scholarly journals Hyaluronic acid modified MPEG-b-PAE block copolymer aqueous micelles for efficient ophthalmic drug delivery of hydrophobic genistein

Drug Delivery ◽  
2018 ◽  
Vol 25 (1) ◽  
pp. 1258-1265 ◽  
Author(s):  
Cong Li ◽  
Rui Chen ◽  
Mengzhen Xu ◽  
Jiyan Qiao ◽  
Liang Yan ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hyaluronic Acid ◽  
Block Copolymer ◽  
Ophthalmic Drug Delivery ◽  
Ophthalmic Drug ◽  
Aqueous Micelles

Methylprednisolone esters of hyaluronic acid in ophthalmic drug delivery: in vitro and in vivo release studies

1992 ◽  
Vol 80 (1-3) ◽  
pp. 161-169 ◽  
Author(s):  
Kristiina Kyyrönen ◽  
Lisbeth Hume ◽  
Luca Benedetti ◽  
Arto Urtti ◽  
Elizabeth Topp ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hyaluronic Acid ◽  
Ophthalmic Drug Delivery ◽  
In Vivo Release ◽  
Release Studies ◽  
Ophthalmic Drug

scholarly journals Flexible Polymeric Nanosized Micelle for Ophthalmic Drug Delivery: Research Progress in Recent Three Years

2021 ◽  
Author(s):  
Zhiguo Li ◽  
Mingting Liu ◽  
Lingjie Ke ◽  
Li-Juan Wang ◽  
Caisheng Wu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Complex Structure ◽  
Research Progress ◽  
Ophthalmic Drug Delivery ◽  
Ophthalmic Drug ◽  
Delivery Technology

The eye is a complex structure with a variety of anatomical barriers and clearance mechanisms, so the provision of safe and effective ophthalmic drug delivery technology is a major challenge....

scholarly journals Ophthalmic Drug Delivery Systems for the Treatment of Retinal Diseases: Basic Research to Clinical Applications

2010 ◽  
Vol 51 (11) ◽  
pp. 5403 ◽  
Author(s):  
Henry F. Edelhauser ◽  
Cheryl L. Rowe-Rendleman ◽  
Michael R. Robinson ◽  
Daniel G. Dawson ◽  
Gerald J. Chader ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Basic Research ◽  
Delivery Systems ◽  
Clinical Applications ◽  
Retinal Diseases ◽  
Ophthalmic Drug Delivery ◽  
Ophthalmic Drug

Nanocarriers for treatment of ocular neovascularization in the back of the eye: new vehicles for ophthalmic drug delivery

Nanomedicine ◽  
2015 ◽  
Vol 10 (13) ◽  
pp. 2093-2107 ◽  
Author(s):  
Hsin-Hui Shen ◽  
Elsa C Chan ◽  
Jia Hui Lee ◽  
Youn-Shen Bee ◽  
Tsung-Wu Lin ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ocular Neovascularization ◽  
Ophthalmic Drug Delivery ◽  
Ophthalmic Drug

Polycarboxylic acid nanoparticles for ophthalmic drug delivery: anex vivoevaluation with human cornea

2004 ◽  
Vol 21 (8) ◽  
pp. 841-855 ◽  
Author(s):  
T. K. De ◽  
E. J. Bergey ◽  
S. J. Chung ◽  
D. J. Rodman ◽  
D. J. Bharali ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Human Cornea ◽  
Polycarboxylic Acid ◽  
Ophthalmic Drug Delivery ◽  
Ophthalmic Drug

scholarly journals Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Xiaohong Hu ◽  
Lingyun Hao ◽  
Huaiqing Wang ◽  
Xiaoli Yang ◽  
Guojun Zhang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Contact Lens ◽  
Contact Lenses ◽  
Drug Carriers ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Advantages And Disadvantages ◽  
Ophthalmic Drug Delivery ◽  
Ophthalmic Drug ◽  
Polymeric Hydrogels

Soft contact lenses can improve the bioavailability and prolong the residence time of drugs and, therefore, are ideal drug carriers for ophthalmic drug delivery. Hydrogels are the leading materials of soft contact lenses because of their biocompatibility and transparent characteristic. In order to increase the amount of load drug and to control their release at the expected intervals, many strategies are developed to modify the conventional contact lens as well as the novel hydrogel contact lenses that include (i) polymeric hydrogels with controlled hydrophilic/hydrophobic copolymer ratio; (ii) hydrogels for inclusion of drugs in a colloidal structure dispersed in the contact lenses; (iii) ligand-containing hydrogels; (iv) molecularly imprinted polymeric hydrogels; (v) hydrogel with the surface containing multilayer structure for drugs loading and releasing. The advantages and disadvantages of these strategies in modifying or designing hydrogel contact lenses for extended ophthalmic drug delivery are analyzed in this paper.

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