Fast Determination of Haloperidol in Pharmaceutical Preparations Using HPLC with a Monolithic Silica Column

2005 ◽  
Vol 28 (20) ◽  
pp. 3169-3179 ◽  
Author(s):  
Imran Ali ◽  
Hassan Y. Aboul‐Enein
Keyword(s):  
Pharmaceutical Preparations ◽  
Monolithic Silica ◽  
Fast Determination ◽  
Silica Column ◽  
Monolithic Silica Column

scholarly journals Chiral Monolithic Silica-Based HPLC Columns for Enantiomeric Separation and Determination: Functionalization of Chiral Selector and Recognition of Selector-Selectand Interaction

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5241
Author(s):  
Mufarreh Asmari ◽  
Xiaoyu Wang ◽  
Natalia Casado ◽  
Marjan Piponski ◽  
Sergiy Kovalenko ◽  
...  
Keyword(s):  
Enantiomeric Separation ◽  
Chiral Selector ◽  
Covalent Functionalization ◽  
Monolithic Silica ◽  
Silica Column ◽  
Chiral Compounds ◽  
Mobile Phase Additive ◽  
Monolithic Silica Column ◽  
Impurity Determination

This review draws attention to the use of chiral monolithic silica HPLC columns for the enantiomeric separation and determination of chiral compounds. Properties and advantages of monolithic silica HPLC columns are also highlighted in comparison to conventional particle-packed, fused-core, and sub-2-µm HPLC columns. Nano-LC capillary monolithic silica columns as well as polymeric-based and hybrid-based monolithic columns are also demonstrated to show good enantioresolution abilities. Methods for introducing the chiral selector into the monolithic silica column in the form of mobile phase additive, by encapsulation and surface coating, or by covalent functionalization are described. The application of molecular modeling methods to elucidate the selector–selectand interaction is discussed. An application for enantiomeric impurity determination is also considered.

Efficient application of monolithic silica column to determination of illicit heroin street sample by HPLC

Il Farmaco ◽  
2004 ◽  
Vol 59 (3) ◽  
pp. 237-239 ◽  
Author(s):  
Marco Macchia ◽  
Simone Bertini ◽  
Claudio Mori ◽  
Caterina Orlando ◽  
Chiara Papi ◽  
...  
Keyword(s):  
Monolithic Silica ◽  
Silica Column ◽  
Monolithic Silica Column
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