A low-cost geometry calibration procedure for a modular cone-beam X-ray CT system

2020 ◽  
Vol 35 (3) ◽  
pp. 252-265 ◽  
Author(s):  
V. Nguyen ◽  
J. De Beenhouwer ◽  
J. G. Sanctorum ◽  
S. Van Wassenbergh ◽  
S. Bazrafkan ◽  
...  
2021 ◽  
Vol 7 (3) ◽  
pp. 54
Author(s):  
Van Nguyen ◽  
Joaquim G. Sanctorum ◽  
Sam Van Van Wassenbergh ◽  
Joris J. J. Dirckx ◽  
Jan Sijbers ◽  
...  

Compared to single source systems, stereo X-ray CT systems allow acquiring projection data within a reduced amount of time, for an extended field-of-view, or for dual X-ray energies. To exploit the benefit of a dual X-ray system, its acquisition geometry needs to be calibrated. Unfortunately, in modular stereo X-ray CT setups , geometry misalignment occurs each time the setup is changed, which calls for an efficient calibration procedure. Although many studies have been dealing with geometry calibration of an X-ray CT system, little research targets the calibration of a dual cone-beam X-ray CT system. In this work, we present a phantom-based calibration procedure to accurately estimate the geometry of a stereo cone-beam X-ray CT system. With simulated as well as real experiments, it is shown that the calibration procedure can be used to accurately estimate the geometry of a modular stereo X-ray CT system thereby reducing the misalignment artifacts in the reconstruction volumes.


2017 ◽  
Vol 44 (5) ◽  
pp. 1692-1706 ◽  
Author(s):  
Hongkai Yang ◽  
Kejun Kang ◽  
Yuxiang Xing

2009 ◽  
Vol 2009 ◽  
pp. 1-9 ◽  
Author(s):  
Shouping Zhu ◽  
Jie Tian ◽  
Guorui Yan ◽  
Chenghu Qin ◽  
Jinchao Feng

A prototype cone-beam micro-CT system for small animal imaging has been developed by our group recently, which consists of a microfocus X-ray source, a three-dimensional programmable stage with object holder, and a flat-panel X-ray detector. It has a large field of view (FOV), which can acquire the whole body imaging of a normal-size mouse in a single scan which usually takes about several minutes or tens of minutes. FDK method is adopted for 3D reconstruction with Graphics Processing Unit (GPU) acceleration. In order to reconstruct images with high spatial resolution and low artifacts, raw data preprocessing and geometry calibration are implemented before reconstruction. A method which utilizes a wire phantom to estimate the residual horizontal offset of the detector is proposed, and 1D point spread function is used to assess the performance of geometric calibration quantitatively. System spatial resolution, image uniformity and noise, and low contrast resolution have been studied. Mouse images with and without contrast agent are illuminated in this paper. Experimental results show that the system is suitable for small animal imaging and is adequate to provide high-resolution anatomic information for bioluminescence tomography to build a dual modality system.


Author(s):  
Roger H. Johnson ◽  
Alan C. Nelson ◽  
David H. Burns

X-ray microscopy has received considerable attention over the years, since it has the potential of producing high-resolution images of thick specimens in air. We are developing an x-ray microtomograph for three-dimensional imaging of small biological specimens. The instrument, shown in Figure 1, has much in common with projection x-ray microscopes of decades past, but incorporates several technological advances of recent years to partially overcome the limitations of the older instruments. The most important of these are the use of a planar solid-state detector and the provision for volume reconstruction. We describe the design for a relatively low-cost instrument intended for 3-D imaging of biological specimens up to ten cubic millimeters in size.The x-ray source for the microtomograph consists of a modified SEM. The electron beam, in spot mode and focused to about ten nanometers, impinges on a thin foil target to produce an emergent, low-intensity cone beam of characteristic and Bremsstrahlung x-rays. The foil resides in close proximity to an optional aluminum filter and a thin beryllium window which terminates the evacuated electron column. The specimen is mounted on a precision rotating shaft within two millimeters of the target foil. A two-dimensional detector is placed ten to forty centimeters from the sample, providing direct projection magnifications of up to 200 times. Two-dimensional projection views are collected at each of many angular orientations as the sample is rotated through 360 degrees. Cone beam backprojection algorithms are then applied to reconstruct a threedimensional data set.


2007 ◽  
Vol 80 (954) ◽  
pp. 476-482 ◽  
Author(s):  
A Amer ◽  
T Marchant ◽  
J Sykes ◽  
J Czajka ◽  
C Moore
Keyword(s):  
X Ray ◽  

1993 ◽  
Author(s):  
Pascal Sire ◽  
Philippe Rizo ◽  
M. Martin

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