulmonary involvement, and CT manifestations mimicking Langerhans cell histiocytosis, which improved after initiation of corticosteroid treatment.

scholarly journals Primary Rosai-Dorfman Disease of Bone: A Report of Two Cases

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Andrew B. Ross ◽  
Kirkland W. Davis ◽  
Darya Buehler ◽  
Brian Y. Chan
Keyword(s):  
Young Adults ◽  
Cervical Lymphadenopathy ◽  
Sinus Histiocytosis ◽  
Osseous Lesion ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
Extranodal Disease

Rosai-Dorfman disease (RDD), sometimes known as sinus histiocytosis with massive lymphadenopathy, is a rare histiocytic disorder that most commonly presents as painless, massive cervical lymphadenopathy in young adults. Extranodal disease can occur in up to 40% of patients but primary involvement of bone is rare. We present two cases of primary RDD of bone: one case of multifocal osseous RDD presenting as a painful lesion in the elbow, and one case of a solitary osseous lesion presenting as a painful lesion in the wrist.

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