Preparation, characterization, and evaluation of amino acid modified magnetic nanoparticles: drug delivery and MRI contrast agent applications

2018 ◽  
Vol 23 (10) ◽  
pp. 1156-1167 ◽  
Author(s):  
Hamed Nosrati ◽  
Marziyeh Salehiabar ◽  
Zahra Bagheri ◽  
Hamid Rashidzadeh ◽  
Soodabeh Davaran ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Amino Acid ◽  
Magnetic Nanoparticles ◽  
Contrast Agent ◽  
Mri Contrast Agent ◽  
Mri Contrast ◽  
Modified Magnetic Nanoparticles

Controlling the thickness of polymeric shell on magnetic nanoparticles loaded with doxorubicin for targeted delivery and MRI contrast agent

2012 ◽  
Vol 87 (4) ◽  
pp. 2593-2604 ◽  
Author(s):  
Sumanta Kumar Sahu ◽  
Swatilekha Maiti ◽  
Arindam Pramanik ◽  
Sudip Kumar Ghosh ◽  
Panchanan Pramanik
Keyword(s):  
Magnetic Nanoparticles ◽  
Contrast Agent ◽  
Targeted Delivery ◽  
Mri Contrast Agent ◽  
Mri Contrast

Porous Fe3O4-SiO2 core-shell nanorods as high-performance MRI contrast agent and drug delivery vehicle

2017 ◽  
Vol 428 ◽  
pp. 340-347 ◽  
Author(s):  
Muhammad Shahbaz Beg ◽  
Jeotikanta Mohapatra ◽  
Lina Pradhan ◽  
D. Patkar ◽  
D. Bahadur
Keyword(s):  
Drug Delivery ◽  
Contrast Agent ◽  
High Performance ◽  
Mri Contrast Agent ◽  
Core Shell ◽  
Delivery Vehicle ◽  
Mri Contrast ◽  
Drug Delivery Vehicle

scholarly journals Theragnostic Magnetic Core-Shell Nanoparticle as Versatile Nanoplatform for Magnetic Resonance Imaging and Drug Delivery

2021 ◽  
Vol 11 (5) ◽  
pp. 13276-13289
Keyword(s):  
Electron Microscopy ◽  
Drug Delivery ◽  
Scanning Electron Microscopy ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Magnetic Core ◽  
Mri Contrast Agent ◽  
Core Shell ◽  
Mri Contrast ◽  
Scanning Electron

In this study, magnetic core-shell (MCS) nanoparticles were prepared as theragnostic potential nanoplatforms for simultaneously targeted drug delivery systems for tamoxifen and diagnosis. MCS nanoparticles were prepared in a well-shaped spherical form by the o/w emulsion method and characterized by means of dynamic light scattering (DLS), Scanning electron microscopy (SEM), Nuclear magnetic resonance (NMR), transform infrared (FT-IR) spectroscopy, and vibrating sample magnetometer (VSM). Scanning electron microscopy (SEM) indicated spherical nanostructures' formation with the final average particle size of around 80 nm. The findings proved the superparamagnetic properties of the MCS nanoparticles with relatively high-magnetization values (11.69 emu/g), which indicate that they were sensitive enough to external magnetic fields as a magnetic drug carrier. The nanoparticles showed 8.14% and 52.19% drug loading and encapsulation efficiency, respectively. MCS nanoparticles showed sustained release behavior for 120 h in the phosphate-buffered saline (PBS, pH= 7.4, 5.4) at 37 °C. The ratio between transverse and longitudinal relaxivity (r2/r1) value of the MCS nanoparticles was around 20, indicating their potential as a T2 MRI contrast agent. It can be concluded that the prepared MCS nanoparticles may serve as a promising carrier as an MRI contrast agent and targeted controlled anticancer drug delivery.

MRI contrast agent for molecular imaging of the HER2/neu receptor using targeted magnetic nanoparticles

2010 ◽  
Vol 13 (6) ◽  
pp. 2285-2293 ◽  
Author(s):  
Samira Rasaneh ◽  
Hossein Rajabi ◽  
Mohammad Hossein Babaei ◽  
Shahram Akhlaghpoor
Keyword(s):  
Magnetic Nanoparticles ◽  
Molecular Imaging ◽  
Contrast Agent ◽  
Mri Contrast Agent ◽  
Mri Contrast
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